bioRxiv Molecular Biology

Lactucopicrin: A sesquiterpene lactone with anti-inflammatory activity modulates the crosstalk between NF-kB and AHR pathways https://www.biorxiv.org/content/10.1101/2025.08.02.667913v1

Repeat Systemic Delivery of Cross-Neutralization Resistant Synthetic Vesiculoviruses Immunomodulates the Tumor Microenvironment https://www.biorxiv.org/content/10.1101/2025.08.01.668184v1

Immunomodulation of the Innate Host Response by Mesenchymal-Derived Versican during Influenza A Virus Infection https://www.biorxiv.org/content/10.1101/2025.08.01.668194v1

Development of a qPCR assay and tremabiome deep amplicon sequencing method for differentiation of fluke species in livestock https://www.biorxiv.org/content/10.1101/2025.07.31.667929v1

Validated ligand geometries for macromolecular refinement restraints and molecular mechanics force fields https://www.biorxiv.org/content/10.1101/2025.08.01.668229v1

Transcription Represses Origin Activity in a Late-Replicating Fragile Site https://www.biorxiv.org/content/10.1101/2025.08.01.668051v1

Strand Displacement Chain Reaction (SDCR): New Hybrid Amplification Technique for Fast and Sensitive Detection of Genetic Materials https://www.biorxiv.org/content/10.1101/2025.07.31.667828v1

Why budding yeast overrides the DNA damage checkpoint https://www.biorxiv.org/content/10.1101/2025.07.30.667764v1

Brr2p-mediated unwinding of U4/U6 is promoted by a mutually exclusive intra-molecular stem loop in U4 and involves destabilization of the 5' stem-loop of U4 https://www.biorxiv.org/content/10.1101/2025.08.01.667943v1

Purity and stability of modified nucleosides in the context of accurate quantification by LC-MS https://www.biorxiv.org/content/10.1101/2025.07.30.667630v1

A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform https://www.biorxiv.org/content/10.1101/2025.08.01.667725v1

Dynamics of Ribosomal RNA Transcription and Abundance in Normal and Leukemic Hematopoiesis https://www.biorxiv.org/content/10.1101/2025.08.01.668217v1

Mycobiome analysis of electronic cigarettes reveals a reservoir of pathogenic yeasts https://www.biorxiv.org/content/10.1101/2025.08.01.668078v1

Neurotropic and non-neurotropic equid alphaherpesvirus 1 (EHV1) mobilize most histones within viral replication compartments https://www.biorxiv.org/content/10.1101/2025.08.01.668067v1

RNA reinforces condensate nucleation on chromatin to amplify oncogenic transcription https://www.biorxiv.org/content/10.1101/2025.07.29.665963v1

Age-dependent topoisomerase I depletion alters recruitment of rDNA silencing complexes https://www.biorxiv.org/content/10.1101/2025.07.29.667507v1

Pulsed-electron illumination does not reduce beam damage for imaging biological macromolecules https://www.biorxiv.org/content/10.1101/2025.07.29.667395v1

Mechanisms of Cardiomyocyte Aging https://www.biorxiv.org/content/10.1101/2025.07.29.666777v1

A High-Throughput Multiwell-Plate based Approach for the combined Expression, Export and Assay of Recombinant Proteins. https://www.biorxiv.org/content/10.1101/2025.07.29.667353v1

IMPACTS OF DNA METHYLATION ON H2A.Z DEPOSITION AND NUCLEOSOME STABILITY https://www.biorxiv.org/content/10.1101/2025.07.31.667981v1

DNA Circle-sequencing lowers the single molecule sequencing error threshold and identifies ultrasonication as a source of DNA damage https://www.biorxiv.org/content/10.1101/2025.07.30.667586v1

Target-Stabilized Base Editors Enable Robust High-Fidelity RNA Editing https://www.biorxiv.org/content/10.1101/2025.07.31.667791v1

A lncRNA drives developmentally-timed decay of all members of an essential microRNA family https://www.biorxiv.org/content/10.1101/2025.07.30.667716v1

Cannabidiol exerts anti-inflammatory effects but maintains T effector memory cell differentiation: A Single-Cell Study in Humans https://www.biorxiv.org/content/10.1101/2025.07.30.667742v1

Ubiquitin-dependent degradation of p21Waf1/Cip1 is mediated by AMBRA1 to limit DNA replication stress https://www.biorxiv.org/content/10.1101/2025.07.28.666126v1

Organotypic Timelapse recording with Transcriptomic Readout (OTTR) links cell behaviour to cell identity in human tissues https://www.biorxiv.org/content/10.1101/2025.07.28.667119v1

Protein secretion routes in fungi are mostly determined by the length of the hydrophobic helix in the signal peptide https://www.biorxiv.org/content/10.1101/2025.07.30.667231v1

A Trizol-Beadbeater RNA extraction method for yeast, and comparison to Novogene RNA extraction https://www.biorxiv.org/content/10.1101/2025.07.30.667760v1

Split Cas12a protospacer engineering enables ultra-specific, PAM-free detection https://www.biorxiv.org/content/10.1101/2025.07.30.667643v1

Exposure to pyrethroid insecticides modulates immunity of Anopheles against Plasmodium falciparum https://www.biorxiv.org/content/10.1101/2025.07.30.667449v1