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BaladoCritique : club de lecture médical

@baladocritique.bsky.social

Baladodiffusion qui analyse les études de médecine interne/médecine familiale depuis 2016. Éditeurs : Dr L. Lanthier, Dr M. Cauchon, Dr A. Mutchmore. En collaboration avec l'Université de Sherbrooke (Québec). https://www.usherbrooke.ca/baladocritique

96 Followers  |  104 Following  |  570 Posts  |  Joined: 22.01.2025
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Posts by BaladoCritique : club de lecture médical (@baladocritique.bsky.social)

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Le prochain balado de BaladoCritique : club de lecture médical, portera sur l'essai clinique ADJUST-DVT, publié dans le
@jama.com en février, sur les D-Dimères ajustés pour l'âge dans la thrombose veineuse profonde.
À suivre !
#MedSky

02.03.2026 23:55 — 👍 0    🔁 0    💬 0    📌 0
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The 🆕 ACC/AHA Guideline for the Evaluation & Management of Acute Pulmonary Embolism (PE) in Adults is a de novo document offering comprehensive, evidence‑based recommendations for the evaluation, management & follow‑up of adults w/ acute PE.

Read more: https://bit.ly/4aE5gmi #ClinicalGuidelines

19.02.2026 19:16 — 👍 3    🔁 3    💬 0    📌 0
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Tecovirimat for the Treatment of Mpox | NEJM Tecovirimat is approved for smallpox treatment under the Food and Drug Administration Animal Rule on the basis of efficacy in nonhuman primate models of mpox (previously known as monkeypox). Howeve...

“Tecovirimat for the Treatment of Mpox.”
Publié ce jour dans le @nejm.org.
#MedSky #IDSky
www.nejm.org/doi/full/10....

26.02.2026 12:13 — 👍 0    🔁 0    💬 0    📌 0
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Cabotegravir plus Rilpivirine for Persons with HIV and Adherence Challenges | NEJM Randomized trials of long-acting injectable antiretroviral therapy (ART) in persons with human immunodeficiency virus (HIV) who face challenges with adherence to oral medication are lacking. We con...

“Cabotegravir plus Rilpivirine for Persons with HIV and Adherence Challenges.”
Publié ce jour dans le @nejm.org.
#MedSky #IDSky
www.nejm.org/doi/full/10....

26.02.2026 12:08 — 👍 0    🔁 0    💬 0    📌 0
A flowchart titled 'Management of Restless Legs Syndrome'. It outlines steps from initial diagnosis to treatment based on serum ferritin/TSAT levels and symptom frequency, including iron, gabapentinoids, or other combined therapies if needed.

A flowchart titled 'Management of Restless Legs Syndrome'. It outlines steps from initial diagnosis to treatment based on serum ferritin/TSAT levels and symptom frequency, including iron, gabapentinoids, or other combined therapies if needed.

Restless legs syndrome (RLS), a sleep-related movement disorder, is present in approximately 3% of adults worldwide.

📄 This Review summarizes the pathophysiology, epidemiology, risk factors, diagnosis, treatment, and prognosis of #RestlessLegsSyndrome.

ja.ma/4rB7EBD

24.02.2026 16:15 — 👍 9    🔁 4    💬 0    📌 1
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2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical... AIM The “2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease” provides recommendations to guide clinicians on the evaluation and treatment of adult patien...

"2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines."
Publié ce jour dans Circulation.
#MedSky
www.ahajournals.org/doi/full/10....

24.02.2026 17:47 — 👍 0    🔁 0    💬 0    📌 0
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New! 🎙️🩺🎧 #515 Primary Aldosteronism, A Deep Dive: Easy on the Salt! 🧂⬇️

Hypertension is everywhere and primary aldosteronism is a common (and often missed 👀) cause. Join us with @anandvaidya17.bsky.social of Brigham and Women’s Hospital

23.02.2026 12:49 — 👍 6    🔁 2    💬 0    📌 1
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Cost-effectiveness of sodium–glucose cotransporter 2 inhibitors and glucagon-like peptide-1 receptor agonists for patients with high cardiovascular risk and type 2 diabetes in Canada Background: Diabetes Canada and the Canadian Cardiovascular Society recommend that patients with type 2 diabetes and cardiovascular disease, renal disease, or multiple cardiovascular risk factors begi...

"Cost-effectiveness of sodium–glucose cotransporter 2 inhibitors and glucagon-like peptide-1 receptor agonists for patients with high cardiovascular risk and type 2 diabetes in Canada."
Publié ce jour dans @cmaj.ca
#MedSky #EndoSky
www.cmaj.ca/content/198/...

23.02.2026 13:19 — 👍 1    🔁 0    💬 0    📌 0
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Menopausal hormone therapy and long term mortality: nationwide, register based cohort study Objective To assess whether menopausal hormone therapy increases the risk of all cause mortality. Design Nationwide, registry based cohort study. Setting Denmark. Participants Danish women born bet...

"Menopausal hormone therapy and long term mortality: nationwide, register based cohort study."
Publié ce jour dans @bmj.com.
#MedSky
www.bmj.com/content/392/...

21.02.2026 14:16 — 👍 1    🔁 0    💬 0    📌 0
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Effectiveness of drug interventions to prevent delirium after surgery for older adults: systematic review and network meta-analysis of randomised controlled trials Objective To identify which drugs are effective at preventing delirium after surgery in adults over 60 years of age and estimate the effects on morbidity and mortality. Design Systematic review and n...

"Effectiveness of drug interventions to prevent delirium after surgery for older adults: systematic review and network meta-analysis of randomised controlled trials."
Publié ce jour dans @bmj.com.
#MedSky
www.bmj.com/content/392/...

21.02.2026 13:47 — 👍 0    🔁 0    💬 0    📌 0
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Tenecteplase versus standard medical treatment for basilar artery occlusion within 24 h (TRACE-5): a multicentre, prospective, randomised, open-label, blinded-endpoint, superiority, phase 3 trial In this trial involving Chinese patients with ischaemic stroke due to basilar artery occlusion, tenecteplase within 24 h after stroke onset improved functional outcome compared with standard medical t...

“Tenecteplase versus standard medical treatment for basilar artery occlusion within 24 h (TRACE-5): a multicentre, prospective, randomised, open-label, blinded-endpoint, superiority, phase 3 trial.”
Publié ce jour dans @thelancet.com.
#MedSky #NeuroSky
www.thelancet.com/journals/lan...

21.02.2026 13:36 — 👍 0    🔁 0    💬 0    📌 0
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Effectiveness and Safety of Statins in Type 2 Diabetes According to Baseline Cardiovascular Risk: A Target Trial Emulation Study: Annals of Internal Medicine: Vol 179, No 2 Background: Whether statins benefit patients with type 2 diabetes mellitus (T2DM) with low predicted 10-year cardiovascular risk is uncertain. Objective: To evaluate the effectiveness and safety of st...

"Effectiveness and Safety of Statins in Type 2 Diabetes According to Baseline Cardiovascular Risk: A Target Trial Emulation Study."
Publié en février dans @annalsofim.bsky.social.
#MedSky #EndoSky
www.acpjournals.org/doi/10.7326/...

20.02.2026 20:10 — 👍 0    🔁 0    💬 0    📌 0
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Teclistamab plus Daratumumab in Relapsed or Refractory Multiple Myeloma | NEJM In a phase 1–2 trial, teclistamab, a bispecific antibody targeting CD3 on T-cell surfaces and B-cell maturation antigen on myeloma cells, showed durable responses in heavily pretreated patients wit...

"Teclistamab plus Daratumumab in Relapsed or Refractory Multiple Myeloma."
Publié ce jour dans le @nejm.org
#MedSky www.nejm.org/doi/full/10....

19.02.2026 14:15 — 👍 0    🔁 0    💬 0    📌 0
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Transcatheter or Surgical Aortic-Valve Replacement in Low-Risk Patients at 7 Years | NEJM Five-year data from the PARTNER 3 trial showed that among low-risk patients with severe, symptomatic aortic stenosis, outcomes were similar among patients who had undergone transcatheter aortic-val...

« Transcatheter or Surgical Aortic-Valve Replacement in Low-Risk Patients at 7 Years. »
Publié ce jour dans le @nejm.org.
#MedSky #CardioSky
www.nejm.org/doi/full/10....

19.02.2026 12:17 — 👍 0    🔁 0    💬 0    📌 0
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European Society for Vascular Surgery (ESVS) 2026 Clinical Practice Guidelines on the Management of Descending Thoracic and Thoraco-Abdominal Aortic Diseases – Editor's Choice The European Society for Vascular Surgery (ESVS) has developed clinical practice guidelines for the care of patients with descending thoracic and thoraco-abdominal aortic pathologies, in succession to...

"European Society for Vascular Surgery (ESVS) 2026 Clinical Practice Guidelines on the Management of Descending Thoracic and Thoraco-Abdominal Aortic Diseases."
Publié en février dans European Journal of Vascular and Endovascular Surgery.
#MedSky
www.ejves.com/article/S107...

18.02.2026 15:59 — 👍 0    🔁 0    💬 0    📌 0
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Acute Coronary Syndromes in Premenopausal Women: A Scientific Statement From the American Heart Association | Circulation Premenopausal women presenting with acute coronary syndrome (ACS) are a unique and often underrecognized patient population. Although they are traditionally considered at lower cardiovascular risk tha...

"Acute Coronary Syndromes in Premenopausal Women: A Scientific Statement From the American Heart Association."
Publié ce jour dans Circulation.
#MedSky #CardioSky @ahajournals.bsky.social www.ahajournals.org/doi/full/10....

17.02.2026 13:32 — 👍 1    🔁 0    💬 0    📌 0
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Transthyretin Cardiac Amyloidosis Evaluation and Management: 2025 ACC Concise Clinical Guidance:

"Transthyretin Cardiac Amyloidosis Evaluation and Management: 2025 ACC Concise Clinical Guidance."
Publié en février dans JACC.
#MedSky #CardioSky
www.jacc.org/doi/10.1016/...

16.02.2026 19:13 — 👍 1    🔁 0    💬 0    📌 0
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EASL Clinical Practice Guidelines on vascular diseases of the liver Vascular diseases of the liver include portal vein thrombosis (with or without cirrhosis), portosinusoidal vascular disorder, Budd-Chiari syndrome, sinusoidal obstruction syndrome, non-obstructive sin...

"EASL Clinical Practice Guidelines on vascular diseases of the liver."
Publié en février dans Journal of Hepatology.
#MedSky #LiverSky
www.journal-of-hepatology.eu/article/S016...

16.02.2026 19:09 — 👍 0    🔁 0    💬 0    📌 0
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AGA Clinical Practice Update on Evaluation and Management of Refractory Constipation: Expert Review Although most patients with chronic constipation respond to medical therapy, a subset experiences refractory constipation (RC), which poses unique diagnostic and therapeutic challenges. Because RC is ...

"AGA Clinical Practice Update on Evaluation and Management of Refractory Constipation: Expert Review."
Publié en février dans Clinical Gastroenterology and Hepatology.
#MedSky #GastroSky www.cghjournal.org/article/S154...

16.02.2026 18:48 — 👍 0    🔁 0    💬 0    📌 0
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🔥Just published 🔥
ESCMID Clinical Guidelines on the Evaluation and Management of a Reported Antibiotic Allergy #IDSjy
www.clinicalmicrobiologyandinfection.org/article/S119...

16.02.2026 14:12 — 👍 28    🔁 12    💬 2    📌 3
Line graph titled 'Incident dementia' shows hazard ratio (95% CI) vs. caffeinated coffee intake (c/d). The curve slopes down initially, then flattens. P<.001 for nonlinearity. Intake, c/d values range from 0 to >5, with case numbers and person-years listed.

Line graph titled 'Incident dementia' shows hazard ratio (95% CI) vs. caffeinated coffee intake (c/d). The curve slopes down initially, then flattens. P<.001 for nonlinearity. Intake, c/d values range from 0 to >5, with case numbers and person-years listed.

From @jama.com: Moderate consumption of caffeinated coffee or tea was linked to reduced #dementia risk and modest improvements in cognitive outcomes; no benefit was seen for decaffeinated coffee in an observational study of US adults.

ja.ma/4kLg9az

14.02.2026 14:00 — 👍 1    🔁 1    💬 0    📌 0
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Assessment of adverse effects attributed to statin therapy in product labels: a meta-analysis of double-blind randomised controlled trials Adverse event data from blinded randomised trials do not support causal relationships between statin therapy and most of the conditions (including cognitive impairment, depression, sleep disturbance, ...

“Assessment of adverse effects attributed to statin therapy in product labels: a meta-analysis of double-blind randomised controlled trials.”
Publié ce jour dans @thelancet.com.
#MedSky #EndoSky
www.thelancet.com/journals/lan...

14.02.2026 13:26 — 👍 0    🔁 0    💬 0    📌 0
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Efficacy and safety of minocycline in patients with acute ischaemic stroke (EMPHASIS): a multicentre, double-blind, randomised controlled trial Minocycline therapy initiated within 72 h of acute ischaemic stroke provided a significant functional outcome benefit compared with placebo at 90 days, without safety concerns. Future studies are need...

“Efficacy and safety of minocycline in patients with acute ischaemic stroke (EMPHASIS): a multicentre, double-blind, randomised controlled trial.”
Publié ce jour dans @thelancet.com.
#MedSky #NeuroSky
www.thelancet.com/journals/lan...

14.02.2026 13:04 — 👍 0    🔁 0    💬 0    📌 0
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Therapy for Atrial Fibrillation in Patients with Drug-Eluting Stents | NEJM Despite guideline recommendations, evidence for the use of non–vitamin K antagonist oral anticoagulant (NOAC) monotherapy in patients with atrial fibrillation after implantation of a drug-eluting s...

“Therapy for Atrial Fibrillation in Patients with Drug-Eluting Stents.”
Publié ce jour dans le @nejm.org.
#MeeSky #CardioSky
www.nejm.org/doi/full/10....

12.02.2026 12:06 — 👍 0    🔁 0    💬 0    📌 0
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State-of-the-Art Review: Diagnosis and Management of Acute and Chronic Bacterial Prostatitis Abstract. Acute bacterial prostatitis (ABP) and chronic bacterial prostatitis (CBP) are poorly defined clinical entities, and diagnosis can be challenging.

"State-of-the-Art Review: Diagnosis and Management of Acute and Chronic Bacterial Prostatitis."
Publié en janvier dans Clin Infect Dis.
#MedSky academic.oup.com/cid/article/...

10.02.2026 13:34 — 👍 0    🔁 0    💬 0    📌 0
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Fasciite à éosinophiles.
Par #InternistAcademy
@terrierben.bsky.social
#MedSky

08.02.2026 15:50 — 👍 0    🔁 0    💬 0    📌 0
Figure showing localised and locally advanced non-metastatic prostate cancer: different treatment options per risk group. Copyright: 2025 Elsevier Ltd. All rights are reserved.

Figure showing localised and locally advanced non-metastatic prostate cancer: different treatment options per risk group. Copyright: 2025 Elsevier Ltd. All rights are reserved.

The therapeutic landscape for prostate cancer has evolved substantially in the past 5 years, resulting in improved patient outcomes.

A Seminar provides an up-to-date overview of the management of prostate cancer at different stages of the disease: spkl.io/63322AsbtC

07.02.2026 13:00 — 👍 5    🔁 4    💬 0    📌 0
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Trastuzumab Deruxtecan plus Pertuzumab for HER2-Positive Metastatic Breast Cancer | NEJM Trastuzumab deruxtecan has shown efficacy in patients with previously treated human epidermal growth factor receptor 2 (HER2)–positive advanced or metastatic breast cancer. The efficacy and safety ...

"Trastuzumab Deruxtecan plus Pertuzumab for HER2-Positive Metastatic Breast Cancer."
Publié ce jour dans le @nejm.org.
#MedSky
www.nejm.org/doi/full/10....

05.02.2026 13:25 — 👍 0    🔁 0    💬 0    📌 0
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Beta-Blockers after Myocardial Infarction with Normal Ejection Fraction | NEJM The benefit of beta-blockers after myocardial infarction in patients with a preserved left ventricular ejection fraction (LVEF) is unclear. We conducted a meta-analysis at the individual-patient le...

“Beta-Blockers after Myocardial Infarction with Normal Ejection Fraction.”
Publié ce jour dans le @nejm.org.
#MedSky #CardioSky
www.nejm.org/doi/full/10....

05.02.2026 12:10 — 👍 1    🔁 1    💬 0    📌 0
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A Placebo-Controlled Trial of the Oral PCSK9 Inhibitor Enlicitide | NEJM Enlicitide decanoate, an oral proprotein convertase subtilisin–kexin type 9 (PCSK9) inhibitor, was shown to reduce low-density lipoprotein (LDL) cholesterol levels in a phase 2 trial; longer-term d...

“A Placebo-Controlled Trial of the Oral PCSK9 Inhibitor Enlicitide.”
Publié ce jour dans le @nejm.org.
#MedSky #EndoSky
www.nejm.org/doi/full/10....

05.02.2026 12:05 — 👍 0    🔁 0    💬 0    📌 0