Biophysical Reports

CD spectra reveal the state of G-quadruplexes and i-motifs in repeated and other DNA sequences The B-DNA of the genome contains numerous sequences that can form various noncanonical structures including G-quadruplex (G4), formed by two or more stacks of four guanine residues in a plane, and…

Check out an article from our most read list: "CD spectra reveal the state of G-quadruplexes and i-motifs in repeated and other DNA sequences" (Levi Diggins et al.)

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Reaction-Diffusion Model for Brain Spacetime Dynamics In our research, we use a reaction-diffusion model to simulate brain spacetime dynamics. The model is inspired by theoretical physics, and the FitzHugh-Nagumo model is used to simulate neural…

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Single-molecule localization microscopy error is sensor dependent and larger than theory predicts Since the advent of stochastic localization microscopy approaches in 2006, the number of studies employing this strategy to investigate the subdiffraction limit features of fluorescently labeled…

Check out an article from our most read list: "Single-molecule localization microscopy error is sensor dependent and larger than theory predicts" (Alfonso Brenlla et. al.)

Call for Applications: Editor-in-Chief of Biophysical Journal The Biophysical Society is seeking the next Editor-in-Chief of the Society’s flagship publication, Biophysical Journal. This appointment will begin January 1, 2027, for one five-year term. The…

Biophysical Journal seeks candidates to be its next Editor-in-Chief beginning in 2027. Applications and nominations will be accepted until March 1. More information is available at buff.ly/fkiDDQg.

Call for Applications: Editor-in-Chief of Biophysical Journal The Biophysical Society is seeking the next Editor-in-Chief of the Society’s flagship publication, Biophysical Journal. This appointment will begin January 1, 2027, for one five-year term. The missio...

Biophysical Journal seeks candidates to be its next Editor-in-Chief beginning in 2027. Applications and nominations will be accepted until March 1. More information is available at www.biophysics.org/blog/call-for-applications-editor-in-chief-of-biophysical-journal.

Call for Applications: Editor-in-Chief of Biophysical Journal The Biophysical Society is seeking the next Editor-in-Chief of the Society’s flagship publication, Biophysical Journal. This appointment will begin January 1, 2027, for one five-year term. The missio...

Biophysical Journal seeks candidates to be its next Editor-in-Chief beginning in 2027. Applications and nominations will be accepted until March 1. More information is available at www.biophysics.org/blog/call-for-applications-editor-in-chief-of-biophysical-journal.

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Platelets feel the squeeze. Rodriguez et al. use optical microscopy, scanning ion conductance microscopy and microcontact printing to mimic narrow vessels in vitro, revealing how spatial confinement alters platelet shape, spreading dynamics, and mechanics.

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Quantification of mechanical-cytoskeletal coupling in human corneal cells across myopia severity Myopia is a prevalent refractive eye disorder closely associated with alterations in corneal biomechanical properties. As fundamental units of corneal tissue, corneal cells significantly influence…

Junyuan et al. use AFM to uncover how corneal cells influence myopia progression, showing that cytoskeletal disorganization causes corneal cells to become softer and more adhesive as myopia worsens.

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Peer Review Week (PRW) is a global celebration of the vital role peer review plays in ensuring the quality and integrity of research. Peer Review Week (PRW) is a global celebration of the vital role peer review plays in ensuring the quality and integrity of research.

During Peer Review Week, Biophysical Journal thanks all the reviewers and editors who make our journal possible! See events taking place at peerreviewweek.net. #PRW2025
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Online now! Scanning electron microscopy of hyphal ectobiont bacteria within mycelial extracellular matrices. Davin Browner and Andrew Adamatzky. www.cell.com/biophysrepor...

Know the Editor What are you currently working on that excites you? I’ve always been fascinated by how protein dynamics relate to function. In our ongoing research on a family of allosteric enzymes, we uncovered…

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Reaction-Diffusion Model for Brain Spacetime Dynamics In our research, we use a reaction-diffusion model to simulate brain spacetime dynamics. The model is inspired by theoretical physics, and the FitzHugh-Nagumo model is used to simulate neural activity...

Read about the cover art for the newly released issue of Biophysical Reports on the BPS Blog: www.biophysics.org/blog/reactio...

Skeletal Muscle Alpha Actin (ACTA1) Acetylation Enhances Myosin Binding and Increases Calcium Sensitivity Skeletal muscle alpha actin (ACTA1) is important for muscle contraction and relaxation, with historical studies focused on ACTA1 mutations in muscle dysfunction. Proteomics reports have consistently o...

Online now! Skeletal Muscle Alpha Actin (ACTA1) Acetylation Enhances Myosin Binding and Increases Calcium Sensitivity.
Samantha S. Romanick, Luis Godoy, Adrian Lopez, Allison Matsumura, Kiana Boc, Travis J. Stewart, Josh E. Baker, and Bradley S. Ferguson. www.cell.com/biophysrepor...

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Escherichia coli FocA/B-dependent H+ and K+ fluxes: influence of exogenous versus endogenous formate Escherichia coli translocates formate/formic acid bidirectionally across the cytoplasmic membrane by the FocA/FocB formate channels during fermentation. Depending on the pH and whether formate is…

Online now! Escherichia coli FocA/B-dependent H+ and K+ fluxes: influence of exogenous versus endogenous formate. L. Grigoryan, A. Babayan, A. Vassilian, A. Poladyan, G. Sawers, and K. Trchounian.