Rob Horne's Avatar

Rob Horne

@robertihorne.bsky.social

Drug discovery fellow @ D. E. Shaw Research focusing on cancer treatments 🧫 PhD from Uni of Cambridge working on inhibitors of neurodegenerative disease 🧠

901 Followers  |  1,354 Following  |  16 Posts  |  Joined: 29.11.2024
Posts Following

Posts by Rob Horne (@robertihorne.bsky.social)

Design of Tau Aggregation Inhibitors Using Iterative Machine Learning and a Polymorph-Specific Brain-Seeded Fibril Amplification Assay #Drosophila PubMed link

Design of Tau Aggregation Inhibitors Using Iterative Machine Learning and a Polymorph-Specific Brain-Seeded Fibril Amplification Assay
#Drosophila

18.09.2025 17:23 — 👍 2    🔁 1    💬 0    📌 0
Design of Tau Aggregation Inhibitors Using Iterative Machine Learning and a Polymorph-Specific Brain-Seeded Fibril Amplification Assay

Design of Tau Aggregation Inhibitors Using Iterative Machine Learning and a Polymorph-Specific Brain-Seeded Fibril Amplification Assay

Figure 1

Figure 1

Figure 2

Figure 2

Figure 3

Figure 3

Design of Tau Aggregation Inhibitors Using Iterative Machine Learning and a Polymorph-Specific Brain-Seeded Fibril Amplification Assay [new]

14.03.2025 22:02 — 👍 1    🔁 1    💬 0    📌 0
Preview
Sequence-based virtual screening using transformers - Nature Communications Ligand-Transformer is a deep learning framework that predicts protein–ligand binding and conformational changes using only sequence and 2D-structure inputs, enabling efficient virtual screening and un...

Happy to have been able to contribute to this! @natcomms.nature.com

www.nature.com/articles/s41...

29.07.2025 02:52 — 👍 0    🔁 0    💬 0    📌 0
Preview
Design of immunogens to present a tumor-specific cryptic epitope - Scientific Reports Scientific Reports - Design of immunogens to present a tumor-specific cryptic epitope

New paper from @deshawresearch.com #cancer #vaccines

www.nature.com/articles/s41...

03.04.2025 01:21 — 👍 2    🔁 0    💬 0    📌 0
Preview
Detection of protein oligomers with nanopores  - Nature Reviews Chemistry An overview of the progress and potential of nanopore-based detection of oligomerizing proteins is presented, covering the latest advances and combination with other emerging technologies including de...

Would you like to learn about a cutting edge diagnostic/characterisation technique for #neurodegenerative disease? Check out our review here! @sarahesandler.bsky.social @natrevchem.bsky.social
@wyssinstitute.bsky.social
@chemlibcam.bsky.social
#nanopore

Full text: rdcu.be/ech4q

05.03.2025 16:50 — 👍 5    🔁 4    💬 0    📌 0
Preview
Meditations on mentorship and legacy Nature Reviews Chemistry, Published online: 13 March 2025; doi:10.1038/s41570-025-00708-4Mary Garson is an Emerita Professor of the University of Queensland and President-elect of the International Union of Pure and Applied Chemistry (IUPAC). In 2024, The…
14.03.2025 03:24 — 👍 6    🔁 3    💬 0    📌 0
Post image

We welcome summer intern applications from undergrad and grad students for our CS, ML, and biochemistry efforts to work on projects such as developing ML models for drug discovery, ML kernels/infrastructure, and large-scale data management/analysis code. apply.deshawresearch.com/careers/Regi...

12.03.2025 13:44 — 👍 5    🔁 1    💬 0    📌 0
Preview
Detection of protein oligomers with nanopores  - Nature Reviews Chemistry An overview of the progress and potential of nanopore-based detection of oligomerizing proteins is presented, covering the latest advances and combination with other emerging technologies including de...

Detection of protein oligomers with nanopores

nature.com/articles/s41...

A new Review from @robertihorne.bsky.social @sarahesandler.bsky.social Michele Vendruscolo & Ulrich F. Keyser

06.03.2025 13:56 — 👍 5    🔁 3    💬 0    📌 0
Preview
Detection of protein oligomers with nanopores  Nature Reviews Chemistry, Published online: 05 March 2025; doi:10.1038/s41570-025-00694-7An overview of the progress and potential of nanopore-based detection of oligomerizing proteins is presented, covering the latest advances and combination with other…
05.03.2025 21:49 — 👍 6    🔁 2    💬 0    📌 0
Preview
Detection of protein oligomers with nanopores  - Nature Reviews Chemistry An overview of the progress and potential of nanopore-based detection of oligomerizing proteins is presented, covering the latest advances and combination with other emerging technologies including de...

Would you like to learn about a cutting edge diagnostic/characterisation technique for #neurodegenerative disease? Check out our review here! @sarahesandler.bsky.social @natrevchem.bsky.social
@wyssinstitute.bsky.social
@chemlibcam.bsky.social
#nanopore

Full text: rdcu.be/ech4q

05.03.2025 16:50 — 👍 5    🔁 4    💬 0    📌 0

Hey could I be added to ML for drug discovery? Thanks!

06.12.2024 01:39 — 👍 1    🔁 0    💬 1    📌 0

Hey could I be added please!

30.11.2024 22:11 — 👍 0    🔁 0    💬 0    📌 0

Hey could I be added?

30.11.2024 21:55 — 👍 0    🔁 0    💬 1    📌 0

Hi could I be added please!

30.11.2024 21:48 — 👍 1    🔁 0    💬 1    📌 0

Could I be added please!

30.11.2024 21:32 — 👍 1    🔁 0    💬 1    📌 0

Could I be added to this please? Thanks!

30.11.2024 21:27 — 👍 1    🔁 0    💬 0    📌 0

Could I join please?

30.11.2024 21:23 — 👍 1    🔁 0    💬 1    📌 0

Could I join please?

30.11.2024 21:09 — 👍 0    🔁 0    💬 1    📌 0

Hi could I be added to this please?

30.11.2024 20:08 — 👍 1    🔁 0    💬 1    📌 0

Could you add me please?

30.11.2024 17:52 — 👍 0    🔁 0    💬 1    📌 0

@srijitseal.com hey could you add me to the cheminformatics starter you set up?

30.11.2024 17:52 — 👍 0    🔁 0    💬 1    📌 0

@pkpd-babe.bsky.social
Could I be added to Scientists + Clinicians in Neurodegeneration please?

30.11.2024 17:46 — 👍 0    🔁 0    💬 0    📌 0

Could I be added to this please?

29.11.2024 18:31 — 👍 1    🔁 0    💬 0    📌 0