Figure 1. SWEET pilot study design.
Can #sucralose enhance #Treg cells? The SWEET trial investigates! #transplant @facmed-umontreal.bsky.social l @csnscn.bsky.social @cjkhd.bsky.social
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@cjkhd.bsky.social
CJKHD, the official journal of CSN. We publish fundamental science and clinical science in the field of kidney health. Based in Canada|Turtle Island, we recognize our reparative responsibility to uplift the knowledges and expertise of Indigenous peoples.
Figure 1. SWEET pilot study design.
Can #sucralose enhance #Treg cells? The SWEET trial investigates! #transplant @facmed-umontreal.bsky.social l @csnscn.bsky.social @cjkhd.bsky.social
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Overview of the KRESCENT core curriculum revamp process
See how @CIHR funding via the novel #HRTP grant evolved the core #KRESCENT 2.0 curriculum π
#futurenephrologists #trainingprogram
@csnscn.bsky.social @cjkhd.bsky.social @ualberta.bsky.social @ubcmedicine.bsky.social
Can-SOLVE CKD pathway to implementation.
Improving access to living #kidneydonor transplantation: a #patientoriented approach to living donor and transplant processes.
#organawareness @lhsccanada.bsky.social a @csnscn.bsky.social
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Beyond the Equation: A Call for Sustained Equity in #CKD Care for Black Communities. β€οΈ #EDI #BlackHealthMatters @sunnybrookhsc.bsky.social @csnscn.bsky.social
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Conceptual framework of effect of intradialytic exercise on patient-important outcomes.
#Cardioprotective intradialytic exercise training may protect against hemodialysis-induced myocardial stunning, and improve patient-important outcomes #patientcare #AskRenal @umanitoba.bsky.social @csnscn.bsky.social
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Overview of categories and subcategories pertaining to patient and caregiver transplant experiences.
Kidney #transplantation in children with #kidneydisease: navigating the experiences and educational needs of patients and caregivers π¨βπ©βπ§βπ¦ #pediatricnephrology @usask.ca @sagepub.com @csnscn.bsky.social
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Kidney biopsy findings at initial diagnosis of thrombotic microangiopathy (A, B) and postoperative renal cortical necrosis (C, D, E). Initial kidney biopsy reflecting thrombotic microangiopathy: (A) Glomerulus showing features of acute thrombotic microangiopathy: dilated capillary loops, mesangiolysis (white star) and fibrin thrombus (white arrow). In addition, periglomerular fibrosis due to chronic hypoperfusion. PAS 40Γ. (B) Ultrastructural features of chronic microangiopathy: subendothelial widening by fluffy proteinaceous material separating the endothelial cell from the GBM (white star) and forming double contours (white arrow). Endothelial cell hypertrophy (orange star) (TEM 20000Γ). Postoperative kidney biopsy: (C) Extensive necrosis (coagulative) with interstitial hemorrhage (white arrows). (H&E 20Γ). (D) Coagulative necrosis, interstitial inflammation (white arrows) in areas of reperfusion (H&E, 20Γ). (E) Extensive cortical necrosis (H&E 4Γ).
A #casereport and #literaturereview of renal cortical necrosis due to antiphospholipid syndrome. π¬ #biopsy #necrosis #AKI @unityhealthto.bsky.social @csnscn.bsky.social
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CSN-QUIS nephrology fellow QI curriculum.
The CSN-QUIS committee is expanding the QI curriculum for Nephrology trainees in Canada π¨π¦. #trainingprograms #positiveexperience #implementationscience
@csnscn.bsky.social @dalhousieu.bsky.social @sagepublishing.bsky.social
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CKD prevalence varies across Latin America. Among individual studies: Argentina 24.16%, Haiti 27.14%, Nicaragua 9.14%, Peru 16.83%, Panama 12.00%, Cuba 9.63%, Ecuador 7.26%. In countries with multiple studies: Brazil 13.91%, Mexico 20.79%, El Salvador 15.31%, Chile 20.58%. #CKD #Epidemiology
Our systematic review suggests #CKD is a growing challenge in Latin America, with a prevalence of 15.9%.
Global diagnostic criteria and prevention strategies for vulnerable populations are urgently needed. #KidneyHealth #Epidemiology @csnscn.bsky.social @sagepub.com
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PRECIS-2 wheel highlighting the pragmatism of the Dial-Mag trial for 9 domains.
A pragmatic trial to inform center-wide policy on the optimal dialysate magnesium concentration for patient health. #hemodialysis #DialMag #healthcare @csnscn.bsky.social
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Figure 1. Main themes and practical considerations when implementing incremental hemodialysis.
Patientsβ and healthcare providersβ experiences with incremental #hemodialysis: our qualitative study outlines benefits, challenges, and practical recommendations for safe implementation. #MUHC #Nephrology #QualityofLife
@mcgilluniversity.bsky.social
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Summary of components of the protocol-based fluid management prescription.
A pragmatic trial to inform center-wide policy on the optimal dialysate magnesium concentration for patient health. #hemodialysis #DialMag
@crchum.bsky.social
@csnscn.bsky.social
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Prevalence of individuals with a multidisciplinary visit under the GN model of care.
Filling the gaps in #glomerulonephritis care: Ontario Renal Networkβs new multidisciplinary model to improve access to timely and effective multidisciplinary GN care. #OntarioHealth
@sunnybrookhsc.bsky.social @cjkhd.bsky.social
@csnscn.bsky.social
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Desmopressin for #kidneybiopsy in patients with #CKD has efficacy for reducing bleeding outcomes. Despite this, it does not completely mitigate the increased bleeding risk of lower GFR levels (β€stage 3b) and is not a panacea for this outcome. @csnscn.bsky.social
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Person-level or individual factors that contribute to inequitable impacts of disasters
From Risk and Vulnerability to Preparedness and Resiliency: An Opinion Piece on Championing Disaster and Emergency Risk Reduction and Management in #KidneyCare. @csnscn.bsky.social @cjkhd.bsky.social @mcgilluniversity.bsky.social
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Multifaceted QI intervention to reduce time to transplant listing
A QI intervention showed early signs of success in reducing time to #kidneytransplant listing and improved access for #Indigenous patients at an academic tertiary care center. @mcgilluniversity.bsky.social @cjkhd.bsky.social @csnscn.bsky.social
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Self-reported nephrology fellow kidney POCUS skill level. (A) Pre-workshop, (B) Post-workshop.
#Nephrology fellows trained in #POCUS can detect hydronephrosis & small kidneys with high specificity!
A structured workshop improves confidence, speeds up imaging,& enhances patient satisfaction #kidneyweek @unityhealthto.bsky.social @csnscn.bsky.social @cjkhd.bsky.social
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Figure 2. A summary of the key insights gained during this participatory research that helped inform the methods of a large multinational qualitative research study that we will undertake to unpack the contributors of gender disparity in living kidney donation in different societies and health systems.
Unpacking the contributors of #genderdisparity in living #kidneydonation in different societies and health systems: key insights gained @csnscn.bsky.social @mcgilluniversity.bsky.social
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A table with columns headers βthemeβ and βsupporting statementβ. The theme column list the major themes found in the study interviews. The supporting statements column list examples of participant quotes that describe the associated theme.
Weight management in #CKD patients is key to transplantation eligibility. 12 patients discuss lack of support, family eating habits, endurance, and values of quality of life as key factors to consider. #kidneydisease #obesity @westernu.ca @csnscn.bsky.social
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Summary of sex and gender characteristics of adults on hemodialysis experiencing depression and depressive symptoms (n = 25).
A scoping review found more differences than similarities in #sexandgender related to depression in #hemodialysis patients. Notably higher rates of #depression was observed in females. #kidneyfailure @csnscn.bsky.social @cjkhd.bsky.social @ualberta.bsky.social
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Reasons for non-usage of evidence-based therapies in the C.a.R.E clinic.
Barriers to uptake of evidence-based therapies in the C.a.R.E clinic. @UHN @CSNSCN #kidneyhealth #MedEd
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The CanSolveCKD team is adapting mykidneysmyhealth.com to better support diverse communities with #CKD. Through patient-oriented research, Indigenous engagement & inclusive design, they're improving access, cultural relevance & sexual health support @csnscn.bsky.social
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This pragmatic randomized control trial determined whether the addition of a virtual monitoring platform can reduce emergency department visits and hospitalizations in advanced #CKD patients. @csnscn.bsky.social @umanitoba.bsky.social
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A #NarrativeReview identifies key barriers that limit the donation of #kidneygrafts after death and proposes different initiatives for potentially expanding the donor pool. #organdonation @mcmasteruniversity.bsky.social @sickkidsto.bsky.social @csnscn.bsky.social
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This figure shows the therapies used by individuals classified as having moderate-to-severe CKD-aP. Of those with moderate-to-severe CKD-aP, 29% were using over-the-counter medications, 1% were using cannabinoids, 9% were taking prescribed Gabapentin or Pregabalin, and 18% were using a combination of these therapies (of these patients 1 was prescribed antihistamines in addition to other treatments). 42% were using no treatments.
The impact of #chronickidneydisease -associated pruritus on quality of life, gaps in care, and the importance of systematic symptom screening. #dialysis @queensuresearch.bsky.social @csnscn.bsky.social
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Figure 4. Mean serum 25(OH)D levels from supplement vs non-supplement groups.
Calcium isnβt just about bones. In dialysis patients, high serum calcium with low #vitaminD meant weaker muscles; supplements helped. Time to rethink calciumβs neuromuscular role. #CalciumMetabolism #Nephrology #Sarcopenia @cjkhd.bsky.social @csnscn.bsky.social
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Figure 2. Montreal cognitive assessment (MoCA).
A #clinicalresearch protocol looks at the prevalence of cognitive impairment in patients undergoing hemodialysis using #VirtualReality cognitive testing
@umanitobasci.bsky.social @dalhousieu.bsky.social @csnscn.bsky.social
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Figure 1. The KRESCENT mentorship team spans across jurisdictions, sectors, and disciplines. 1. Todd Alexander (NPA). KRESCENT Program Director. 2. Adeera Levin (PA), KRESCENT leadership since inception. 3. Sunny Hartwig (PA), KRESCENT Curriculum Chair and KRESCENT alumna. 4. Julie Ho (PA), KRESCENT alumna. 5. Leanne Stalker (PA), Scientific Director of KFoC. 6. Janine Farragher (PA), ECR and KRESCENT alumna. 7. Mary Beaucage (PA), Patient Council member. 8. Kara Schick-Makaroff (PA), KRESCENT alumna. 9. Malcolm King (PA) Indigenous Scholar and former head of the CIHR Institute of Aboriginal Health. 10. Sanjay Pandeya (PA), President of the CSN. 11. Karthik Tennankore (PA). 12. Ana Konvalinka (PA), KRESCENT alumna. 13. Kevin Burns (PA), KRESCENT Founder and former Director. 14. FranΓ§ois Madore (PA). 15. Nina Jones (Co-App), KRESCENT alumna. 16. Robert Quinn (Co-App). 17. Lisa Robinson (Co-App) EDI Champion. 18. Morteza Ahmadi (Co-App), KRESCENT alumni entrepreneur. 19. Mitch Abrams (Co-App).
The KRESCENT 2.0 Health Research Training Platform grant process represents a pan-Canadian effort to fund the next generation of kidney scientists through the KRESCENT platform. #kidneydisease #kidneydiseaseawareness #kidneyhealth @csnscn.bsky.social @cjkhd.bsky.social
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A comparative summary of KRESCENT training offerings - from beginning to present (KRESCENT 1.0 to 2.0)
KRESCENT; 2005 -2025 β 20 years! Editorial
#CureKidneyDisease #KRESCENT #Mentoring
@csnscn.bsky.social @cjkhd.bsky.social @ualberta.bsky.social
@ubcmedicine.bsky.social
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Table 1. Cox-Regression Analysis of Kidney-Related Outcomes After Prescription of Anti-Hyperglycemic Medications.
Cox-regression analysis of kidney-related outcomes after prescription of anti-hyperglycemic medications.
#diabetes #kidneydisease #protection @csnscn.bsky.social @cjkhd.bsky.social @ualberta.bsky.social
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