Eunchai Kang

🎓 Incredibly proud to have graduated today from the @uniofaberdeen.bsky.social University of Aberdeen.

Back in 2021, as a Clinical Assistant Professor on the verge of promotion to Associate—and then Full Professor within a few years—I faced a pivotal choice:

Deciphering cell-type-and temporally specific matrisome expression signatures in human cortical development and neurodevelopmental disorders via scRNA-seq meta-analysis - Nature Communications Human cortical development involves dynamic changes in matrisome gene expression across cell types and developmental stages. Here, authors show that these changes reveal links to neurodevelopmental di...

New research from University of Aberdeen neuroscientists shows how matrisome genes guide brain development and relate to neurodevelopmental disorders. @eunchaikang.bsky.social @uniofaberdeen.bsky.social
Read more: www.nature.com/articles/s41...

Heartfelt thanks to my PhD supervisor, Dr. @eunchaikang.bsky.social, and to my family, friends, and colleagues who supported me along the way.

Here’s to new beginnings—and to making a difference.
#Graduation #PhDJourney #LifelongLearning #Science #GrowthMindset #UniversityOfAberdeen

IL-17A Alters Human Cortical Development in a 3D Ex Vivo Model of Maternal Immune Activation Human brain development depends on the coordinated interaction of diverse cell types and extracellular matrix (ECM) components, which are essential for proper neurogenesis and cortical organization. E...

🚨 Maternal inflammation doesn’t just change the cellular makeup of the developing human cortex—it extensively remodels its extracellular matrix.
In this preprint, we report the effects of IL-17A, key cytokine in maternal inflammation, on developing human 🧠.
www.biorxiv.org/content/10.1...

Excited to attend this upcoming meeting on cortical development and hear from some of the leading voices in the field. I’ll also be presenting our work from @kangberglab.bsky.social on how maternal inflammation impacts early human cortical development.
Still time to register—don’t miss it!

Sincere thanks to Prof John Mason @johnomason.bsky.social and Dr Emilie Hollville for their expert examination and thoughtful discussion. 🧠👏 @aberdeenneuro.bsky.social @uniofaberdeen.bsky.social

🎓 Congratulations to Dr Do Hyeon Gim on a brilliant PhD defense! His thesis uncovers cell-type and temporal-specific matrisome expression signatures in human cortical development and neurodevelopmental disorders. Read it here: doi.org/10.1101/2025...

Deciphering Cell-Type and Temporal-Specific Matrisome Expression Signatures in Human Cortical Development and Neurodevelopmental Disorders via scRNA-Seq Meta-Analysis Human cortical development is a complex process involving the proliferation, differentiation, and migration of progenitor cells, all coordinated within a dynamic extracellular matrix (ECM). ECM plays ...

🧠 New preprint! Our meta-analysis of scRNA-seq data (37 donors, GWs 8–26) maps ECM dynamics in human cortical development, linking many genes to NDDs.

📄 Read more:https://www.biorxiv.org/content/10.1101/2025.02.24.639826v1

#Neuroscience #scRNAseq #ECM #Neurodevelopment #Preprint #metaanalysis

Proud of my first PhD student Muhammad @dr-assir.bsky.social who passed his viva! Great job! And thanks to Dr Theil and Dr Garden who gave valuable feedback.

Professor Simon Parson

A new multi-national study has found, for the first time, that people living with the neurodegenerative condition Spinal Muscular Atrophy (SMA) are at a higher risk of developing fatty liver disease which can have serious long-term health consequences. Find out more at www.abdn.ac.uk/news/23433/

Our first pre-print out in biorxiv. Read all about it! #neuroscience #Neurogenesis

YouTube video by NeuroStemLab How Scientists Grow Human Brain Cells to Uncover Neuroscience’s Biggest Secrets

Curious about how we grow minibrains in the lab? Watch my latest video to see how brain organoids are advancing our understanding of the human brain and revolutionizing neuroscience research. Dive in and explore the science behind these incredible models! youtu.be/xmiDiDY6yoY?...