Lingyin Li, PhD's Avatar

Lingyin Li, PhD

@lingyinli.bsky.social

Prof. at @stanford.edu & Core Investigator at @arcinstitute.org | Uncovering drug targets in innate immunity and developing therapeutics for cancer and autoimmunity | Mother of 2 | https://arcinstitute.org/labs/lilab

759 Followers  |  55 Following  |  3 Posts  |  Joined: 14.11.2024  |  1.3678

Latest posts by lingyinli.bsky.social on Bluesky

Stanford MSTP student Songnan Wang and I wrote a preview on Nan Yan's discovery of the immunotransmitter function of 2-5A in the dsRNA sensing. With two big fields emerging, we draw conceptual comparisons with the immunotransmitter cGAMP in the dsDNA sensing. authors.elsevier.com/a/1kuse3qNrU...

08.04.2025 17:00 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1
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At the AACR IO meeting in LA. Come say hi if you are here.

24.02.2025 18:15 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies Impaired cerebral glucose metabolism is a pathologic feature of Alzheimer’s disease (AD), with recent proteomic studies highlighting disrupted glial metabolism in AD. We report that inhibition of indo...

Exciting new discovery from colleagues @stanfordmedicine.bsky.social, astrocyte metabolism compromised by amyloid and tau oligomers leading to insufficient support for neurons. Possible new target for treating AD.

www.science.org/doi/10.1126/...

26.11.2024 17:31 β€” πŸ‘ 211    πŸ” 47    πŸ’¬ 4    πŸ“Œ 3

What a great piece of news so many years in the making. Congratulations Profs Monjie and Mackall.

14.11.2024 22:52 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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