Many congratulations!
04.08.2025 07:10 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0@scale-cluster-ffm.bsky.social
We are a Cluster of Excellence (EXC) based in Frankfurt, Germany, that explore the SubCellular Architecture of LifE. Our goal is to understand how the organizational principles within cells give rise to functional biological outcomes.
Many congratulations!
04.08.2025 07:10 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0๐ Ribosomes on the road! New research from the Schuman Lab @mpibrain.bsky.social shows neurons can locally assemble ribosomes - far from the nucleus and close to synapses. A big shift from textbook biology! ๐๐งฌ๐ bit.ly/3GUJKPv #Neuroscience #CellBiology #Ribosomes
01.08.2025 13:39 โ ๐ 14 ๐ 4 ๐ฌ 1 ๐ 0๐ฌ This research uncovers how the splicing factor SRSF5 helps coordinate the interaction between two neighboring nuclear structuresโnuclear speckles (NS) and paraspeckles (PS)โparticularly during cellular stress.
28.07.2025 13:21 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0๐Congratulations to @mixmue.bsky.social, @heilemannlab.bsky.social, and all co-authors on their recent publication in Nucleic Acids Research!
Proud to see this work arise from the collaborative efforts of SCALE faculty, including Stefan Mรผller and Dorothee Dormann.
academic.oup.com/nar/article/...
Prof. Franziska Matthรคus in der๐Ausgabe des unireport @goetheuni.bsky.social ehem. ๐ฃ๏ธvonโก๏ธLOEWE-CMMS @fias.bsky.social zu ยปCritical Computational Literacy @ GU Future Skills and Beyondยซ einem๐ Lehrangebot zu KI & Coโก๏ธ www.unireport.info/176087817/un... mehr zu Matthรคusโก๏ธ proloewe.de/de/persoenli...
18.07.2025 08:37 โ ๐ 6 ๐ 2 ๐ฌ 0 ๐ 0Left: LaBeRling contact sites between the plasma membrane (green) and the endoplasmic reticulum (magenta). Contacts are highlighted in blue using LBR. Image created by Laura Downie. Right: 3D render of a membrane contact site (orange) between a mitochondrion (pink) and the ER (green contours). Image created by Stephen Royle.
#ER - #membrane contact sites are often distorted by existing labeling methods. @steveroyle.bsky.social &co present an inducible labeling system (LaBeRling) using #LaminB receptor to fluorescently tag ER-membrane contact sites in live cells, preserving morphology @plosbiology.org ๐งช plos.io/4lv6gxu
11.07.2025 13:27 โ ๐ 26 ๐ 9 ๐ฌ 0 ๐ 0๐๐ผ @tuda.bsky.social
17.07.2025 12:45 โ ๐ 1 ๐ 1 ๐ฌ 0 ๐ 0Proud to share our first lab pre-print: โSND3 is the membrane insertase within a fungal multipass transloconโ where @tzujingyang.bsky.social solved the structure of a ribosome-associated SND3-translocon complex involved in ER membrane protein insertion โก๏ธ doi.org/10.1101/2025...
12.07.2025 00:49 โ ๐ 89 ๐ 32 ๐ฌ 3 ๐ 4Many congratulations to @MpiBrain Director Erin Schuman @erin-schuman.bsky.social on receiving the 2026 Nakasone Award! ๐ง @hfspo.bsky.social ๐
11.07.2025 08:16 โ ๐ 6 ๐ 0 ๐ฌ 0 ๐ 0HIV-1 nuclear import is selective and depends on both capsid elasticity and nuclear pore adaptability pubmed.ncbi.nlm.nih.gov/40624219/ #cryoEM
08.07.2025 17:02 โ ๐ 5 ๐ 5 ๐ฌ 0 ๐ 0Prof Thomas Prisner awarded the 2025 Richard R. Ernst prize in magnetic resonance at EUROMAR 2025 in recognition of pioneering contributions to biomolecular research through advances in EPR and DNP methodologies @brukercorporation.bsky.social #NMRnews #NMRchat #NMR #Euromar2025 ๐งฒ
07.07.2025 12:43 โ ๐ 13 ๐ 2 ๐ฌ 1 ๐ 1This illumination protocol enabled structural snapshots of both the dark and intermediate states, linking the prolonged photocycle to a flip of the unique residue R57 that defines CryoRhodopsins.
๐ Science Advances: www.science.org/doi/10.1126/...
Alternating illumination with either green or blue light allows for an efficient interconversion between the dark state and this blue absorbing intermediate state, as observed for molecular photoswitches.๐งต
07.07.2025 15:03 โ ๐ 0 ๐ 0 ๐ฌ 1 ๐ 0Due to its blue color under acidic conditions, CryoR1 is set to absorb red light, a feature rarely found in nature. Under neutral to alkaline conditions, CryoRhodopsins in general possess a photocycle that lasts for minutes, including the prominent formation of an UV absorbing intermediate state. ๐งต
07.07.2025 15:03 โ ๐ 0 ๐ 0 ๐ฌ 1 ๐ 0๐ Structural: K. Kovalev @embl.orgโฌ Hamburg, Prof. A. Guskov @rug.nl
โ๏ธ Functional: Prof. T. Moser @UMC Gรถttingen
๐ Spectroscopy: @wachtveitl-lab.bsky.social @goetheuni.bsky.social ๐งต
๐ Special congratulations to the first authors: Gerrit Lamm, Egor Marin, and Alexey Alekseev.๐งต
07.07.2025 15:03 โ ๐ 1 ๐ 0 ๐ฌ 1 ๐ 0๐ง๐ฆ CryoRhodopsins โ a newly discovered clade of microbial rhodopsins found only in cold environments โ absorb red light under acidic conditions and behave like molecular photoswitches!
Discovered by an interdisciplinary team led by SCALE PI Prof. Dr. Josef Wachtveitl.๐งต
Many congratulations!
07.07.2025 11:13 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0Congratulations!
07.07.2025 11:12 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0Workshop Alert: On July 10, Nathalie Weickgenannt and Laura Buglioni from @angewandtechemie.bsky.social will be at Goethe University Frankfurt to host a Wiley Publishing Workshop. Donโt miss this opportunity to gain valuable insights into scientific publishing!
03.07.2025 21:03 โ ๐ 4 ๐ 3 ๐ฌ 0 ๐ 0Finally out in Nature Chem Bio:
SNAP-tag2 for faster and brighter protein labeling
www.nature.com/articles/s41...
Thank you Steffi and Veselin.
Seminar Alert:
Prof. Igor Ulitsky, PhD
Weizmann Institute of Science
Date: 21.07.2025. 3 pm
Venue: Faculty of Medicine, Goethe University, Seminar room 1, Haus 22 (S22-1)
@igorulitsky.bsky.social @cpi-exstra.bsky.social @scale-cluster-ffm.bsky.social @goetheuni.bsky.social
๐ Thanks to host Michaela Mรผller-McNicoll @mixmue.bsky.socialโฌ, keynote speakers Phillip Stansfeld & @michriscopy.bsky.socialโฌ, and the amazing team behind the scenes.
๐ธ Photo by Uwe Dettmar
๐ More: lnkd.in/ecx8qUNZ
๐ Dr. @jakobsilberberg.bsky.socialโฌโ Interdisciplinary Work
๐ Dr. @zoliviapg.bsky.social โ Method Development
๐ Dr. @huaipengxing.bsky.socialโฌ โ Scientific Contribution๐งต
๐ The SCALE-it Best PhD Award 2025 celebrated groundbreaking doctoral research shaping the future of science!
From interdisciplinary innovation to pioneering methods & major scientific contributions โ we honored early-career researchers pushing the boundaries:๐งต
New publication in @narjournal.bsky.social - Using NMR, SAXS & MD, we characterize the dynamic nonaloop of the SARS-CoV-2 Delta s2m RNA, contributing to future ensemble-functional studies of dynamic RNA motifs.
Full text: doi.org/10.1093/nar/...
#RNA #StructuralBiology #NAR #NMR #MDSimulations
www.nature.com/articles/d41... #heartmusclecells :)
28.06.2025 20:52 โ ๐ 2 ๐ 1 ๐ฌ 0 ๐ 0We are very happy to invite you to our 9th Rhineland RNA Club at @dzne.science Bonn with great local speakers and Lena Steckelberg @lenasteckelberg.bsky.social as our invited speaker. All #RNA enthusiasts are welcome! Organized by @inahuppertz.bsky.social and @katleppek.bsky.social. #RNAsky
24.06.2025 16:56 โ ๐ 12 ๐ 6 ๐ฌ 1 ๐ 1@goetheuni.bsky.social @rheinmainunis.bsky.social @mpibp.bsky.social @mpibrain.bsky.social #FIAS
25.06.2025 12:15 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0