๐Here is our editorial on advanced language models like ChaGPT's implications on patients' understanding of complex medical conditions like glomerular diseases. kidney.pub/KN1706-12
#kidneynews @dakidneydoc.bsky.social @asnpublications.bsky.social @kdjhaveri.bsky.social
#chatGPT #glomerulardisease
๐๐ฆ๐ก ๐ฉ๐๐๐๐ข ๐๐๐ฆ๐ง๐ฅ๐๐๐ง ๐ฆ๐๐ฅ๐๐๐ฆ: APOL1 genotype and HIV infection: 20 year outcomes for CKD, CVD and hypertension. 2025 from @kireports.bsky.socialโฌ www.kireports.org/ar...
#VideoAbstract by
โช@drsumanbehera.bsky.socialโฌ & @dakidneydoc.bsky.socialโฌ
๐ญ#WHO created #WorldNoTobaccoDay (WNTD) in '87ย to draw global attention 2 #tobacco epidemic -preventable death & disease caused by it
๐2025 WNTD campaign:โUnmasking the Appeal: Exposing Industry Tactics on Tobacco & Nicotine Productsโ #TobaccoExposed
๐ฉโ๐ซ ๐ฌ bskytorial by @deniiseam.bsky.social
NIH reorganization
No more NIDDK or NHLBI, combined into one institute
www.hhs.gov/sites/defaul...
h/t @jbrianbyrd.bsky.social
#MedSky
Hypoelectrolytemia. Low K, Mg Ca, Na and P.
Did you have to use more than the conservative measures for management?
A glimpse at the causes of an Acquired Bartter Defect too! #ECNeph
@myadla.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social @kajareeg.bsky.social @theisn.org @nephroseeker.medsky.social
๐ In vitro studies suggest that colonic Maxi โ K channels are upregulated
๐ These are the same channels upregulated in CKD, enhancing gut excretion of potassium
๐ In ESRD, the colonic excretion of Potassium is 3-fold that of normal individuals
#ECNeph
@myadla.bsky.social @dramiliflores.bsky.social
Very interesting! I had couple of patients that got diagnosed as Ogilvie syndrome.
25.04.2025 17:20 โ ๐ 1 ๐ 0 ๐ฌ 1 ๐ 0Sounds like pseudoobstruction... seen in patients with Ogilvie syndrome. Can also cause severe electrolyte dysfunction. But quite rare.. mostly diagnosed by GI before the nephrologists get to see them
25.04.2025 17:13 โ ๐ 1 ๐ 1 ๐ฌ 0 ๐ 0
Joining late to this party of electrolyte chaos.
Suman Behera from Toronto.
After sparsentan, another ERA gets accelerated approval on the basis of albuminuria while GFR slope data is being collected
www.novartis.com/us-en/news/m...
@nejm.org paper here www.nejm.org/doi/full/10....
#NephSky
We check renin in all patients refd to the Ottawa hypertension clinic (also 24 hour urine for Na & K)
Renin phenotyping is useful - see data from @anandvaidya17.bsky.social in @ahajournals.bsky.social below
Figure 2
Figure 3
And sema for DM + PAD as well from #ACC25 in @thelancet.bsky.social
www.thelancet.com/journals/lan...
Glipination helps you walk ๐ถ๐ฝ๐ถ๐ปโโ๏ธ๐ถ๐ปโโ๏ธfurther
Happy to be able to share. Looking forward to learning from others as well.
30.03.2025 22:28 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0
Did he have any worsening in kidney function after NET diagnosis? There are several other factors contributing to this as we discussed earlier.. keen to know more.
28.03.2025 17:02 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
Yes. scan had evidence of NET with mets to the liver. none to the kidneys though!
28.03.2025 16:57 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0
#ECNeph #ISNEducation
How hv your experiences & outcomes been in CgA nephropathy (Chromogranin A nephropathy/tubulopathy)? Would be great to hear about your patient outcomes. Add comments
@myadla.bsky.socialโฌ @drpriyajohn.bsky.social @dilushiwijay.bsky.social @theisn.org @arvindcanchi.bsky.social
#ECNeph
What have your experiences been like?
What was your treatment approach?
#ISNEducation #MedEd #Nephrology
@myadla.bsky.socialโฌ @drpriyajohn.bsky.social @dilushiwijay.bsky.social @theisn.org @arvindcanchi.bsky.social
#ECNeph #ISNEducation #CgA Limited documentation/publications
๐ For our patient, treating underlying NET improved kidney function
๐Others have tried PLEX without much success
๐ Usually confused w/chemo or Rx toxicity๐ตโ๐ซ
#Nephrology
@myadla.bsky.socialโฌ @dilushiwijay.bsky.social @theisn.org
Have any of you encounter Chromogranin A (CgA) Nephropathy/Tubulopathy? Not sure how to add a poll on BSKY!๐ค
#ECNeph #ISNEducation
#MedEd #Nephrology
@myadla.bsky.social @drpriyajohn.bsky.social @drmarthagulati.bsky.social @dilushiwijay.bsky.social l @theisn.org @arvindcanchi.bsky.social
#ECNeph #ISNEducation
๐จ When can CgA give false positive results?
โ๏ธ Liver/kidney/heart failure, HTN, inflammatory ds like RA and IBD
#MedEd #Nephrology
@myadla.bsky.socialโฌ @drpriyajohn.bsky.social @dilushiwijay.bsky.social @theisn.org @arvindcanchi.bsky.social
@arvindcanchi.bsky.social thanks to you for creating this space!
28.03.2025 16:46 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0
#ECNeph #ISNEducation
โ๏ธ#CgA = #TumourMarker
๐ฌ CgA positive โก๏ธ several #Neuroendocrine tumours
#MedEd #Nephrology
@myadla.bsky.socialโฌ @drpriyajohn.bsky.social @dilushiwijay.bsky.social @theisn.org @arvindcanchi.bsky.social
๐๏ธWhat is #ChromograninA ?
โ ๏ธHOW DOES IT ACT? โก๏ธ cytokines, degranulation, apoptosis... Lots of inflammatory processesโก๏ธ
#ECNeph #ISNEducation
#MedEd #Nephrology
@myadla.bsky.socialโฌ @drpriyajohn.bsky.social @dilushiwijay.bsky.social @theisn.org @arvindcanchi.bsky.social
#ECNeph #ISNEducation
โก๏ธ๐ฌ What else can cause Eosinophilic Intracytoplsmic Tubular inclusions/granules:
๐ชRhabdomyolysis, ๐ฆนmalignancies, ๐ฎโ๐จchronic inflammation
๐พPaneth cell like granules - ccRCC
๐ธ HES
@myadla.bsky.socialโฌ @drpriyajohn.bsky.social @theisn.org @arvindcanchi.bsky.social
#ECNeph #ISNEducation
๐ฌ Eosinophilic Intracytoplasmic tubular inclusions/granules are also seen in: Light chain proximal tubulopathy, MM, Drug induced Fanconi synd.
#MedEd #Nephrology
@myadla.bsky.socialโฌ @drpriyajohn.bsky.social @dilushiwijay.bsky.social @theisn.org @arvindcanchi.bsky.social
#ECNeph #CgATubulopathy #CgANephropathy โก๏ธ Acute Tubular Injury.
๐๏ธ#chromograninA expands/swells and collects within #ProximalTubules
๐๏ธ #CgA forms intraluminal #tubular #casts
@myadla.bsky.socialโฌ @drpriyajohn.bsky.social @dilushiwijay.bsky.social @theisn.org @arvindcanchi.bsky.social
pubmed.ncbi.nlm.nih.gov/36100605/
The FLC ratio is normal for that level of kidney function.. also has a h/o MGUS. #ECNeph
