Marie Breau's Avatar

Marie Breau

@mariebreau.bsky.social

PI @ibps.bsky.social. Neurodevelopmental mechanics - Olfactory placode morphogenesis - Tissue interactions - Axon growth - ECM - Zebrafish https://www.ibps.sorbonne-universite.fr/en/research/development-adaptations-and-aging/mechanics-neuronal-development

953 Followers  |  842 Following  |  6 Posts  |  Joined: 23.11.2024
Posts Following

Posts by Marie Breau (@mariebreau.bsky.social)

Post image

Spread the word πŸ“’ & mark your calendars πŸ—“οΈ!!
The first edition of the Dev2A symposium series will be held on May 7, 2026.
πŸ‘‰Inspiring invited speakers & opportunities for selected talks and posters from submitted abstracts!!
➑️Registration: free but mandatory
➑️More information to come very soon

02.02.2026 13:18 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Rainbow shading of a confocal micrograph of a developing mouse neural tube. The protein actin is stained and colored in rainbow to indicate depth in the section.

Rainbow shading of a confocal micrograph of a developing mouse neural tube. The protein actin is stained and colored in rainbow to indicate depth in the section.

Happy #FluorescenceFriday! This is a maximum intensity projection of depth shaded actin (🌈) in a section from an E9.5 🐭 neural tube (NT). πŸ”¬ by postdoc @christinaadaly.bsky.social πŸ‘©β€πŸ”¬ πŸ§ͺ Image shows the floor plate and lumen of the developing NT.

#SciArt #DevBio #DevNeuro

10.10.2025 15:19 β€” πŸ‘ 122    πŸ” 26    πŸ’¬ 4    πŸ“Œ 2
Preview
E-cadherin mechanotransduction activates EGFR-ERK signaling in epithelial monolayers by inducing ADAM-mediated ligand shedding Epithelial stretching promotes the release of EGF receptor ligands that stimulate ERK activation.

A bit delayed, but excited to still share our latest paper, showing that intercellular forces transduced by E-cadherin activate EGFR-ERK signaling in epithelia by inducing EGFR ligand shedding! Mechanical and biochemical signals can act together within a single, linear cascade! tinyurl.com/mr9mj9j2

13.09.2025 18:04 β€” πŸ‘ 71    πŸ” 27    πŸ’¬ 4    πŸ“Œ 0

Katia took the initiative to start a Xenopus project in the lab a few years ago β€”and now her work is highlighted by Development! Huge congrats, Katia!

31.07.2025 10:39 β€” πŸ‘ 32    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0

#jobAlert We are hiring! If you like #imaging ,gene regulation and a dynamic group please apply. We are looking for a research assistant with a master degree and prior experience in academia.

28.07.2025 16:11 β€” πŸ‘ 27    πŸ” 24    πŸ’¬ 0    πŸ“Œ 1
Video thumbnail

Our paper is now published! The first encounter of a forming organism with bacteria reveals that innate immunity initiates in epithelial cells of early embryos, even in humans. www.cell.com/cell-host-mi...
made in @ibmb-csic.bsky.social @csic.es @idibell.bsky.social 1/9

19.06.2025 18:27 β€” πŸ‘ 14    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
Preview
FlyBase funding squashed amid Harvard grant terminations The team behind the Drosophila genetics database is now requesting donations from labs to keep the resource afloat.

FlyBase, a crucial resource for drosophila research, has lost its funding because its grant is awarded to Harvard. The team is scrambling to find other sources of funds, including donations from labs. Read more: www.thetransmitter.org/community/fl... @flybase.bsky.social

04.06.2025 21:11 β€” πŸ‘ 36    πŸ” 47    πŸ’¬ 2    πŸ“Œ 5

If you’ve ever wondered how those intricate gill structures emergeβ€”and how gills develop throughout a zebrafish’s lifespanβ€”check out my new preprint!
We dive into the development of gills and their vasculature in detail.
Huge thanks to @vlecaudey.bsky.social for the support🐟

#zebrafish #microscopy

05.06.2025 07:51 β€” πŸ‘ 40    πŸ” 11    πŸ’¬ 3    πŸ“Œ 2
Preview
Development of the zebrafish anterior lateral line system is influenced by underlying cranial neural crest The mechanosensory lateral line system of aquatic vertebrates comprises a superficial network of distributed sensory organs, the neuromasts, which are…

It's online! Happy to have contributed to this publication by @vishruthvenkat.bsky.social @vprincelab.bsky.social #DevBio @devbiol.bsky.social on the development of the #zebrafish anterior lateral line and the tissue-tissue interactions that shape it www.sciencedirect.com/science/arti...

02.06.2025 08:52 β€” πŸ‘ 74    πŸ” 9    πŸ’¬ 5    πŸ“Œ 0
Video thumbnail

What is buckling, and why is it relevant in understanding epithelial morphogenesis? 🧐

I am @onenimesa.bsky.social and I will share some papers to understand this aspect of #EpithelialMechanics

25.05.2025 13:41 β€” πŸ‘ 25    πŸ” 11    πŸ’¬ 1    πŸ“Œ 4
Preview
Direct measurements of active forces and material properties unveil the active mechanics of early embryogenesis Despite progress in probing tissue mechanics, direct long-term measurements in live embryonic epithelia are lacking. This limits our understanding of amniote embryonic morphogenesis, which takes place...

πŸš¨πŸ“£ New preprint alert!
Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos!
A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social
πŸ“„ www.biorxiv.org/content/10.1...
#devbio #mechanics

12.05.2025 14:01 β€” πŸ‘ 84    πŸ” 34    πŸ’¬ 1    πŸ“Œ 3
Post image

Ever wondered how organs take shape? Join us to find out!
The Organ Mechanobiology Lab @ncbsbangalore.bsky.social is recruiting Graduate Trainees. Perfect for final-year students curious about tissue mechanics, development & cell biology.
Check out the ad below πŸ‘‡ Please RT! ThanksπŸ™

10.04.2025 09:59 β€” πŸ‘ 21    πŸ” 16    πŸ’¬ 2    πŸ“Œ 0
Left: Expression of Notch3 (white) detected by whole mount RNAscope ISH in an E8.5d wild-type embryo, shown in frontal views (top, cranial part of the embryo) and transverse section (bottom). Filled and empty arrowheads point to high and low expression, respectively. Right: Segmentation of the cardiac region in 3D images, to quantify gene expression in the left (white) or right (yellow) heart field. The heart tube is colored in red. Somites are outlined by white dotted lines. Expression of Notch3 within the segmented second heart field is extracted in the right panel.

Left: Expression of Notch3 (white) detected by whole mount RNAscope ISH in an E8.5d wild-type embryo, shown in frontal views (top, cranial part of the embryo) and transverse section (bottom). Filled and empty arrowheads point to high and low expression, respectively. Right: Segmentation of the cardiac region in 3D images, to quantify gene expression in the left (white) or right (yellow) heart field. The heart tube is colored in red. Somites are outlined by white dotted lines. Expression of Notch3 within the segmented second heart field is extracted in the right panel.

Creating an asymmetric heart: @tbonnely.bsky.social @audreydsg.bsky.social @meilhacsigolene.bsky.social &co identify Notch3 as a novel asymmetric factor in lateral plate mesoderm that acts as a genetic modifier of NODAL to regulate heart morphogenesis @plosbiology.org πŸ§ͺ plos.io/42q6H4L

01.04.2025 13:39 β€” πŸ‘ 7    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Post image Post image

Are postdocs the rarest species, or is it just me? We have two funded positionsβ€”apply now and join us on these exciting projects! #zebrafish #zebrafishcareers #iPSC #devbio #regeneration

31.03.2025 19:37 β€” πŸ‘ 23    πŸ” 22    πŸ’¬ 1    πŸ“Œ 1

The Cell Dynamics lab @Dev2A-IBPS, Paris, is now on BlueSky! We love cytoskeletal movies (especially actomyosin), nice microscopy and C. elegans.

@dev2a-lab.bsky.social @ibps.bsky.social

Transferred from twitter using ➑️ OpenPortability.org

26.03.2025 08:49 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Post image

The Paris-Saclay Institute of Neuroscience @neuropsi.bsky.social has launched a call for new group leaders. Please spread the word!
deadline May 30
neuropsi.cnrs.fr/wp-content/u...
@cnrs.fr @univparissaclay.bsky.social

18.03.2025 07:44 β€” πŸ‘ 9    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
Preview
Science under siege: protecting scientific progress in turbulent times As Editors-in-Chief of The Company of Biologists' journals, we have been watching with growing concern the policy changes in the United States of America (USA) and the challenges that these are creati...

Science under siege: protecting scientific progress in turbulent times

journals.biologists.com/dev/article/...

13.03.2025 13:06 β€” πŸ‘ 79    πŸ” 44    πŸ’¬ 2    πŸ“Œ 2
Video thumbnail

Stoked to present our latest, superbly led by Chris et al & @torres-sanchez.bsky.social We tackled a fundamental problem – how tissues are patterned during development – found that geometry-constrained ECM fractures pattern the myocardium in the vertebrate heart 1/n www.biorxiv.org/content/10.1...

10.03.2025 02:43 β€” πŸ‘ 159    πŸ” 60    πŸ’¬ 5    πŸ“Œ 6
Post image

What do star fish, snowflakes, and even cells have in common?

I am @juliaeckert.bsky.social and I would like to take you on a journey into the field of soft matter and give you a brief overview of experimental observations on symmetries in biological systems. #EpithelialMechanics

01.03.2025 07:02 β€” πŸ‘ 44    πŸ” 19    πŸ’¬ 1    πŸ“Œ 1
Post image

Registration for the next GdR AQV days is now open until April 18th. The conference will take place in Sète - May 26th to 28th. aqv-days-2025.sciencesconf.org
There are many slots for oral communication. Come and join the French biophysics community!

19.02.2025 13:24 β€” πŸ‘ 13    πŸ” 16    πŸ’¬ 0    πŸ“Œ 4
Preview
Rho/Rok-dependent regulation of actomyosin contractility at tricellular junctions restricts epithelial permeability in Drosophila Cell vertices integrate forces in epithelia and play key roles in regulating barrier function. Jacobs etΒ al. show that modulation of actomyosin contractility at cell vertices controls tricellular junc...

Our new paper by @theajacobs.bsky.social in @currentbiology.bsky.social shows how relaxation of tension, rather than active actomyosin-based force, allows opening of cell #vertices to increase #epithelial permeability shorturl.at/Wnb2n
@sfb1348.bsky.social @uni-muenster.de

17.02.2025 16:01 β€” πŸ‘ 56    πŸ” 14    πŸ’¬ 1    πŸ“Œ 2

Beautiful! What’s the staining?

14.02.2025 16:50 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Do you want one of the most influential jobs in dev bio?

Would you like to work with the best group of editors & publishing professionals in the business?

Are you interested in leading the premier not for profit community focussed journal in the field?

Come be Development's next Executive Editor

14.02.2025 08:16 β€” πŸ‘ 30    πŸ” 32    πŸ’¬ 2    πŸ“Œ 1

My PhD paper is now online!
doi.org/10.1016/j.cu...
Big thanks to @mongeralab.bsky.social, K. Guevorkian and O. PourquiΓ©!
See the tweetorial below ‡️

28.01.2025 17:12 β€” πŸ‘ 42    πŸ” 10    πŸ’¬ 5    πŸ“Œ 0
Post image

πŸ””πŸ“’ Next event is fast approaching, so here is the complete program for next week's "Advances in Mechanobiology" session. @drsarahboyle.bsky.social @carstenschulte4.bsky.social @mathildemathieu.bsky.social Moderator: @ccstorytime.bsky.social Info: themeshwork2020.wixsite.com/info/up-comi...

28.01.2025 10:30 β€” πŸ‘ 10    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0
Post image

Announcing this upcoming conference:

GASTRULATION RELOADED:
Developing, engineering, and evolving the body plan

Join us as we explore the latest research on gastrulation and axis formation/elongation, featuring common, exotic, and synthetic embryos!

πŸ“… 14–17 October 2025
πŸ“ Paris, France

28.01.2025 08:14 β€” πŸ‘ 54    πŸ” 29    πŸ’¬ 3    πŸ“Œ 0
Post image

🚨 Postdoc wanted 🚨

Ever wondered how mechanical forces shape the heart tube during embryogenesis?…

I am looking for a postdoc with a background in developmental biology or biophysics to investigate this new topic as part of an ANR-JCJC πŸš€πŸ”¬

Don’t hesitate to contact me πŸ€“πŸ”—

27.01.2025 17:07 β€” πŸ‘ 23    πŸ” 19    πŸ’¬ 0    πŸ“Œ 1
Preview
Physiology: Modern Cell Biology Using Microscopic, Biochemical and Computational Approaches | Marine Biological Laboratory This course is at the forefront of new tools β€” molecular, computational, biophysical β€” as it prepares students to tackle emerging biological questions.

The deadline to apply for the MBL Physiology course is fast approaching, January 27th! Consider applying to this amazing, life-changing research discovery experience in Woods Hole! www.mbl.edu/education/ad...

19.01.2025 20:17 β€” πŸ‘ 45    πŸ” 34    πŸ’¬ 0    πŸ“Œ 6
Post image

#MiFoBio2025

The autumn microscopy school by @gdrimabio.bsky.social will take place from 10th to 16th October 2025.

The call for workshops to share pratical knowledges is open till 31/01 ateliers-mifobio.fr

We'll bring stuff as usual, stay tuned !

More information πŸ‘‰ linktr.ee/gdrimabio

20.01.2025 11:26 β€” πŸ‘ 13    πŸ” 7    πŸ’¬ 1    πŸ“Œ 2
Post image

Yamini @yamini-ravichan.bsky.social changed the topology of Hydra to show that actin orientational defects of Hydra induce the full program of head regeneration: www.science.org/doi/10.1126/...
Mechanics controls development! Thanks to Dan Pearce, Karsten Kruse, Matthias Vogg & Brigitte Galliot.

20.01.2025 07:19 β€” πŸ‘ 72    πŸ” 30    πŸ’¬ 3    πŸ“Œ 4