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Prof David Wraith

@cameron-wraith.bsky.social

Erstwhile immunologist still working on designing antigen-specific immunotherapies for autoimmune diseases

1,419 Followers  |  280 Following  |  22 Posts  |  Joined: 20.10.2024  |  1.9248

Latest posts by cameron-wraith.bsky.social on Bluesky

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Suggest you jump in on this poll.

β€”> xd.wayin.com/display/cont...?

And share…

21.10.2025 07:34 β€” πŸ‘ 964    πŸ” 835    πŸ’¬ 329    πŸ“Œ 87
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From Valley of the temples: Agrigento. A wonderful setting for a perfect statement.

25.09.2025 10:36 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Trump & Epstein on Windsor castle #fyp TikTok video by Led By Donkeys

Full length video here, 9:01 minutes long - amazing work @ledbydonkeys.org.

17.09.2025 08:25 β€” πŸ‘ 49    πŸ” 32    πŸ’¬ 2    πŸ“Œ 5
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Meet the non-doms fighting Rachel Reeves’s tax raid With chancellor planning tax shake-up in this month’s Budget, Foreign Investors for Britain is trying to affect debate

It's a tax "raid". When you or I pay our income tax it's just a tax. But when a fabulously wealthy millionaire who refuses to contribute to the country whose public services they use (and yes, they use roads, defence, police etc) it's a "raid".
www.ft.com/content/8882...

14.08.2025 08:34 β€” πŸ‘ 369    πŸ” 137    πŸ’¬ 12    πŸ“Œ 6

In 2023, I was told by a police officer in Kharkiv that if Ukraine loses the war, β€œall of Europe will burn.”

We need to understand this. Parts of Europe understand it but too many people in the UK still think the war is β€œover there”. It’s not us and them. Ukraine is us.

12.08.2025 18:11 β€” πŸ‘ 82    πŸ” 24    πŸ’¬ 1    πŸ“Œ 0

This buffoon blames Zelensky for starting the war that Russia waged on his nation...........what the hell hope is there for Ukraine with Trump involved? Europe must stand firm with Ukraine and stop this madness......

11.08.2025 17:30 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 2    πŸ“Œ 0

This is batshit crazy. UK and EU must go all out to invest in this proven technology. Millions of RNA vaccine doses have been given with minimal side effects.

06.08.2025 07:24 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Immune reset plus: this figure illustrates the advantage of combining Immune Reset by B cell depletion with antigen-specific immunotherapy. ASIT with antigens delivered to tolerogenic APC can β€˜switch off’ autoreactive T cells while promoting differentiation of antigen-specific regulatory T cell populations. Most importantly, ASIT approaches have been shown to function in B cell depleted animal models. Tolerance induction by ASIT depends on antigen presentation by steady state dendritic cells in lymphoid organs or by APC in the tolerogenic environment of the liver. Immune reset plus ASIT will enable disease to be controlled without continued B cell depletion. This will allow the treated individual to control infections and respond to vaccines.

Immune reset plus: this figure illustrates the advantage of combining Immune Reset by B cell depletion with antigen-specific immunotherapy. ASIT with antigens delivered to tolerogenic APC can β€˜switch off’ autoreactive T cells while promoting differentiation of antigen-specific regulatory T cell populations. Most importantly, ASIT approaches have been shown to function in B cell depleted animal models. Tolerance induction by ASIT depends on antigen presentation by steady state dendritic cells in lymphoid organs or by APC in the tolerogenic environment of the liver. Immune reset plus ASIT will enable disease to be controlled without continued B cell depletion. This will allow the treated individual to control infections and respond to vaccines.

Good to see our article proposing a new approach to the effective control of autoimmune diseases beyond Immune Reset. β€˜Immune reset plus’: the case for combining immunotherapies to maintain self-tolerance in autoimmune diseases in Frontiers in Immunology: www.frontiersin.org/journals/imm...

23.07.2025 12:05 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Great opportunity to work with the leader in the field of fungal immunology and wonderful colleagues in Birmingham.....

23.06.2025 14:33 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Anyone else spot that this wonderful trade deal has no TEXT only a signature. How does the phrase 'Not worth the paper it's written on' work in this case............

17.06.2025 10:56 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Good to hear UK PM Keir Starmer promote the ELSA screening programme for type 1 diabetes being run from the University of Birmingham by Parth Narendran and his team. See this on BBC iPlayer PMQs 12.28 to 12.30.

11.06.2025 12:28 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Anyone who has benefitted from the outstanding NHS knows that we live on a rich, multicultural society wth the very best of people; these are not strangers they're heroes.

17.05.2025 16:41 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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So, that new give Putin all he wants "peace" plan Rubio floated this week? It appears to be illegal under a 2022 American law Rubio himself helped pass.

www.politico.com/newsletters/...

24.04.2025 11:42 β€” πŸ‘ 3735    πŸ” 1423    πŸ’¬ 126    πŸ“Œ 79
The Editorial in full.

The Editorial in full.

πŸ†• β€œScience and medicine in the USA are being violently dismembered while the world watches [...] bullies are only emboldened by acquiescence or indifference.”

The Lancet’s latest Editorial: Supporting medical science in the USA www.thelancet.com/journals/lan...

25.04.2025 12:28 β€” πŸ‘ 202    πŸ” 114    πŸ’¬ 4    πŸ“Œ 6
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UK academic tracks Trump’s agenda β€˜to discredit science’ - Research Professional News β€œThis isn’t chaosβ€”it’s a deliberate war on science and academic freedom,” says Christina Pagel

UK academic tracks Trump’s agenda β€˜to discredit science’.

β€œThis isn’t chaosβ€”it’s a deliberate war on science and academic freedom,” says Christina Pagel (@chrischirp.bsky.social).

www.researchprofessionalnews.com/rr-news-worl...

23.04.2025 15:46 β€” πŸ‘ 43    πŸ” 17    πŸ’¬ 0    πŸ“Œ 0

Good to see Stanford standing with Harvard..........we need to hear from the student community as well as college heads.

16.04.2025 13:56 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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πŸŽ₯Β We’re excited to share our new video! (part of Innovate UK ICURe) It… | Sky Ng πŸŽ₯Β We’re excited to share our new video! (part of Innovate UK ICURe) It highlights how our platform is accelerating the development of autoimmune therapiesβ€”making it faster and more precise to go from ...

iCURE
Happy to support Sky in the lab who is promoting recent work from the lab through the Innovate UK iCURE programme.
www.linkedin.com/feed/update/...

16.04.2025 12:24 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

The irony is bliss...... After all, the last "...'ll fix it" ended so well!

31.03.2025 13:32 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Effective cancer vaccines combined with checkpoint inhibitors has to be the way to prevent cancer while reducing the risk of autoimmunity. To limit research on this is criminal.

29.03.2025 09:52 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0

Happy Birthday, good to see he has your sense of humour!!

22.03.2025 11:14 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

This NIH ruling is dangerous. EU and UK funding agencies must call for proposals for RNA vaccine research to attract the best scientists to apply, including our colleagues in the U.S. whose work is no longer safe in their home country.

17.03.2025 11:32 β€” πŸ‘ 16    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

And wears a suit and tie when he does so.......

11.03.2025 17:00 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Map of Stand Up for Science events, with official SUFS events in Red and solidarity events in Blue

Map of Stand Up for Science events, with official SUFS events in Red and solidarity events in Blue

WHERE WILL YOU BE ON MARCH 7TH!?

Head to www.standupforscience2025.org/local-event-information/ or the link in our bio to find your closest eventβ€”or add one if you're hosting one!

#standupforscience2025

02.03.2025 02:04 β€” πŸ‘ 2271    πŸ” 1168    πŸ’¬ 77    πŸ“Œ 176

This is spot on from the former foreign minister of Lithuania, Ukraine has to be sovereign............

03.03.2025 11:51 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

We must all support and applaude PLOS for adhering to their core principles.

22.02.2025 08:44 β€” πŸ‘ 39    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0

Hmm, wonder if such a thing could pay for our increased defense bill, that would be such a novel idea!?!

27.02.2025 23:24 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

This is potentially devastating. Surely, this meeting should be reconvened at the World Influenza Centre in London, urgently.

27.02.2025 23:19 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

So who is the aggressor Mr Trump, Putin is laughing at the US..........

23.02.2025 13:45 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Montana lawmakers reject proposed ban on mRNA vaccines β€’ Daily Montanan Bill would have criminalized the administration of mRNA-based vaccines such as the COVID-19 shot

Some actual good news, for now, Montana lawmakers overwhelmingly rejected the proposed ban on mRNA vaccines. 🩺 πŸ›Ÿ

21.02.2025 17:59 β€” πŸ‘ 193    πŸ” 42    πŸ’¬ 5    πŸ“Œ 3

We must all support and applaude PLOS for adhering to their core principles.

22.02.2025 08:44 β€” πŸ‘ 39    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0

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