Da-Neng Wang

🌟 WeINSPIREBio is hosting its first event!

On Dec 4, we’re running a webinar:

Structures of Success: Career Journeys of Women in Structural Biology

If you work in SB, drug discovery, or just like hearing career stories from brilliant people, join us! And please share 🙏🏼

lnkd.in/ewjD5WPt

#cryoEM

I needed this…

Oh, Canada. What are you doing to us?

Excited to share our latest @nature.com: How does naloxone (Narcan) stop an opioid overdose? We determined the first GDP-bound μ-opioid receptor–G protein structures and found naloxone traps a novel "latent” state, preventing GDP release and G protein activation.💊🧪 🧵👇 www.nature.com/articles/s41...

Go New Jersey!!!

We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. 🤗 RTs appreciated.

mrc.tal.net/vx/appcentre...

New online: New York City’s structural biology mosaic

Assistant/associate Professor of AI-assisted Biophysics at the Ecole polytechnique fédérale de Lausanne (EPFL) and Group Leader at the Paul Scherrer Institute (PSI) The School of Basic Sciences (Physics, Chemistry and Mathematics) at EPFL and the Paul Scherrer Institute (PSI) jointly seek to appoint a Tenure Track Assistant or tenured Associate Professor in AI-As...

#EPFL has an open faculty position - tenure track or tenured!! - in AI driven biophysics. Deadline is Nov 15th. Please spread the word!

www.epfl.ch/about/workin...

Fred Hutch's Human Biology Division is recruiting an Assistant or Associate Professor to lead a laboratory-based research program focused on the biological mechanisms of solid tumor cancers and their clinical translation. Learn more and apply: https://apply.interfolio.com/174007

Chris Russo and Anastasiia Gusach have developed a new method to prepare #cryoEM samples that avoids protein damage during freezing

Read more: www2.mrc-lmb.cam.ac.uk/a-new-method...

#LMBResearch

Assistant Professor in Structural Biology and Biochemistry, Department of Molecular Biology & Biochemistry University of California, Irvine is hiring. Apply now!

Our home department of Molecular Biology & Biochemistry at UC Irvine is looking to hire a new tenure-track assistant professor in the broad area of structural biology. Come be our colleague! recruit.ap.uci.edu/JPF09887

Please apply and/or share this post.

UGA is seeking a tenure-track Assistant Professor to develop an innovative research program focused on disease mechanisms. The ideal candidate will use cryo-EM and other structural techniques, with potential applications to future therapies.
Apply here: www.ugajobsearch.com/postings/456...

The Department of Biochemistry and Molecular Biology at UTHealth Houston has an open search for a tenure-track faculty position. If you are ready (or know someone that is) to start looking for positions, this will be a great opportunity to join the Texas Medical Center. See flyer below. 1/2

Endogenous structure of antimalarial target PfATP4 reveals an apicomplexan-specific P-type ATPase modulator Nature Communications - Here, the authors present the 3.7 Å cryoEM structure of native sodium efflux pump PfATP4 from Plasmodium falciparum, revealing a bound protein that they term...

Learn how our hunt for the native structure of top antimalarial target PfATP4🧂led to the discovery of PfABP, an unknown essential binding partner, out now! @natcomms.nature.com 👉 rdcu.be/eLRlH 🦠🔬❄️

A team effort led by @mehsehret.bsky.social & Anurag Shukla @akhilvaidya.bsky.social! #cryoEM #malaria

Collaborative. Creative. Impactful. Come join us in Ann Arbor! For more information and application link see jobs.sciencecareers.org/job/675674/f...

Hijacking a bacterial ABC transporter for genetic code expansion - Nature Bacterial ATP-binding cassette (ABC) transporters can be utilized and engineered to transport non-canonical amino acids into Escherichia coli for highly efficient synthesis of proteins with novel func...

🚨Our paper is out! 🥳
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...

it all started years ago with a failed experiment
🧵👇 1/9

Nominations for the June Almeida award for Mid/Senior-Career Women in Cryo-EM are now open! Submit your nomination via this link www.biophysics.org/awards-fundi... by November 14th to recognize an exceptional woman in our community.

Nobel Laureate Joachim Frank: "I will not be bookended by two fascist regimes." An impactful must-read. www.usnews.com/opinion/arti...

Universities in Nazi Germany and the Soviet Union thought giving in to government demands would save their independence Before the Nazis, German universities were among the best in the world. Step by step, the universities gave up their independence until they were instruments of the state.

theconversation.com/universities...

Prizes must recognize machine contributions to discovery The future of science will be written by humans and machines together. Awards should reflect that reality.

My HPLC was definitely overlooked

www.nature.com/articles/d41...

The Rutgers Brain Health Institute @rutgersbhi.bsky.social is looking for an accomplished scientist to serve as the Director of the new Rutgers Center on Research in Pain and Pain Therapeutics. Feel free re-post and/or reach out to me if you have any questions
jobs.rutgers.edu/postings/225...

EXCITING NEWS!! We're searching for a new professor colleague at the Biozentrum🇨🇭. Ideal candidates are exploring novel biological questions with structure, biophysics, or high-resolution imaging. 🧪 🧶🧬 🔬

The call closes Nov 3. Please get in touch if you would like more information. Come join us! 👩‍🔬🤓

We are hiring an Assistant Professor of Biochemistry and Biophysics at Weill Cornell Medicine. Come join our collaborative research environment with state-of-the-art facilities in NYC! Application review starts Oct 22.
biochem.weill.cornell.edu/join-our-fac...

Thank you all the program officers at NIH that persisted through the 2025 fiscal year and were able to fund 99% of the total FY2024 budget. I know this has take a toll on everyone at NIH. Thank you for supporting important health and behavior science and helping to keep the U.S. a leader in science.

What if NIH had been 40% smaller? Replaying history with less NIH funding shows widespread impacts on drug-linked research

This paper does a great job with a "It's a Wonderful Life" scenario about NIH, supposing the consequences of the bottom 40% of the funding NIH grants never existed.

www.science.org/doi/10.1126/...

tl:dr The world would lose a lot, but directly and indirectly

Congratulations, Yifan, for the Anatrace Award! Yifan’s work on the TRPV1 structure with David Julius helped launch the Resolution Revolution in cryo-EM. Not just in membrane proteins—hardly any area of biophysics today has remained untouched by the techniques Yifan pioneered.

Congratulations, Nuria! For many years, Nuria ran the Biochemistry and Biophysics of Membranes study section at the NIH. She trained generations of reviewers and taught many of us how to write a better grant.

🚨🧠🔬 A major breakthrough in molecular neuroscience:

I am excited to share a new story from our lab, published in accelerated format today by @nature.com:

"Delta-type glutamate receptors are ligand-gated ion channels"

Read more here (free article link): rdcu.be/eGIKz

Re-upping this - applications will close - open to UK-based people too!!!

We are hiring! Oxford biology has three associate professorships available as we move to new state-of-the-art facilities

Three Associate Professor (or Professor) positions available at Oxford Biology. Come be my colleague! www.biology.ox.ac.uk/article/we-a...