bioRxiv Molecular Biology

Diurnal plant and Rhizophagus irregularis transcriptional patterns are linked to shifts in cassava tissue partitioning in the field https://www.biorxiv.org/content/10.1101/2025.10.08.681086v1

The phage shock protein response of Listeria monocytogenes influences tolerance to the multipeptide bacteriocin garvicin KS https://www.biorxiv.org/content/10.1101/2025.10.08.681093v1

A microfluidics-based platform enables discovery of gametogenicrejuvenation factors in Saccharomyces cerevisiae https://www.biorxiv.org/content/10.1101/2025.10.07.681065v1

The 9-1-1 complex protects ssDNA gaps in BRCA2-deficient cancer https://www.biorxiv.org/content/10.1101/2025.10.07.680950v1

Opposing CTCF and GATA4 activities set the pace of chromatin topology remodeling during cardiomyogenesis https://www.biorxiv.org/content/10.1101/2025.10.07.680441v1

Inhibition of PfCLK3 a master regulator of malaria parasite RNA-splicing provides the basis for a radical cure for malaria https://www.biorxiv.org/content/10.1101/2025.10.07.680601v1

An AGO2 adaptor expands the functional and evolutionary reach of microRNA targeting https://www.biorxiv.org/content/10.1101/2025.10.07.680889v1

Frataxin depletion leads to decreased soma size and activation of AMPK metabolic pathway in dorsal root ganglia sensory neurons https://www.biorxiv.org/content/10.1101/2025.10.07.680891v1

EXPLICIT CORRECTION OF SEVERELY NON-UNIFORM DISTRIBUTIONS OF CRYO-EM VIEWS https://www.biorxiv.org/content/10.1101/2025.10.07.680880v1

Environmental Regulation of Toxin Production in Bacillus anthracis https://www.biorxiv.org/content/10.1101/2025.10.02.679957v1

Single-cell RNA-seq using UltraMarathonRT expands theknown transcriptome https://www.biorxiv.org/content/10.1101/2025.10.06.680646v1

Long-read Sequencing of Nascent RNA from Budding and Fission Yeasts https://www.biorxiv.org/content/10.1101/2025.10.06.680282v1

ER oxidoreductin-1α and unfolded protein response as sex-dependent drivers of cardiorenal dysfunction in experimental autoimmune encephalomyelitis https://www.biorxiv.org/content/10.1101/2025.10.06.680703v1

Synchronous spatio-temporal control of autophagy and organelle trafficking is necessary for appressorium-mediated plant infection by Magnaporthe oryzae https://www.biorxiv.org/content/10.1101/2025.10.06.680644v1

LOBSTERS: a modular vector series with a diverse set of Cas nucleases and plasmid selection markers for multiplex genome editing in Saccharomyces cerevisiae https://www.biorxiv.org/content/10.1101/2025.10.05.680590v1

Many circulating indole and phenol metabolites are host derived https://www.biorxiv.org/content/10.1101/2025.10.05.680522v1

Proteomics and Ex Vivo Plaque Culture Identify the Insulin-Like Growth Factor Axis as a Regulator of Carotid Plaque Stability https://www.biorxiv.org/content/10.1101/2025.10.04.680463v1

Catch and release of sialoglycoRNAs enables sequencing-based profiling across cellular and extracellular material https://www.biorxiv.org/content/10.1101/2025.10.04.680438v1

Molecular determinants underlying functional divergence of TBP homologs https://www.biorxiv.org/content/10.1101/2025.10.03.680374v1

Promoter hijacking by primate LINC00473 disrupts an ancestral CREB-PDE10A feedback loop https://www.biorxiv.org/content/10.1101/2025.10.02.680088v1

Structural and mechanistic insights into translation initiation on the enterovirus Type 1 IRES https://www.biorxiv.org/content/10.1101/2025.10.04.680434v1

Lysine-R2HGylation identified as a post-translational modification in R2HG-elevated cancers https://www.biorxiv.org/content/10.1101/2025.10.03.680013v1

Liver angiocrine myeloid-derived growth factor protects against endothelial dysfunction in pulmonary arterial hypertension https://www.biorxiv.org/content/10.1101/2025.10.03.680334v1

Cat_Wiz: A stereochemistry-guided toolkit for locating, diagnosing and annotating Mg2+ ions in RNA structures. https://www.biorxiv.org/content/10.1101/2025.10.04.677962v1

Unveiling the unique interaction mechanism of herpes simplex virus 2 glycoprotein C with C3b https://www.biorxiv.org/content/10.1101/2025.10.04.680448v1

Modeling MEK-inhibitor Associated Retinopathy in vitro using human induced-1 pluripotent stem cell-derived retinal pigment epithelial cells https://www.biorxiv.org/content/10.1101/2025.10.03.680301v1

The interplay between supercoiling and DNA modifying enzymes at the single-molecule level https://www.biorxiv.org/content/10.1101/2025.10.02.680164v1

High Precision Quantification of small RNA Slicing Activity - Native Index Ligation-based Targeted Degradome Sequencing (NIL-TDS) https://www.biorxiv.org/content/10.1101/2025.09.30.679503v1

The G Protein-Coupled Receptor GPR31 Promotes Pro-inflammatory Responses in Pancreatic Islets and Macrophages https://www.biorxiv.org/content/10.1101/2025.10.02.680021v1

Single-cell nanodroplet processing proteomics pipeline for analysis of human-derived microglia https://www.biorxiv.org/content/10.1101/2025.10.02.680067v1