Stephen Tait

Functionally dominant hotspot mutations of mitochondrial ribosomal RNA genes in cancer Nature Genetics - Analysis of 14,106 tumor genomes highlights recurrent mutations in mitochondrial ribosomal RNA encoded within the mitochondrial genome. Mutations occur at hotspot positions and...

Excited to share our latest work in collaboration with the @edreznik.bsky.social lab @mskcancercenter.bsky.social, where we describe functionally dominant mitochondrial DNA mutations in patient tumors. So, what is functional dominance in mitochondrial genetics, I hear you ask?

rdcu.be/eN1jm

03.11.2025 11:14 — 👍 66    🔁 23    💬 1    📌 6

Promotional graphic for a special issue of Disease Models & Mechanisms titled "In Vitro Models of Human Disease to Inform Mechanism and Drug Discovery." The left side of the image contains text announcing the call for papers, edited by Vivian Li, Austin Smith, and Joseph Wu, with a submission deadline of 3 November 2025. The right side features a vibrant, microscopic image of biological tissue or cell structures in vivid pink, blue, and yellow hues, representing the complexity of in vitro disease models. The design combines scientific detail with visual appeal to attract submissions for the issue.

Call for papers: In Vitro Models of Human Disease to Inform Mechanism and Drug Discovery

Deadline approaching: Monday 3 November 2025

journals.biologists.com/dmm/pages/in...

#Biology #Research #Disease #Discovery #Organoids #Tumours #Gastruloids #Assembloids

20.10.2025 14:25 — 👍 5    🔁 4    💬 0    📌 0

So, so sad.

02.04.2025 09:49 — 👍 3    🔁 0    💬 1    📌 0

Schedule of speakers at the 2025 FASEB Ferroptosis conference

Registration is open for our summer FASEB #Ferroptosis Conference July 27 - 31, 2025. We have a terrific line up of speakers and it's going to be amazzzing! Come join us for this historic first meeting! Please help us to spread the word. 🤩
shorturl.at/QA6T1

13.02.2025 06:27 — 👍 28    🔁 17    💬 2    📌 3

Super proud to have led this application with Dr Conchita Vens and showcase the amazing work done by @chrishalsey.bsky.social @mitosrus.bsky.social @scs-voice.bsky.social @cruk-si.bsky.social David Bryant and many many more over the last deacde

12.02.2025 14:40 — 👍 12    🔁 4    💬 0    📌 0

With two complete starter packs (in my profile), here is a 3rd one for the ever-growing metabolism community. Please contact me if you are working (prerequisite) on metabolism and want to be included here; there is still some space. I will keep updating it.

go.bsky.app/7Uwa6fb

07.01.2025 13:54 — 👍 31    🔁 15    💬 13    📌 0

Everyone at Aberdeen FC is deeply saddened to learn of the passing of Aberdeen born football legend Denis Law.

One of Scotland’s greatest ever players, his legacy will live on in the North-east.

Our thoughts are with his family and friends.

17.01.2025 20:23 — 👍 256    🔁 46    💬 2    📌 5

Kristopher Sarosiek's Faculty Website Researching Cell Death

We're looking for a hard working and ambitious postdoc to join our lab studying cell death in cancer, development, toxicology, neurodegeneration and beyond! We strive to maintain a diverse, inclusive and collaborative work environment.
Apply now at sarosieklab.org!

21.11.2024 10:50 — 👍 13    🔁 5    💬 0    📌 1