Julio Saez-Rodriguez's Avatar

Julio Saez-Rodriguez

@juliosaezrod.bsky.social

Computational Biologist, Head of research @ebi.embl.org, part-time Heidelberg University, codirector DREAM challenges. For group's activities, see @saezlab.bsky.social

1,306 Followers  |  141 Following  |  10 Posts  |  Joined: 20.11.2024
Posts Following

Posts by Julio Saez-Rodriguez (@juliosaezrod.bsky.social)

Preview
BioAIrepo: EMBL-EBI’s hub for life science AI models New EMBL-EBI repository helps researchers share and reuse machine learning models trained on life science data.

πŸ“’ We want your feedback on our new pilot project for sharing AI models in life science research.

Finding, reusing and citing machine learning models remains a major challenge in the life sciences.

BioAIrepo is here to help.

www.ebi.ac.uk/about/news/t...

26.02.2026 09:48 β€” πŸ‘ 15    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0
Post image

We’re recruiting new Research Group Leaders!
We offer:
πŸ”¬ Core funding
πŸ’» Access to world-leading infrastructure
πŸ‘©πŸ½β€πŸ”¬A network of world-leading scientists
…and much more.
Apply by 11 April: embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
#ResearchCareers #Bioinformatics @timcoorens.bsky.social @embl.org

25.02.2026 10:24 β€” πŸ‘ 20    πŸ” 20    πŸ’¬ 0    πŸ“Œ 1
Preview
Introducing BEACON: The Benchmarking, Evaluation, and Assessment Consortium for Science - Conscience We’re pleased to announce the launch of BEACON, a new open benchmarking consortium established through a collaborative effort by its founding partners from five organizations with deep expertise and p...

As AI is transforming science, robust benchmarks become essential.
BEACON is a global initiative advancing standards to evaluate AI using transparent benchmarks and #opendata.
#OpenScience #AI #DrugDiscovery @conscience-network.bsky.social @juliosaezrod.bsky.social

conscience.ca/news/introdu...

24.02.2026 13:15 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Preview
Research groups Our world-leading research groups focus on developing and applying computational and mathematical methods to a range of biological questions.

Join our faculty: ebi.ac.uk/research/gro... - our 9-year tenure nurtures our group leaders to go on to do great things: @virginieuhlmann.bsky.social @oliverstegle.bsky.social @moritzgerstung.bsky.social @teichlab.bsky.social @pedrobeltrao.bsky.social John Marioni

16.02.2026 07:38 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

we particularly welcome groups with a focus on (AI) methods, especially young female scientists. We evaluate by potential, not just your current track record. @ebi.embl.org is a great place to start a lab - speaking from experience

16.02.2026 07:38 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Do you want to pursue your ideas in computational biology independently, running your group in @embl.orgβ€˜s uniquely collaborative environment, beside world’s most comprehensive biomolecular data resources @ebi.embl.org in Genome Campus next to @sangerinstitute.bsky.social?
Apply to join us & share πŸ™

16.02.2026 07:38 β€” πŸ‘ 15    πŸ” 15    πŸ’¬ 1    πŸ“Œ 0

On March 4th, our @ricoramirez.bsky.social will share how we can currently study tissue remodelling with spatial transcriptomics data at a webinar from @training.ebi.embl.org.

This webinar series includes a great lineup of speakers. For free registration see link below ⬇️

12.02.2026 09:34 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Happy to share new work led by @miraburtscher.bsky.social, together with colleagues from @savitski-lab.bsky.social, @saezlab.bsky.social (shout-out to @martingarridorc.bsky.social), @zimmermannlab.bsky.social and others.

Original post + paper below! πŸ‘‡

12.02.2026 10:43 β€” πŸ‘ 9    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
Preview
DREAM Challenges - ISMB/ECCB 2025 - YouTube

Check the talks from @anshulkundaje.bsky.social @juliosaezrod.bsky.social @oldbap.bsky.social @mariabrbic.bsky.social ISMB 2025 special DREAM session on foundation models : youtube.com/playlist?lis...

01.02.2026 18:27 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1

New preprint from my team! led by @remitrimbour.bsky.social in collaboration with the @saezlab.bsky.social, we developped ReCoN a new method to model multicellular coordination and its underlying molecular mechanisms.

πŸ“œ Paper: lnkd.in/eJ8SfFNH
πŸ’» Code: lnkd.in/e-qx2iNp

29.01.2026 14:38 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
Post image

See πŸ‘‡ our new manuscript introducing SpaCEy, an explainable method for predicting clinical outcomes from spatial omics data 🧬

πŸ“„ Paper: www.biorxiv.org/content/10.6...
πŸ’» Code repo: github.com/saezlab/SpaCEy

17.12.2025 08:14 β€” πŸ‘ 15    πŸ” 10    πŸ’¬ 1    πŸ“Œ 1
Preview
Connecting AI to biology: Model Context Protocol Julio Saez-Rodriguez discusses how MCP servers are helping AI connect to life science databases, making AI a more reproducible tool for research.

AI holds huge promise for life science research. But unreliable answers currently limit its impact.

@juliosaezrod.bsky.social, Head of Research at EMBL-EBI, discusses how Model Context Protocol (MCP) servers are helping to change this.

www.ebi.ac.uk/about/news/p...
πŸ§¬πŸ’»

02.12.2025 11:26 β€” πŸ‘ 12    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
Preview
Postdoctoral fellow - Petsalaki Group - NetworkCommons Your group The Petsalaki, Saez-Rodriguez (EMBL-EBI) and KorcsmΓ‘ros (Imperial College) groups develop cutting-edge computational and AI approaches to unravel cellular signalling and gene regulation fro...

NEW: Postdoc with @epetsalaki.bsky.social @juliosaezrod.bsky.social and Tamas KorcsmΓ‘ros

Benchmark and integrate state-of-the-art network contextualisation methods, combining large-scale transcriptomics, proteomics, and single-cell data

Apply by 17 Dec

embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

26.11.2025 11:07 β€” πŸ‘ 4    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

πŸ“ Latest OmniPath paper is out now! ➑️ academic.oup.com/nar/advance-...

20.11.2025 10:09 β€” πŸ‘ 12    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
LinkedIn This link will take you to a page that’s not on LinkedIn

It was an honor to speak about Systems Biology of Kidney Disease at the American Society of Nephrology meeting www.youtube.com/watch?v=YLVs...
reflecting from my perspective as patient-scientist (www.nature.com/articles/s41...) & sharing work of @saezlab.bsky.social sp. within www.iganatlas.org

18.11.2025 15:05 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

πŸ“„ BioContextAI is now slightly updated and published @natbiotech.nature.com

➑️ www.nature.com/articles/s41...

07.11.2025 13:57 β€” πŸ‘ 5    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

Our revised consensus transcriptional patient map of human heart failure across patient cohorts and single-cell and bulk technologies is now published @natcomms.nature.com www.nature.com/articles/s41...

06.11.2025 12:10 β€” πŸ‘ 6    πŸ” 5    πŸ’¬ 1    πŸ“Œ 1
Post image

‼️ Deadline extension alert ‼️

The new abstract submission deadline for #EMBLCardioBiology is 10 November πŸ‘‰ https://s.embl.org/ncb26-01-bl

πŸ‘‰ Join experts pushing the frontiers of heart and vascular science
πŸ«€ Share your work and shape the future of cardiobiology
πŸ“œ Submit your abstract today!

17.10.2025 11:37 β€” πŸ‘ 2    πŸ” 4    πŸ’¬ 0    πŸ“Œ 2

Very happy to see this work finally online πŸ₯³

It was really interesting to write a short manuscript mixing method presentation & broader insights on data preprocessing. πŸ“

Thank you to my co-supervisors @cantinilab.bsky.social & @juliosaezrod.bsky.social for their feedback on this side work! 🫢

5/5

30.09.2025 12:23 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1
Post image

I'm presenting #CIRCE, a Python package to infer co-accessible DNA region networks 🧬

Based on #Cicero 's algorithm (Pliner et al.), it runs ~150x faster, processing an atlas of 700k cells in less than 40 min! ⛷️

Short paper: doi.org/10.1101/2025...
Code: github.com/cantinilab/CIRCE

1/5 ⬇️

30.09.2025 12:23 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
Preview
Current Vacancies Whether you're a scientist, IT specialist, accountant or administrator, you'll help us tackle the challenges of improving human health & biodiversity in the face of climate change on a global scal...

We are hiring a Postdoctoral Fellow in Computational Biology at EMBL-EBI (Cambridge, UK). Focus: methods to study cell–cell communication from sc/spatial omics data (building on LIANA+ and NicheNet), in collab with @yvansaeys.bsky.social VIB/Ghent.

Details & apply by 13/10/25: tinyurl.com/4shdw8dk

26.09.2025 10:16 β€” πŸ‘ 9    πŸ” 10    πŸ’¬ 0    πŸ“Œ 0
Post image

πŸ₯ Check out our new preprint on OmniPath, the prior knowledge resource for #SystemsBiology, and its brand-new OmniPath Explorer web app! πŸ₯³

πŸ“– Preprint: www.biorxiv.org/content/10.1...
πŸ” Explorer: explore.omnipathdb.org

OmniPath integrates 160+ resources for multi-omics analysis & modeling.

πŸ§Άβ¬‡οΈ

17.09.2025 13:09 β€” πŸ‘ 39    πŸ” 21    πŸ’¬ 1    πŸ“Œ 1
Post image

🚨 New preprint

We present an extended version of ScAPE, the method that won one of the prizes πŸ† in the @neuripsconf.bsky.social 2023 Single-Cell Perturbation Prediction challenge.

πŸ“„ preprint: doi.org/10.1101/2025...
🧬 code: github.com/scapeML/scape

19.09.2025 07:45 β€” πŸ‘ 30    πŸ” 7    πŸ’¬ 1    πŸ“Œ 1
Post image

Introducing ParTIpy, a python package for Pareto Task Inference that scales to large-scale datasets, including single-cell and spatial transcriptomics.
πŸ”— Manuscript: www.biorxiv.org/content/10.1...
πŸ’» Code: partipy.readthedocs.io

15.09.2025 08:39 β€” πŸ‘ 22    πŸ” 16    πŸ’¬ 1    πŸ“Œ 1
Preview
Welcome: Jess Ewald Jess Ewald, Research Group Leader at EMBL-EBI, uses cell profiling and AI to find and characterise chemical hazards to humans and ecosysystems.

Meet our newest Research Group Leader: Jess Ewald @ewaldlab.org β€¬πŸ‡¨πŸ‡¦

Jess’s group takes a multi-disciplinary approach to identify and characterise chemical hazards to humans and ecosystems, using cell profiling data, machine learning, and integrative data analysis.

www.ebi.ac.uk/about/news/p...

πŸ–₯️🧬

03.09.2025 09:07 β€” πŸ‘ 26    πŸ” 6    πŸ’¬ 0    πŸ“Œ 1
Preview
Welcome: Tim Coorens EMBL-EBI’s newest Research Group Leader is investigating how somatic mutations reveal the hidden histories of human cells.

Welcome @timcoorens.bsky.social β€ͺ β€¬πŸ‡³πŸ‡±, our new Research Group Leader.

Find out how Tim’s group is exploring using large-scale single-cell and spatial data to trace cell lineages, understand cancer origins, and uncover how mutations drive disease.

www.ebi.ac.uk/about/news/p...
πŸ–₯️🧬

12.08.2025 09:04 β€” πŸ‘ 48    πŸ” 10    πŸ’¬ 2    πŸ“Œ 0

@embl.org PhD programme just open - many interesting projects, including two with us @saezlab.bsky.social @ebi.embl.org - one on #host-microbiome interactions using #spatial omics, and one on #AI in #proteomics πŸ‘‡

02.09.2025 18:55 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Post image Post image

πŸ‘‹ Time to say goodbye to another one of our PhD students, @smuellerdott.bsky.social. She was working on the integration of phosphoproteomics and transcriptomics data and will now join the Computational Oncology Team at Merck. We wish her all the best for this new chapter! πŸš€ ✨

01.09.2025 05:34 β€” πŸ‘ 36    πŸ” 3    πŸ’¬ 1    πŸ“Œ 1
Post image

We present our MetaProViz #Rpackage for #metabolomics analysis & prior knowledge integration to generate mechanistic hypotheses on how metabolic changes affect metabolite classes, pathways & environment interaction

πŸ”—
www.biorxiv.org/content/10.1...

πŸ“¦
saezlab.github.io/MetaProViz/

🧡 Thread ⬇️

25.08.2025 07:07 β€” πŸ‘ 25    πŸ” 13    πŸ’¬ 2    πŸ“Œ 0

Glad to contribute to this collaborative community platform.
A case study shows MCP servers working together - combining BioContextAI Knowledgebase with our omnipath omnipathdb.org MCP (work in progress) to showcase interoperability. Looking forward to see how the ecosystem evolves!

31.07.2025 07:37 β€” πŸ‘ 11    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1