Devin Teehan

Here is a blast from the past.
May the force be with you.

And may your vaccines keep you healthy and with long life.

Higher levels of antibiotic resistance are less competitive: the hidden ecological cost of no-metabolic cost resistance Antibiotic resistance is often assumed to be constrained by fitness costs that limit the spread of highly resistant strains. Yet, many resistance mechanisms – including enzymatic antibiotic degradatio...

Higher levels of antibiotic resistance are less competitive: the hidden ecological cost of no-metabolic cost resistance

bioRxiv from Peter Yunker

www.biorxiv.org/content/10.6...

Engineered vesicles enhance oral antibiotic absorption in proximal small intestine and mitigate gut dysbiosis
www.nature.com/articles/s41... @natcomms.nature.com

Spatial proximity dictates bacterial competition and expansion in microbial communities - Nature Communications Here, the authors show that immotile bacteria degrade antibiotics to alter their environment and facilitate nearby motile competitors to expand. As expansion proceeds, the immotile degrader is outcomp...

Spatial proximity dictates bacterial competition and expansion in microbial communities

@natcomms.nature.com by @esimsek.bsky.social et al from @lingchongyou.bsky.social

www.nature.com/articles/s41...

LONG RAMBLING EMOTIONAL THREAD:

It's World AIDS Day. Since the Administration has decided to keep it quiet, I'd like to share my introduction to AIDS.

I grew up in Seattle. My mom remarried a man who had a brother who was a King County Sheriff's Deputy. His name was Terry and he was gay. 1/x

Interactive AIDS Quilt The National AIDS Memorial, through a partnership with the AIDS Quilt Touch team, presents all 48,000 panels of the AIDS Memorial Quilt in an interactive experience People around the world can experie...

“The National AIDS Memorial, through a partnership with the AIDS Quilt Touch team, presents all 50,000 panels of the AIDS Memorial Quilt in an interactive experience so people around the world can experience the beauty of the Quilt and witness the love and stories stitched into each panel.”

AMR is moving through every ecological niche, including wildlife.
This #FEMSMicrobiolEcol review uncovers how animals act as reservoirs, pathways, and receivers of resistant bacteria and genes, reshaping the AMR landscape.

🔗 Learn more: buff.ly/86PDZNf

#AMRAwarenessWeek

Metagenomic editing of commensal bacteria in vivo using CRISPR-associated transposases Although metagenomic sequencing has revealed a rich microbial biodiversity in the mammalian gut, methods to genetically alter specific species in the microbiome are highly limited. Here, we introduce ...

Very excited to share our latest work in Science on metagenomic editing (MetaEdit) of the gut microbiome in vivo & directly modifying unculturable immune-modulatory SFB bug in the small intestine. 🦠🧬🛠️
www.science.org/doi/10.1126/...

I had the opportunity to review the work experience and skills of numerous people who were laid off or fired from public health jobs by Donald Trump.

I want every taxpayer to know that the US has lost an immeasurable number of the smartest, most experienced, and hardworking people on the planet.

Economic loss from the White House's NSF FY 2026 Proposed Budget

New from #SCIMaP - analysis of the White House’s Proposed FY 2026 National Science Foundation Budget.

Take-home: Slashing NSF by >50% will lead to ~$11 billion in economic loss and extensive job loss and reduced training opportunities in communities nationwide.

Report: osf.io/e8rnc

a 🧵

Me and explaining a figure to a group of people DO NOT go together real bad

For more information about the Friday night massacre at CDC, I wrote up an analysis of who got terminated and what that means for public health.

Grateful to @saveamericamvmt.bsky.social for supporting and amplifying. We are in really terrible trouble.

rasmussenretorts.substack.com/p/the-death-...

Rationale is quickly becoming my favorite and least favorite word

Is this thing still on

Eric Green was helping support our Tribal Colleges & Universities training in genomics. This is a loss at NIH.

My heart is just shattered for NIH as an institution. It represents what, in my view, is best about America:

A group of committed people working hard and creatively with one another to achieve important goals to help people across the country and around the world.

12/n

Oh you like microbiology? Name the ten species that comprise half of the bacteriology literature
www.biorxiv.org/content/10.1...