Jenelle Dorner

If you think research is expensive, try disease

@catgyoung.bsky.social

I’m wondering about any research demonstrating mitochondrial dysfunction in the MYH11 variant mice or in other models of MYH11 mutations? I’ve found minimal research suggesting mitochondrial dysfunction but thought that I would post here.

Before they paved paradise and put up a parking lot.

This is what democracy looks like. #NoKings

Philadelphia Pennsylvania: #NoKings is a huge success! Let’s go!

Chicago Illinois: #NoKings. You guys never stop to amaze me! Never stop you are wonderful!

Ten Things We Can All Do to Protect Democracy From Marc | The most common question I receive is how everyday citizens can help in the fight for democracy.

The most common question I receive is how everyday citizens can help in the fight for democracy. My advice, take the first step, start with something small and see what works for you. Here are ten things all of us can do. www.democracydocket.com/opinion/10-t...

Something to celebrate! 🎉 First approved drug for mitochondrial disease could pave way for more treatments. buff.ly/f6qmmWP

Cursive text reads “Fear only has the power we give it. Hope works the same way. -Bob Goff” It is written on a watercolor rainbow pattern background.

Fear only has the power we give it. Hope works the same way. -Bob Goff

Pride flag made up of flowers, from the Toronto Botanical Garden website.

Pride is in full bloom.

A sign in the background says New Hope church, God says homosexuality is in. In the foreground there are two men smiling holding the letter s that they've taken from the sign

Happy pride month ❤️🏳️‍⚧️🏳️‍🌈

A collage of four black-and-white photos showing people with disabilities and their supports in everyday settings. Top left: An older adult using a cane receives support from a caregiver. Top right: A young woman smiles and uses sign language. Bottom left: A therapist and child build a block tower together. Bottom right: A man in a wheelchair uses a tablet while talking with a coworker in a warehouse.

Think Medicaid is just for doctor visits? Think again.

- The wheelchair that helps someone get to work
- The personal aide that allows someone to live within their own home
- The therapy that helps a child speak their first words

Tell Congress NO CUTS today: ow.ly/rMYr50VV2v9

Detained on verge of U.S. citizenship, Mohsen Mahdawi speaks from Vermont prison Speaking to NPR in his first media interview since his detention, lawful permanent U.S. resident Mohsen Mahdawi finds peace in meditation and hopes "America will fulfill its promise."

Speaking to NPR in his first media interview since his detention, lawful permanent U.S. resident Mohsen Mahdawi finds peace in meditation and hopes "America will fulfill its promise."

We are the cosmos made conscious and life is the means by which the universe understands itself.

- Prof. Brian Cox

YouTube video by Doctor Clair Signs You May Have HSD (Hypermobility Spectrum Disorder) | Symptoms, Diagnosis & Management

Learn more about symptoms, diagnosis, and management of #HypermobilitySpectrumDisorder ( #HSD) in this video with Dr. Clair Francomano. youtu.be/93u8edKfbMQ?...

YouTube video by The Ehlers-Danlos Society 2023 Connecting The Dots between Autism, ADHD, Dyspraxia and EDS and HSD - Jane Gre...

It’s Autism acceptance & as the foremost charity with Patron @bendybrain.bsky.social & Chair @jgjanegreenmbe.bsky.social we’re proud to share our pioneering advocacy. Watch the @ehlersdanlos.bsky.social GLC keynote closing conference here: www.youtube.com/watch?v=McKt...
#AutismAcceptance #Autistic

US FDA suspends milk quality tests amid workforce cuts The Food and Drug Administration is suspending a quality control program for testing of fluid milk and other dairy products due to reduced capacity in its food safety and nutrition division, according to an internal email seen by Reuters.

they want you sick and preferably dead www.reuters.com/business/hea...

With CDC injury prevention team gutted, 'we will not know what is killing us' Workers who track data on car crashes, drownings, traumatic brain injury, falls in the elderly, and other perils lost their jobs. Advocates worry life-saving work will stop.

Workers who track data on car crashes, drownings, traumatic brain injury, falls in the elderly, and other perils lost their jobs. Advocates worry life-saving work will stop.

Hammock hugs are the best hugs.

Understanding #mitochondrial dysfunction in #Huntington's disease may guide potential treatment strategies. Targeting this dysfunction may help to slow disease progression and enhance the quality of life for individuals affected by Huntington's disease.
www.sciencedirect.com/science/arti...

Children with Long COVID have lung abnormalities, according to new research in Radiology. The small, prospective study included 54 participants, 27 with Long COVID and 27 matched controls. Researchers assessed them with an advanced MRI technique that measures both ventilation (flow of air into the lungs) and perfusion (blood flow). Children with Long COVID had worse ventilation and perfusion, and these readings were correlated with worse symptoms.

A new review in Biomolecules highlighted the overlap of immune dysfunction and metabolic dysfunction in myalgic encephalomyelitis (ME). “Mitochondrial dysfunction is a critical factor in the pathophysiology of ME/CFS,” the authors wrote, explaining that this dysfunction can cause a variety of problems in people with ME including fatigue and exercise intolerance. They wrote: “The further exploration of…immune–metabolic disruptions could unveil novel insights into ME/CFS pathophysiology, offering potential biomarkers for diagnosis and targets for therapeutic intervention.”

Another Long COVID clinical trial testing the drug Amantadine is currently recruiting. Amantadine is used to treat symptoms of Parkinson’s disease — researchers think it could help cognitive function in Long COVID. A second, separate trial, is still recruiting in Columbus, Ohio. The new single-blinded trial will enroll 30 participants in Dallas, Texas. Contact: brittany.wright@utsouthwestern.edu.

😷 Here’s what’s happening this week in #LongCOVID research: bit.ly/4btSNl3

💌 Sign up for our newsletter and get updates delivered directly to your inbox every week! thesicktimes.org/newsletter/

Mitochondrial complex I deficiency stratifies idiopathic Parkinson’s disease - Nature Communications Idiopathic Parkinson’s disease can be stratified according to the severity of neuronal respiratory complex I deficiency. The emerging disease subtypes show distinct molecular and clinical profiles.

Mitochondrial complex I deficiency stratifies idiopathic Parkinson’s disease | Nature Communications

1) CI deficient subtype - 1/4 of cases present widespread neuronal CI deficiency with non-tremor dominant motor phenotypes. And 👇
www.nature.com/articles/s41...

Prince Frederik of Luxembourg dies at 22 from rare mitochondrial disease The prince had PolG disease, a genetic mitochondrial disorder that prevents the body's cells from producing adequate energy.

The prince had PolG disease, a genetic mitochondrial disorder that prevents the body's cells from producing adequate energy.

🐶

ADHD research reveals effects of late diagnosis

Excited to be a researcher on this passion project as a late diagnosed neurodivergent woman with ADHD. It's been a privilege to interview women who shared their experiences and work with a team of neurodivergent researchers.

This is a glimpse of our findings so far.

news.csu.edu.au/latest-news/...