Sito Torres-Garcia

Specialized signaling centers direct cell fate and spatial organization in a mesodermal organoid model Stem cell–derived mesodermal organoids reveal how signaling centers guide cell fate and tissue organization.

🎉 Our deconstructed, stem-cell–based approach to studying signaling centers and limb-development cell types is out! 🥳 So nice to see it in its final form after the preprint— and huge thanks to the community for all the enthusiasm and interest since then!
www.science.org/doi/10.1126/...

If you’re into exciting science, you should definitely work with Can!

One enhancer can activate two endogenous genes simultaneously and across a TAD Boundary. Check out our new preprint.
www.biorxiv.org/content/10.1...

Thank you so much, Duncan 😊!

🙋🏻‍♂️ pls!

Haha a very nice one too!

Heterochromatin and RNAi Are Required to Establish CENP-A Chromatin at Centromeres Heterochromatin is defined by distinct posttranslational modifications on histones, such as methylation of histone H3 at lysine 9 (H3K9), which allows heterochromatin protein 1 (HP1)–related chromodom...

2 contenders here:
- www.science.org/doi/abs/10.1...
- www.nature.com/articles/nat...
Elegant experiments discovering beautiful mechanisms with functional impact