Understanding the clinical utility of circulating tumor cells (CTCs) and future innovations is crucial to incorporating CTCs into the clinical management of #ProstateCancer.
Learn more from Drs. Sophia Abusamra, @lambalastair.bsky.social, and co-authors! 💡
📚 https://go.nature.com/4pLXZGq
Great #WhiteboardTalk from @YoussefArafat.bsky.social
Exciting use of #ImagingAI #CNN to detect morphol features of metastatic clones in #ProstateCancer
Key elements:
•Visium spots annotated for histo & clone
•Careful patch selection
•Incl TME as 'reflection'
#SPACE_Study
#CEV @qmbci.bsky.social
Awesome talk from Phil Jones @sangerinstitute.bsky.social on mutant clones in non-malignant tissue
Trillions of somatic mutations through lifetime incl skin, gut, bladder, breast, prostate, even neurons & vessels...yet vast majority don't transform
#OxCode25 #OxCodeSymp25
@oxfordcancer.bsky.social
Great talk from Ros Eeles at #OxCodeSymp25 @oxfordcancer.bsky.social
Super summary of #IMPACT_Study & why #NSC recommended #ProstateCancer screening for #BRCA men
#EarlyDetection
@francoiseshowe.bsky.social
@sarahblagden.bsky.social
@alexander-colton.bsky.social
@leedham-simon.bsky.social
Calling cancer data scientists! 📊 💽 🧮
We have a number of open positions in our core facility @icr.ac.uk These are bioinformatician staff scientist like roles to work on exciting single cell, spatial & other genomics data from across our Institute. A PhD is required. jobs.icr.ac.uk/vacancies/13...
Nice #LightningTalk from @maxbeesley.bsky.social as part of #PPCG 2025 meeting
Using @10xgenomics.bsky.social #Visium & #inferCNV to spatially profile clonal heterogeneity & metastasis in #ProstateCancer
#SPACE_Study
@Pinkykotecha.bsky.social
@thineskrishna.bsky.social
@sandyfigiel.bsky.social
Real treat to hear Ros Eeles explain rationale for genetic risk in #ProstateCancer screening.
A few key observations
•~50% of genetic risk still unknown (N.B. was 95% 10 yrs ago)
•difference between common (RR x2) and rare (RR 5-10x) variants
•Most RR refers to any PCa NOT lethal disease
#PPCG
Great work from @maxbeesley.bsky.social in his first #WhiteboardPresentation to assembled @qmbci.bsky.social #CEV!!
#ClonalEvolution
#SpatialBiology
#SPACE_Study #ProstateCancer
@mcclellandlab.bsky.social @ciccarellilab.bsky.social
Great to be at @kingscollegelondon.bsky.social #SpatialBiology Day in Robens Suite atop #GuysTower
Exciting to see critical mass of spatial tech, bioinformatics, biobanking, metallomics expertise and more
@habkcl.bsky.social
@10xgenomics.bsky.social
New CRUK Post-doc position in our group. #mutationalorder #multiomics #cancer.
my.corehr.com/pls/uoxrecru...
We are looking for our next PhD student to join us 🤩 www.mcclellandlab.com to understand cancer radiation therapy's impact on DNA damage repair and chromosomal instability. Prestigious funding from CRUK RadNet. Please contact me informally - deadline 5th Nov! crukradnet.colcc.ac.uk/phd-students...
02.10.2025 15:49 — 👍 17 🔁 9 💬 1 📌 1
Really enjoyed 1st Faculty Retreat for @qmbci.bsky.social Centre for Cancer Evolution #CEV PIs
Great chance to share visions for our groups alongside needs/aspirations/collabs
@ciccarellilab.bsky.social @mcclellandlab.bsky.social
@mirjana-efremova.bsky.social
Alex W, Michelle L, Ben W, Stuart McD
Come and join us at the Barts Cancer Institute @qmbci.bsky.social ! Our medical school, part of Queen Mary University of London @qmulfmd.bsky.social is hiring 10 professors!! www.veredus.co.uk/job/job-747a/. Contact me for a chat if interested.
01.10.2025 07:34 — 👍 20 🔁 8 💬 1 📌 1
Our first Centre for Cancer Evolution PI retreat! A wonderful day at Goodenough House discussing science, strategy and forging new collaborations @qmbci.bsky.social
01.10.2025 12:00 — 👍 7 🔁 3 💬 0 📌 0
•Are you a data scientist / bioinformatician?
•Interested in #DeepLearning applied to #SpatialBiology?
•Do you want to transform #ProstateCancer clinical decision-making?
Based @QMBCI.bsky.social
Apply here!! 👇 (closing date 20th May)
qmul-jobs.tal.net/vx/candidate...
#SPACE_Study #Organscale
Really loved @10xgenomics.bsky.social session @theaacr.bsky.social #AACR25 #SpotlightPresentation by Jingxian Liu on Tumour Evolution & Clonal detection using Visium spatial tech.
Can't wait to set up some collaborative conversations with the Ding Lab @washumedicine.bsky.social!
@qmbci.bsky.social
Brilliant session focused entirely on spatial multiomics @theaacr.bsky.social #AUA25
Well said @tanevski.bsky.social "Cancer is a spatial disease-spatialomics is the future of cancer science"!
Wonderful composite spatial data from Linghua Wang @mdanderson.bsky.social
www.nature.com/articles/s41...
Really enjoyed this deep dive into intratumoural immune archetypes from Matt Krummel
#AACR25 @TheAACR.bsky.social
Loved this video on T Cell vs Dendritic Cell interacting
#IntratumouralHeterogeity
#ClonalEvolution
#ReactiveImmunity
Join us in welcoming Alastair Lamb (@lambalastair.bsky.social) to the BCI @qmulfmd.bsky.social. Dr Lamb will launch the next phase of his research into #prostatecancer, supported by a new £1.6m grant from @cancerresearchuk.org
📰 Read more: www.bci.qmul.ac.uk/general-news...
🧪 #medsky #oncosky
Welcome to the Faculty, @lambalastair.bsky.social
03.04.2025 12:11 — 👍 2 🔁 1 💬 0 📌 0Few teasers here from our breaking news GU Cast yesterday on TRANSLATE trial #eau25 @lambalastair.bsky.social and team
24.03.2025 07:30 — 👍 3 🔁 1 💬 1 📌 0
Three people posing for a photograph. The outer two holding up certificates.
Congratulations to BJUI Global Prize winners Arthur Yim and Matthew Alberto for their #OpenAccess paper 'Near-infrared spectroscopy as a novel method of ex vivo bladder cancer tissue characterisation', presented today at #USANZ25
doi.org/10.1111/bju....
Great talk from @thineskrishna.bsky.social on #RadioSpatialGenomics & machine learning approaches to #ProstateCancer risk stratification, fusing spatial tissue data w high quality #mpMRI
@cancerresearchuk.org #ClinicalResearchMeeting
#SPACE_Study
@ndsurgicalsci.bsky.social
@oxfordcancer.bsky.social
Good to be involved in the @cancerresearchuk.org #ClinicalReseachers meeting at @rcn.org.uk Cavendish Sq.
Great opportunity to meet other #ClinicianScientists, network & discuss high quality science.
@thineskrishna.bsky.social @charlesswanton.bsky.social
@clareturnbull.bsky.social
Nice talk on #SpatialProteomics from @coscialab.bsky.social at #FoG2025 @fogenomics.bsky.social
Essential to unlock phenotype & prelude to biomarker discovery
•Are you a data scientist/bioinformatician/computational biologist?
•Are you interested in #SpatialGenomics?
•Do you want to apply your skills to big questions in #ProstateCancer?
Apply here!! 👇 (closing date 12th Feb)
qmul-jobs.tal.net/candidate/so...
#SPACE_Study #Organscale @qmbci.bsky.social
Really enjoyed @mirjana-efremova.bsky.social talk on phenotypic plasticity in #ColorectalCancer
Super clear explanation of role of key genes ( #LRIG1 etc) in cell switch
@qmbci.bsky.social
@ciccarellilab.bsky.social
@drtanyasoliman.bsky.social
@mcclellandlab.bsky.social
@sibucz.bsky.social
Cool to be at #FoG2025 @fogenomics.bsky.social
A bit more #SpatialGenomics content this year which is great!
Surprise visit from #Darth & #Chewbacca!
@ciccarellilab.bsky.social @mirjana-efremova.bsky.social
@karlsmithbyrne.bsky.social
@qmbci.bsky.social
@omaiques.bsky.social
2. Nice data. One again show outcomes from #prostatecancer. But avg. age 75 in HIFU cohort and 50% had Gleason 6. Overtreatment common - albeit with less morbid Rx. Confirm need for RCTs @londonprostate1.bsky.social @ip-london.bsky.social @euplatinum.bsky.social @ox.ac.uk @lambalastair.bsky.social
10.01.2025 08:32 — 👍 3 🔁 1 💬 0 📌 0
@danberney.bsky.social
V cool to be starting first proper day @QMBCI.bsky.social Charterhouse Sq! Thanks to Francesca C & Nitzan Rosenfeld for taking me on as Group Leader in Centre for Cancer Evolution🧬. And to Guys Urology for making it work🙏
Looking forward to rebuilding #SPACE_Study team here - recruiting soon!
