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Jay Hinton

@jayhinton.bsky.social

Salmonella admirer & Prof of Microbiology - Working on Salmonella bloodstream infections (iNTS) in sub- Saharan Africa context. Functional genomics. T1D.

2,192 Followers  |  1,289 Following  |  1,288 Posts  |  Joined: 15.10.2023
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Posts by Jay Hinton (@jayhinton.bsky.social)

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Dozens of researchers will move to France from US following high-profile bid to lure talent Large proportion worked at Columbia University, which had its grants cut and frozen by the administration of US President Donald Trump.

Almost all of the scientists were previously at US institutions

go.nature.com/4qMlrUR

10.02.2026 15:43 β€” πŸ‘ 328    πŸ” 123    πŸ’¬ 13    πŸ“Œ 27
Poster for the 2nd Aerosols and Microbiology conference, June 9-11, 2026, at Leeds Marriott Hotel, UK, with microscopic aerosol imagery.

Poster for the 2nd Aerosols and Microbiology conference, June 9-11, 2026, at Leeds Marriott Hotel, UK, with microscopic aerosol imagery.

Join us for our 2nd Aerosols and Microbiology: Bridging disciplines to advance health & environmental sustainability meeting.

πŸ“…Date: 9–11 June 2026
πŸ“ Location: Leeds Marriott Hotel, UK

Register your place: https://microb.io/Aerosols2026

#Microbiology #Conference #Health #Research

27.02.2026 15:01 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Don’t deprioritize curiosity-driven research Around the world, governments are demanding that research funding follow broader political priorities. They should be careful what they wish for.

Don’t deprioritize curiosity-driven research www.nature.com/articles/d41...

27.02.2026 15:41 β€” πŸ‘ 14    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

By my count, this is the third CDC outbreak notice in the past three months involving Moringa leaf and various Salmonella strains. What's with that?

13.02.2026 22:09 β€” πŸ‘ 4    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
25.02.2026 17:23 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Technical Programme Manager | Liverpool School of Tropical Medicine Technical Project ManagerLocation: LiverpoolContract: Fixed-term contract until March 2028Salary: Β£47,389 - Β£59,967The Parish Lab at the Liverpool School of Tropical Medicine focuses on antimicrobial ...

Are you interested in being the first biologist in our new team? Come join our small but growing group. Deadline for applications is 3rd March. #Tuberculosis πŸ§ͺ🦠 #TBDrugDiscovery

19.02.2026 05:00 β€” πŸ‘ 12    πŸ” 9    πŸ’¬ 0    πŸ“Œ 1
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Congratulations to Mariana Byndloss @maribyndloss.bsky.social for her promotion to Associate Professor with tenure at Vanderbilt University @vanderbilt.edu

Photo credit: BΓ€umler lab archives

20.02.2026 03:45 β€” πŸ‘ 49    πŸ” 4    πŸ’¬ 3    πŸ“Œ 0

So happy to see this story out! Incredible work on systematically standardizing a good cellular model for iNTS-macrophage interactions, which clearly shows how different Salmonella pathovariants are in terms of intracellular behaviour!
@jayhinton.bsky.social

30.01.2026 13:11 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Bloodstream-associated Salmonella Typhimurium and Enteritidis iNTS pathovariants hyper-replicate in human macrophages https://www.biorxiv.org/content/10.64898/2026.01.28.702237v1

29.01.2026 03:17 β€” πŸ‘ 9    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1
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National Lab of the Rockies, formerly NREL, lays off more than 130 employees The cuts impacted staffers engaged in both research and operations at the lab.

😒 this is seriously unfortunate. Many places, same story.

www.cpr.org/2026/02/09/n...

11.02.2026 03:57 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
63 Fellows Elected to the American Academy of Microbiology The American Academy of Microbiology elected 63 new fellows to the Class of 2026.

Congratulations to Γ‡agla TΓΌkel @caglatukel.bsky.social for her election to fellowship in the American Academy of Microbiology! asm.social/2OC

13.02.2026 18:54 β€” πŸ‘ 26    πŸ” 8    πŸ’¬ 3    πŸ“Œ 0
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CHECK IT OUT πŸ¦ πŸ‘€

Very cool article by science journalist Carrie Arnold reviewing recent research from leading laboratories on how the unique shape of a microbial #biofilm emerges from interactions of its component microbes with each other and their environment

www.quantamagazine.org/how-a-biofil...

21.04.2025 18:30 β€” πŸ‘ 82    πŸ” 20    πŸ’¬ 5    πŸ“Œ 0
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Large-scale analysis of bacterial genomes reveals thousands of lytic phages - Nature Microbiology Diverse genomes of lytic phages are found in bacterial assemblies, challenging assumptions about the nature of the lytic lifestyle.

#NewResearch

Diverse genomes of lytic phages are found in bacterial assemblies, challenging assumptions about the nature of the lytic lifestyle.

#MicroSky 🦠

www.nature.com/articles/s41...

02.01.2026 14:06 β€” πŸ‘ 16    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Persistent virulent phages exist across bacterial isolates - Nature Microbiology The long-term existence of diverse virulent phages within cultures of Escherichia coli and others challenges the virulent–temperate dichotomy and points to non-canonical phage lifestyles.

#NewResearch

The long-term existence of diverse virulent phages within cultures of Escherichia coli and others challenges the virulent–temperate dichotomy and points to non-canonical phage lifestyles.

#MicroSky 🦠 @peterdoug.bsky.social @emggroupucph.bsky.social

www.nature.com/articles/s41...

02.01.2026 14:05 β€” πŸ‘ 15    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0

Tragic news -Helene’s death is an immense loss for the Salmonella research community. We’re grateful for her ground-breaking discoveries about Salmonella virulence

We will miss her great insights & kindness. Helene faced her cancer diagnosis with impressive courage & openness. An example to us all.

24.12.2025 09:33 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Friday we lost a brilliant mind, colleague, and friend to her battle with pancreatic cancer. Those who knew her will remember Helene Andrews-Polymenis for her warmth, generosity and leadership. She will be missed by many. RIP

23.12.2025 08:36 β€” πŸ‘ 72    πŸ” 17    πŸ’¬ 8    πŸ“Œ 1
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Predicting drug inactivation by changes in bacterial growth dynamics - npj Antimicrobials and Resistance npj Antimicrobials and Resistance - Predicting drug inactivation by changes in bacterial growth dynamics

Our recent paper in npj Antimicrobials and Resistance is a great example of scientific serendipity: after staring at thousands of bacterial growth curves over many studies, we started wondering whether the curve shapes themselves carry mechanistic information 1/9 🦠πŸ§ͺ
www.nature.com/articles/s44...

22.12.2025 15:25 β€” πŸ‘ 45    πŸ” 25    πŸ’¬ 2    πŸ“Œ 2
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High-throughput transposon mutagenesis defines the essential genome of diverse phages Phages are important drivers of bacterial evolution with therapeutic potential as antimicrobials. However, gaps in our understanding of phages and our inability to rapidly engineer them with new genet...

#microsky #phagesky

The 3rd (? Lost track!) manuscript on a CRISPR/anti-CRISPR -based transposon tool to study gene essentiality in #phages

www.biorxiv.org/content/10.6...

21.12.2025 05:01 β€” πŸ‘ 28    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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A family of linear plasmid phages that detect a quorum-sensing autoinducer exists in multiple bacterial species | mBio The discovery of quorum-sensing responsive linear plasmid phages has transformed understanding of phage-bacterial interactions by demonstrating inter-domain chemical communication. To date, however, e...

The final form of my 2nd postdoc paper with the Bassler Lab! Turns out our favorite quorum-sensing phage isn’t a one-off, but rather a member of a globally dispersed family of phages that sense a universal autoinducer.

#phagesky #microsky

journals.asm.org/doi/10.1128/...

21.12.2025 16:19 β€” πŸ‘ 77    πŸ” 28    πŸ’¬ 0    πŸ“Œ 1
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Embracing the unknown: Proteomic insights into the human microbiome Protein-level investigations into the human microbiome provide insights into active microbial functions. Recently, ValdΓ©s-Mas etΒ al. introduced a metagenome-informed metaproteomics approach to functio...

Thank you Shaopu_Wang and colleagues for highlighting our latest work in a nice N&V

www.cell.com/cell-metabol...

www.cell.com/cell/abstrac...

07.04.2025 16:45 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Bacterial population structure and clade-specific sampling affect machine learning predictions of antimicrobial resistance (AMR). Top: An illustration of defining clades for genomes in one species. R: resistant (triangles), S: susceptible (circles). Bottom left: An example of training scenarios for scheme B based on the clade splitting in shown above. Models were trained on all samples except for resistant or susceptible samples from one clade. The held-out genomes from the same clade were used as the test sets. Bottom right: The precision and recall scores for scheme B; a-random and b-random indicate testing on random train-test splits of the pathological unbalanced data.

Bacterial population structure and clade-specific sampling affect machine learning predictions of antimicrobial resistance (AMR). Top: An illustration of defining clades for genomes in one species. R: resistant (triangles), S: susceptible (circles). Bottom left: An example of training scenarios for scheme B based on the clade splitting in shown above. Models were trained on all samples except for resistant or susceptible samples from one clade. The held-out genomes from the same clade were used as the test sets. Bottom right: The precision and recall scores for scheme B; a-random and b-random indicate testing on random train-test splits of the pathological unbalanced data.

#MachineLearning methods are used to predict #AntimicrobialResistance #AMR from genomic data. @lbarquist.bsky.social &co show that sampling biases driven by population structure severely undermine the accuracy of AMR prediction models even with large datasets @plosbiology.org πŸ§ͺ plos.io/4iZ0zXQ

17.12.2025 17:35 β€” πŸ‘ 30    πŸ” 12    πŸ’¬ 1    πŸ“Œ 1
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European Academy of Microbiology Announces Professor CecΓ­lia M. Arraiano as New President - FEMS The European Academy of Microbiology (EAM) is proud to announce the appointment of Professor CecΓ­lia Maria Arraiano as its new President, effective 1 January 2026. Prof. Arraiano brings a distinguishe...

Very good news ‼️

fems-microbiology.org/european-aca...

@femsmicro.org

15.12.2025 11:23 β€” πŸ‘ 9    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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An iterative fractionation approach to identify antimicrobial proteins in snake venom Antimicrobial resistance (AMR) increasingly poses a significant global health challenge. New antimicrobials are desperately needed, driving the need to explore novel sources of natural products. Snake...

πŸ””New PreprintπŸ””

Just posted on Access Microbiology (first time using this platform, seems great!) our work on looking for antimicrobial proteins in snake venom. This is work from the first bit of funding I received and the project (1/3)

www.microbiologyresearch.org/content/jour...

#MicroSky

10.12.2025 15:19 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

New paper from the lab!
Led by Patrick MΓΌller: we show that non-antibiotic compounds β€” but not macrolide antibiotics β€” can induce an efflux pump that protects Bacteroidaceae from macrolides.
A neat twist on drug–microbe interactions... www.tandfonline.com/doi/full/10....

09.12.2025 10:33 β€” πŸ‘ 19    πŸ” 11    πŸ’¬ 0    πŸ“Œ 1

Very interesting new protective response in live (!) neutrophils against bacterial infection:

27.11.2025 22:03 β€” πŸ‘ 1    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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STREAMS guidelines: standards for technical reporting in environmental and host-associated microbiome studies - Nature Microbiology This Consensus Statement presents the standards for technical reporting in environmental and host-associated microbiome studies (STREAMS) guidelines.

#ConsensusStatement

A new Consensus Statement presents the standards for technical reporting in environmental and host-associated microbiome studies (STREAMS) guidelines.

#MicroSky #MicrobiomeSky 🦠

www.nature.com/articles/s41...

03.12.2025 17:09 β€” πŸ‘ 10    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
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Systematic discovery of TIR-based immune signaling systems in bacteria Toll/interleukin-1 receptor (TIR) domains are important for immune signaling across humans, plants and bacteria. These domains were recently found to produce immune signaling molecules in plant immuni...

#microsky #phagesky #phge defence

Preprint from the @soreklab.bsky.social reporting a plethora of novel TIR-based immune signalling systems

www.biorxiv.org/content/10.6...

04.12.2025 06:31 β€” πŸ‘ 17    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

Congratulations to Dr Annis Newman ‼️
It was a pleasure to read Dr Newman’s PhD thesis - and then to spend this morning’s Viva discussing the elegant science she did in @drprernavohra.bsky.social’s group at @edinburgh-uni.bsky.social

01.12.2025 23:38 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Congratulations to Dr Annis Newman ‼️
It was a pleasure to read Dr Newman’s PhD thesis - and then to spend this morning discussing the elegant science she did in @drprernavohra.bsky.social’s group at @edinburgh-uni.bsky.social

01.12.2025 23:29 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Investigating the role of the Vi antigen in Salmonella pathogenesis. at University of Edinburgh on FindAPhD.com PhD Project - Investigating the role of the Vi antigen in Salmonella pathogenesis. at University of Edinburgh, listed on FindAPhD.com

If you’re interested in solving bacterial mysteries, this PhD project is for you!

www.findaphd.com/phds/project...

02.11.2025 18:07 β€” πŸ‘ 8    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0