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Isabel saur

@izzysaurlab.bsky.social

Molecular Plant Microbe Interactions @ University of Cologne. Immunity, AVR, receptors, mildews, cereals .....terrible with typos πŸ€·β€β™€οΈ @izzysaur

607 Followers  |  556 Following  |  56 Posts  |  Joined: 15.11.2024  |  1.9101

Latest posts by izzysaurlab.bsky.social on Bluesky

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A conserved stripe rust effector elicits variable resistance responses in wheat Plant resistance (R) and pathogen avirulence (Avr) gene interactions are central to pathogen recognition and disease resistance in crops. However, functional characterisation of Avr effectors in Pucci...

Our first wheat stripe rust Avr effector story. It is a short one that points to suppressors in this pathosystem while we could not link this Avr effector to a described R gene. www.biorxiv.org/content/10.1...

03.08.2025 02:41 β€” πŸ‘ 14    πŸ” 9    πŸ’¬ 0    πŸ“Œ 1

Here comes the final version.
Congratulations Erika, Yasu, Ken, and all others involved!
@yasukadota.bsky.social @shirasulab.bsky.social

www.science.org/doi/10.1126/...

30.07.2025 19:37 β€” πŸ‘ 18    πŸ” 10    πŸ’¬ 0    πŸ“Œ 0

Our latest article is now online!
@PlantBiotechnologyJournal

Expression of Arabidopsis FLS2 in N. benthamiana confers responsiveness to Ralstonia flg22 and activation of anti-bacterial immunity
doi.org/10.1111/pbi....

By Meng Li, Yujiao Chen, and Yali Wei

26.07.2025 02:21 β€” πŸ‘ 33    πŸ” 16    πŸ’¬ 5    πŸ“Œ 0
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Conservation and divergence of UVR8-COP1/SPA-HY5 signaling in UV-B responses of Marchantia polymorpha Ultraviolet-B radiation (UV-B) poses a major challenge to all forms of plant life. The liverwort Marchantia polymorpha (Marchantia) serves as a key model organism to study signaling pathways and to in...

Happy to share this work we did together with @yuankeliang.bsky.social in @romanulm.bsky.social lab. We looked in detail at UVR8-mediated UV-B signaling in Marchantia and found some conserved functions but also a few surprises! #plantscience #marchantia #UVR8

17.07.2025 17:08 β€” πŸ‘ 18    πŸ” 12    πŸ’¬ 1    πŸ“Œ 0
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Starship giant transposons dominate plastic genomic regions in a fungal plant pathogen and drive virulence evolution Nature Communications - Giant transposons, known as β€˜Starships’, mediate horizontal gene transfer between fungal genomes. Here, Sato et al. show that Starships occupy genome regions...

πŸ“£ Happy to see the journal publication πŸ“„ of our work on Starships πŸš€ in Verticillium fungi: terrific work led by @yukiyosato.bsky.social
rdcu.be/exBSp

24.07.2025 10:40 β€” πŸ‘ 103    πŸ” 56    πŸ’¬ 4    πŸ“Œ 1

I am looking for a (bio)chemist to join the lab and help us making affinity-based probes for proteases! The project is truly interdisciplinary with a strong computational chemistry component, peptide synthesis and plant biochemistry!
Text me if interested and please spread the word!

14.07.2025 13:51 β€” πŸ‘ 23    πŸ” 39    πŸ’¬ 0    πŸ“Œ 0

@newphyt.bsky.social :-)

22.07.2025 06:31 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Warning: product placement….😬

Of course also thx to New Phytologist for the great sponsoring of the powdery mildew satellite meeting at #2025ISMPMI

And thx to @proteintech.bsky.social , I think a lot of us
use the products and also we do very much appreciate the goodies :-)

18.07.2025 15:28 β€” πŸ‘ 10    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

Ah come on everyone gets this confused and probably the lock was just too small to fit both 😹

18.07.2025 14:39 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Emergence of isochorismate-based salicylic acid biosynthesis within Brassicales | PNAS Salicylic acid (SA) is a major defense phytohormone. In Arabidopsis thaliana, the isochorismate (IC) pathway is the primary route for pathogen-indu...

I'm very happy that this paper is now published in PNAS!

Isochorismate-based salicylic acid biosynthesis appears to have emerged in the Brassicales after the divergence of C. papaya, likely within the timeframe between the divergence of B. maritima and R. odorata.

www.pnas.org/doi/10.1073/...

18.07.2025 07:52 β€” πŸ‘ 70    πŸ” 24    πŸ’¬ 4    πŸ“Œ 1

I tried but β€šIt was a mildewβ€˜ just doesnt work

18.07.2025 07:02 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Thx MPMI, thx powdery mildew crew!
For me it had bern many years to again see this great community and theirs great science. Wow things are moving fast!

Impossible to say bye to everyone bc it took 5 days already to say hello….

here a collective GOOD BYE #2025ISMPMI ! It was a blast (literally)

18.07.2025 06:14 β€” πŸ‘ 14    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Pseudomonas intra-genus competition determines the protective function of synthetic bacterial communities in Arabidopsis thaliana The plant microbiome can protect its host against detrimental bacterial strains. This study shows that competition among Pseudomonas bacteria in synthetic bacterial communities determines how well the...

Our paper on Pseudomonas intra-genus competition in SynComs on Arabidopsis roots is now out @plosbiology.org ! πŸŽ‰
If you want to chat about the story, visit poster 374 tomorrow, Thursday #2025ISMPMI

journals.plos.org/plosbiology/...

16.07.2025 19:11 β€” πŸ‘ 55    πŸ” 23    πŸ’¬ 2    πŸ“Œ 0
A woman speaking at a lectern with the MPMI logo

A woman speaking at a lectern with the MPMI logo

Final session at #2025ISMPMI:

@algazuccaro.bsky.social studies how endophytic fungi colonize plant roots. Do these fungi act as microbial gatekeepers?

Serendipita antagonizes barley pathogens while promoting plant growth. Key effectors from the fungus triggered by plants, but also other microbes.

17.07.2025 15:38 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 2    πŸ“Œ 0

Wow! How did you even manage to get a reservation for this large bunch! Well done :-)

17.07.2025 21:30 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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#2025ISMPMI has been great, so many connections made and re-established. I found this on the railway bridge.

17.07.2025 14:23 β€” πŸ‘ 62    πŸ” 13    πŸ’¬ 4    πŸ“Œ 1

One more week to apply for this exciting Professorship in Plant Sciences at Uni Halle! Join our vibrant plant research community 🌱

Info πŸ‘‰ wcms.itz.uni-halle.de/download.php...

@unihalle.bsky.social @snp2prot.bsky.social

17.07.2025 11:12 β€” πŸ‘ 19    πŸ” 26    πŸ’¬ 0    πŸ“Œ 1
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Mary wildermuth #2025ISMPMI gives the best introduction to the Powdery mildew fungus :)

17.07.2025 13:52 β€” πŸ‘ 12    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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www.biorxiv.org/content/10.1...
Up next at #2025ISMPMI @kseniakrasileva.bsky.social discussing work on protein language model for receptor engineering.

17.07.2025 08:34 β€” πŸ‘ 29    πŸ” 10    πŸ’¬ 0    πŸ“Œ 0

β€˜Even if the genes looks like it will be more durable, that is usually not the case-expose the gene to the pathogen and the pathogen will break it down’

17.07.2025 07:15 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Evans Lagudah at the last morning plenary of #2025ISMPMI discussing the potential of non-NLR / isolate-specific resistance genes (eg adult plant resistance genes) in terms of durability and broad specificity

17.07.2025 07:11 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Peter Dodds kicking off the crop resistance session at #2025ISMPMI : an Avr atlas for (rust) disease resistance!

16.07.2025 13:22 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Arabidopsis thaliana CELLOX1 limits fungal colonization in roots. Nice talk by Giulia Peruzzi at #2025ISMPMI, @ceplas.bsky.social

16.07.2025 09:58 β€” πŸ‘ 22    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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If you wanna dive into the world of #proteostasis and its role in plant immunity, visit @margotraffeiner.bsky.social poster (P-405) today. She discovered a novel proteotoxicity regulator (a protease with ubiquitin binding capacities) that plays a role in biotic and abiotic stresses! #2025ISMPMI

16.07.2025 09:34 β€” πŸ‘ 20    πŸ” 10    πŸ’¬ 0    πŸ“Œ 1
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#ISMPMI Martin Stegmann from Uni Ulm on the perception of CEP peptides, which were first described to play a role root nod nematodes. These days we know they are crucial phytocytokines & Martin demonstrates the function in immuniy

16.07.2025 09:16 β€” πŸ‘ 10    πŸ” 5    πŸ’¬ 0    πŸ“Œ 2
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mamp-ml: A deep learning approach to epitope immunogenicity in plants Eukaryotes detect biomolecules through surface-localized receptors, key signaling components. A subset of receptors survey for pathogens, induce immunity, and restrict pathogen growth. Comparative gen...

#2025ISMPMI πŸ“£ In silico screening of PRR-epitope interactions is now possible!

Here, we developed mamp-ml to predict their immunogenic outcomes without structural context. Let's accelerate engineering plant receptors for robust resistance! πŸš€πŸŒ± Small 🧡

www.biorxiv.org/content/10.1...

15.07.2025 23:28 β€” πŸ‘ 70    πŸ” 35    πŸ’¬ 1    πŸ“Œ 5

That was my bench too :-) but probably much later! Good to see Imre!

15.07.2025 13:32 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Now @manuelgonzalezfuen.bsky.social is on stage presenting his exciting project on p-bodies, and how bacteria utilize them to attenuate host translation #proteostasis #2025ISMPMI

15.07.2025 10:26 β€” πŸ‘ 17    πŸ” 6    πŸ’¬ 2    πŸ“Œ 0
A person giving a scientific talk showing a slide with varicose mutant plants and a workflow for mass spec from a TRADE pulldown

A person giving a scientific talk showing a slide with varicose mutant plants and a workflow for mass spec from a TRADE pulldown

Corinna Thurow is the last talk today before the free afternoon.

Verticillium effector (TRADE) interacts with host varicose protein (VCS). Used a forward screen to figure out insensitive mutants and identified a WIND1 transcription factor.
#2025ISMPMI

15.07.2025 11:12 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0

Wow nice you managed to get everyone together! 😍

15.07.2025 05:15 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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