Karina Xavier Lab

Two days of scientific discussion and networking will be followed by a day open to the public — reinforcing our commitment to sharing research with society.

Secure your ticket!
🔗 Get your ticket: fest.gimm.pt

🎟️ Early bird special rates

New PDRA position with @knightjar.bsky.social @coytelab.bsky.social & me

Community assembly processes in soil microbiomes with focus on bioinformatics and computational modelling of data from field and lab experiments

www.jobs.manchester.ac.uk/Job/JobDetai...

Klebsiella strain to protect against IBD gut infections A team of researchers led by Karina Xavier has uncovered a promising new live biotherapeutic agent that may redefine how the medical field approaches microbiota-based therapies.

New research led by @karinaxavierlab.bsky.social at 🇵🇹 @gimmfoundation.bsky.social demonstrates that a harmless strain of 🦠 #Klebsiella – discovered by chance in 🧫 laboratory experiments – can eliminate #infections and reduce gut inflammation in mouse models of inflammatory bowel disease. #IBD

And I also want to thank Carles Ubeda for the great collaboration a long the years

Great way to finish the year! Here showing that the amazing gut Microbiota Isolate - ARO112 can accelerate microbiota recovery after perturbations and protect against gut Inflammation. This work was possible given the hard and brilliant work of @vhrcabral.bsky.social and @aritaoliveira.bsky.social

Klebsiella ARO112 promotes microbiota recovery, pathobiont clearance and prevents inflammation in IBD mice Nature Communications - Here, the authors provide evidence of the biotherapeutic potential of Klebsiella ARO112 for gut inflammatory conditions by showing it accelerates pathobiont clearance and...

Thrilled to share that our new paper is out now in @natcomms.nature.com 🎉
Huge congrats to @vhrcabral.bsky.social and @karinaxavierlab.bsky.social on this major work.

We found that our Klebsiella ARO112 can break the antibiotic/inflammation cycle in an IBD model

Klebsiella ARO112 promotes microbiota recovery, pathobiont clearance and prevents inflammation in IBD mice Nature Communications - Here, the authors provide evidence of the biotherapeutic potential of Klebsiella ARO112 for gut inflammatory conditions by showing it accelerates pathobiont clearance and...

Great way to finish the year! Here showing that the amazing gut Microbiota Isolate - ARO112 can accelerate microbiota recovery after perturbations and protect against gut Inflammation. This work was possible given the hard and brilliant work of @vhrcabral.bsky.social and @aritaoliveira.bsky.social

Wrapping up the coolest Summer School on Host-Microbe Symbioses at @gimmfoundation.bsky.social Portugal! Over this course, I had 2min flash talks on my PhD work, presented 2 posters and designed group projects. Thank you @karinaxavierlab.bsky.social #Waldan Kwong and #Martin Blaser for the guidance.

Ecological management of the microbiota in patients with cancer Nature Reviews Clinical Oncology - This Review synthesizes the current understanding of host–microbiota dynamics in patients with cancer and proposes to integrate microbiota management...

Fresh from the press (from my brother Joao Xavier)

www.nature.com/articles/s41...

The pill that might be relieving your heartburn but killing your gut microbes Why drugs commonly used against heartburn harm your gut microbiome

Big thanks to scientific writer Libera Lo Presti for this great little piece on our recent work exploring how proton pump inhibitors (PPIs) and pH affect human gut microbes.
Check it out here: go.nature.com/4lf6jNk

Do people in the same household share strains when they have the same species?

How many cells transmit when a strain is shared?
Can strain composition be dynamic when species composition is stable?

We answer these and related questions for the facial skin microbiome in our latest paper.

🧵[1/10]

From Fellowship to Frontline: Camille Goemans’ Mission to Tackle Antibiotic Resistance – People – EMBO An interview with Camille Goemans, tenure-track assistant professor at the École Polytechnique Fédérale de Lausanne (EPFL) in Lausanne, Switzerland and former EMBO Postdoctoral Fellow

How the @embo.org postdoctoral fellowship helped me in developing my academic career... happy to see my profile featured on the EMBO website!
www.embo.org/people/from-...

Congratulations, Edith Heard, former EMBL Director General!

She was appointed a Companion of the Order of St Michael and St George in the 2025 King’s Birthday Honours List in the UK 👏

#kingshonours

www.embl.org/news/awards-...

Bacteria Talk each other? Yes, they do! Interested investigating how bacteria communication affects gut Microbiota community function, checkout our proposed PhD project and apply here gimm.pt/course/phd-p...

Call for our new PhD program is open. Come join one of our labs at Gulbenkian Institute for Molecular Medicine - Lisbon-Oeiras, Portugal. Help us spread the word

Call for Group Leaders - Join us at GIMM, 7 days till the deadline!

Genome duplication in a long-term multicellularity evolution experiment - Nature In the Multicellularity Long Term Evolution Experiment, diploid yeast evolve to be tetraploid under selection for larger multicellular size, revealing how whole-genome duplication can arise due to its...

1/46 Hey folks, we have a new paper out on the MuLTEE. Strap in and I’ll tell you the story of how this “little paper on polyploidy” turned into the most data rich paper our lab has produced, largely thanks to the leadership and work ethic of @kaitong25.bsky.social.

www.nature.com/articles/s41...

Great Microbiology meeting at the EMBL

Join our favorite microbiology meeting! Fantastic talks, poster sessions, new technologies, and all the hot areas of microbiology in a great environment - experts in cell & systems biology, microbiomes, environment & evolution, pathogenesis, phage & antibiotics
DON’T MISS abstract deadline, April 1

Vilcek Prizes for Creative Promise - Vilcek Foundation The Creative Promise Prizes are awarded to young immigrant professionals who have demonstrated outstanding achievement early in their careers.

More important now than ever before: vilcek.org/prizes/vilce...

Laila Partida-Martinez is the director and principal investigator at Cinvestav-Irapuato. She is interested in fungal-bacterial interactions, plant-microbe interactions, microbial ecology and natural products produced by microorganisms.

📢 Meet the speakers of the 2025 SymbNET Summer School on Host-Microbe Symbioses gimm.idloom.events/phd-summer-s... 👉 Know more about Laila: orcid.org/0000-0001-80...

Registrations until 28th March.

#SymbioSky #MicroSky

Follow @symbnet.bsky.social to hear about the speakers of our Symbnet Summer School on Host-Microbe Symbioses for PhD students - July 2025 Portugal

The researchers on a quest to protect the gut from antibiotics The crucial drugs can have unintended consequences. Innovative therapies could shield the microbiome from their effects.

Interesting story on challenges and promises of microbial engineering
www.nature.com/articles/d41...

Takema Fukatsu is a Prime Senior Researcher at the Bioproduction Research Institute, AIST. He uses experimental evolutionary approaches to study associated mechanisms and functions of microbial symbioses in insects.

📢 Meet the speakers of the 2025 SymbNET Summer School on Host-Microbe Symbioses gimm.idloom.events/phd-summer-s... 👉 Know more about Takema: bpri.aist.go.jp/en/staff/fuk...

@fkttkm.bsky.social

Registrations until 28th March.

#SymbioSky #MicroSky

Jewelna Akorli is a Principal Investigator and Wellcome Trust Intermediate Fellow at the University of Ghana. Her work centers on mosquito-associated endosymbionts and variations in vector competence in natural mosquito populations.

📢 Meet the speakers of the 2025 SymbNET Summer School on Host-Microbe Symbioses gimm.idloom.events/phd-summer-s... 👉 Know more about Jewelna: noguchi.ug.edu.gh/fellows/dr-j...

#SymbioSky #MicroSky

@berasymbionts.bsky.social

ASM stands firm in its commitment to diversity, equity and inclusion, as such efforts are critical to advancing the microbial sciences for everyone. Read our statement: asm.org/Press-Releas...

Present study, the feed incorporated Enterococcus faecium probiotic converts the precursor L-dopa to dopamine with high efficiency to produce significant amounts of dopamine within the gastrointestinal tract.

Postdoctor, 2 years, in predicting the evolution of antibiotic resistance The Department of Molecular Biology seeks a postdoctoral researcher who will work with forecasting and steering experimental evolution of antibiotic resistance. The employment is full-time for two yea

We have a 2-year postdoc position available in the Lind Lab at Umeå University, Sweden! Predicting and steering experimental evolution of antibiotic resistance in Pseudomonas aeruginosa. Reposts appreciated.
umu.varbi.com/en/?jobtoken...

PhD Summer School on Host-Microbe Symbioses 2025 Symbnet PhD Summer School on Host-Microbe Symbioses Gulbenkian Institute for Molecular Medicine (GIMM) & Católica Biomedical Research Centre (CBR) July 06...

Symbnet PhD Summer School on Host-Microbe Symbioses - Oeiras Portugal. Students from all over the world are eligible, we sponsor selected students. Please Repost!
gimm.idloom.events/phd-summer-s...