Clasp Therapeutics

Please join us in welcoming Smrithi Raman to the Clasp team! Smrithi is an MIT Sloan MBA candidate and joins us as our Corporate Development Intern. We’re excited to see the impact she’ll make!
#NewHire #NewClaspian #ClaspTherapeutics

In celebration of Diwali—the festival of light, reflection, and renewal—we’re shining a spotlight on our Chief Scientific Officer, Vipin Suri.
Vipin shares how this season’s spirit mirrors Clasp’s mission: advancing transformative science, staying grounded in purpose, and bringing hope to patients.

We were proud to host our Board of Directors at our Rockville site for a lab tour and reception – an excellent opportunity to showcase Clasp’s science and strengthen connections between our Board and Claspians.
#BoardEngagement

Congratulations to our September Claspie Award winners who embody our core values in their work to help patients.
Justina Caushi, Barbara DeFabio, Candice Linde, Maribel Schutt, Megi Rexhepaj, Nancy Kennedy, and Veselin Dobrev.
#ClaspTherapeutics #Teamwork

Clasp Therapeutics will present a Trial-in-Progress poster at #ESMO25 on Oct 19: GUARDIAN-101, a first-in-human study of CLSP-1025, a first-in-class p53 T cell engager.

Meet Shannon Devens & Lauren Harshman at the poster (12–12:45 CEST) or throughout the conference.

#PrecisionOncology #TCE

Meet the BostInno 2025 Fire Awards honorees - Boston Business Journal Every year, we recognize 50 companies, organizations, or individuals who have had a major impact within the local ecosystem.

Clasp Therapeutics is proud to be a BostInno 2025 Fire Awards honoree in the Biotech category.

Thank you, Boston Business Journal, for this recognition of our work to bring unparalleled precision to immuno-oncology using next-generation T-cell engagers (TCEs).

www.bizjournals.com/boston/inno/...

On Cancer Research Day, Clasp is proud to be part of a community advancing science to bring more precise, effective treatments to people living with cancer. We’re grateful to the researchers, clinicians, patients, and families whose courage makes progress possible.
#CancerResearchDay

We gathered for a Bob Ross–themed painting event, led by our very own 𝘙𝘰𝘣 𝘙𝘰𝘴𝘴! It was the perfect chance to relax, get creative, and uncover some hidden team talent. A joyful, colorful time together!
#ClaspTherapeutics #BobRossVibes #Creativity

Congrats to our August Claspie Award winners! Thank you for driving our mission forward for patients in need!

Kai Li Tan, Jessica Kohler, Kate Stokes, Megi Rexhepaj, Michael Alloway, Ron Copeland, Zack DerBoghosian

#ClaspTherapeutics #Teamwork

As we return from Labor Day, we are spotlighting Jessica Kohler, Director of Immunology at Clasp. Her leadership drives our mission to deliver precision therapies. Jess shares what inspires her, and her advice for the next generation of scientists.
#ClaspianSpotlight

We partnered with American Cancer Society's Hope Lodge in Boston & Baltimore to serve dinner and pack care kits for guests undergoing cancer treatment. Their strength and sense of community inspire us to keep working toward our mission to support patients.
#ClaspingWithCommunity #MakingADifference

Congrats to our June Claspie Award winners!
Veselin Dobrev, Angella Ndagire, Brena Williams, Jeff Smith, Hayden Jones, Lenore Cullen, Kai Li Tan, Madison Curtis Siok, Megi Rexhepaj, Michael Alloway, Mike Maloney, Monika Sharma, Kaleigh Krapfl
#ClaspieAwards

We were honored to host Dr. Timothy Yap of MD Anderson, a key investigator on our GUARDIAN-101 study. He shared powerful patient insights and his excitement about Clasp’s T cell engager approach. We're energized to keep working for life-changing therapies.
#PatientCentric #Biotech

In our third installment of Inside Clasp, we’re excited to introduce CLSP-1025, our lead T-cell engager targeting the p53 R175H mutation, a major oncogenic driver in many solid tumors, including colorectal, pancreatic, and lung cancers.

Learn more: clinicaltrials.gov/study/NCT067...

Congrats to Amanda Ford, Lenore Cullen, Michael Alloway & Veselin Dobrev on their well-deserved promotions! We're proud to work with such passionate and talented team members.

#Congratulations #Promotion #ClaspTherapeutics

Please join us in welcoming Katie Shaver as an In Vitro Immunology Co-op. Katie is currently pursuing a Bachelor of Science in Bioengineering at Northeastern University, with a concentration in Cell & Tissue Engineering. We’re excited to work with Katie!
#NewHire #NewClaspian #ClaspTherapeutics

Clasp celebrates #Juneteenth! We honor the history and support the empowerment of our Black communities. Wishing everyone a meaningful day of reflection through art, education, and community.
#freedom #equality #resilience

Researchers Showcase How AACR Project GENIE is Powering New Insights into Cancer Care Researchers shared how AACR Project GENIE is helping provide insights into rare and early-onset cancers, tumor-agnostic therapy, and more.

We’re excited to share that Clasp was featured in a
@theaacr.bsky.social article highlighting our use of Project GENIE to advance CLSP-1025, our T-cell engager being tested in the GUARDIAN-101 clinical trial.

Watch Kristen McEachern discuss CLSP-1025 and GENIE:
www.aacr.org/blog/2025/06...

Join us in celebrating our May Super Claspie Award winners, @Candice Linde and @Maribel Schutt! Their collaboration and innovation brought to life a fun, engaging offsite for our Claspians. Thank you for your hard work!

#ClaspTherapeutics #Teamwork #AppreciationAndCelebration

Clasp had a blast at Bio-Ball 2025! Grateful to have shared the court with the Special Olympics athletes, and our fellow biotech teams. Thanks to our players, cheerleaders & the event organizers!
#BIOBALL2025 #SpecialOlympics #BiotechForGood

June marks Cancer Immunotherapy Month—a perfect time to spotlight our pHLAre™ T-cell engagers, which are designed to precisely target cancer-driving mutations for immune attack while sparing healthy tissue. Part 2 of 2. #CancerImmunotherapyMonth #PrecisionOncology

June marks Cancer Immunotherapy Month—a perfect time to spotlight our pHLAre™ T-cell engagers, which are designed to precisely target cancer-driving mutations for immune attack while sparing healthy tissue. Part 1 of 2. #CancerImmunotherapyMonth #PrecisionOncology

This Pride Month, Clasp honors the diversity, strength & achievements of the LGBTQ+ community. Let’s keep building a world of acceptance, equality & belonging - every day. Happy Pride! 🏳️‍🌈❤️
#Pride2025 #EqualityForAll #InclusionMatters #CelebrateDiversity

On National Cancer Survivors Day, we celebrate the strength and resilience of everyone touched by cancer. Your courage drives progress toward better treatments. Thank you to survivors, caregivers, and advocates for leading the way. #CancerSurvivorsDay #Hope

Congratulations to our April Claspie Award winners! They embody our core values, and we’re proud to work alongside them. Thank you for your hard work, passion, and dedication!

Super Claspie – Julia Shepherd

Claspies – Alec Andrews, Barbara DeFabio, Brena Williams, Catherine Souza, Mike Maloney

At our first 2025 offsite, we hosted Dr. Kristen Hege who shared powerful lessons from her Pacific Crest trail hike. Dr. Hege is fundraising for women in science – read more and donate here:
socialfundraising.apps.upenn.edu/socialFundra...

#TeamConnection #CompanyCulture

In honor of National Cancer Research Month, Clasp is focused on unlocking cancer’s weakness. Our T-cell engagers precisely target cancer driver mutations, activating the immune system while minimizing off-target effects.

#NationalCancerResearchMonth #TCellEngagers #PrecisionMedicine

Clasp honors the compassion, resilience, and expertise of oncology nurses. Their dedication to patients during life’s most difficult moments plays a critical role in advancing cancer care. We’re grateful to work alongside these heroes in our mission to improve the lives of those affected by cancer.

In honor of Asian American and Pacific Islander (AAPI) Heritage Month, Clasp celebrates the rich cultures, histories, and contributions of the AAPI community, including the many scientists, innovators, and leaders who have helped shape the life sciences and biotech industries.
#AAPIHeritageMonth

Two major CLSP 1025 milestones today: dosing the first patient in the first trial of a precision T cell engager targeting a driver mutation and unveiling nonclinical data at AACR supporting our Phase 1 design.

More details:

www.clasptx.com/press-releas...

www.clasptx.com/press-releas...