Prajna Hebbar

Atkinson Hyperlegible Font - Braille Institute Read easier with Atkinson Hyperlegible Font, crafted for low-vision readers. Download for free and enjoy clear letters and numbers on your computer!

periodic reminder of the existence of Atkinson Hyperlegible, a free font available from the Braille Institute designed to improve readability for people with low vision

I use it in talks because it's pretty and also because, as an audience member, I am perpetually squinting at people's slides

17.11.2025 04:19 — 👍 652    🔁 324    💬 20    📌 20

As the Moon eclipsed the Sun on 8 April 2024, birds like these rock pigeons (Columba livia) took note.

As the Moon eclipsed the Sun on 8 April 2024, birds took note.

Leveraging nature’s own experiment, scientists and the public joined forces to show how different species responded to sudden midafternoon darkness followed by a new “dawn.” Learn more this week in Science: https://scim.ag/48WbhLL

09.10.2025 18:05 — 👍 87    🔁 27    💬 3    📌 4

🦒Long read giraffe is out!🦒
Mapping long reads to pangenome graphs is ~10x faster than with GraphAligner, with veeery slightly better mapping accuracy, short variant calling, and SV genotyping than GraphAligner or Minimap2

02.10.2025 06:28 — 👍 42    🔁 22    💬 1    📌 0

Best practices for improving alignment and variant calling on human sex chromosomes Sex chromosome complement is the largest karyotypic variation observed in humans. X and Y chromosomes were once a pair of homologous autosomes. Although chromosome X and Y differentiated from one anot...

Our work looking at the effects of using autosomal assumptions for calling variation on X and Y. We used simulated data to compare to a ground truth.

Tldr: Accurate ploidy is important for reducing false positives; appropriate alignment reduces false negatives.

www.biorxiv.org/content/10.1...

07.05.2025 13:28 — 👍 26    🔁 13    💬 0    📌 0

The human pangenome continues to grow and improve! Release 2 is here! Click through for the details, but this is a pretty amazing dataset including not just the phased assemblies, but PacBio HiFi, ONT Ultralong, Dovetail/Illumina Hi-C, PacBio Kinnex, and Illumina WGS for all samples

12.05.2025 13:52 — 👍 82    🔁 36    💬 0    📌 0

📢 HPRC Release 2 is here!

Now with phased genomes from 200+ individuals, a 5x increase from Release 1.

Explore sequencing data, assemblies, annotations & alignments in our interactive data explorer ⬇️:

humanpangenome.org/hprc-data-re...

12.05.2025 13:14 — 👍 37    🔁 28    💬 0    📌 3

Complete sequencing of ape genomes - Nature Complete sequences of chromosomes telomere-to-telomere from chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran orangutan and siamang provide a comprehensive and valuable resource for future evol...

Our primate T2T paper came out in Nature yesterday! It was a huge effort and I'm so grateful that I got the opportunity to work with this amazing group of scientists over the first two years of my PhD!
www.nature.com/articles/s41...

10.04.2025 21:59 — 👍 24    🔁 9    💬 0    📌 0