Aleksandra Deczkowska

🧠 The Lipid #Brain Atlas is out now! If you think #lipids are boring and membranes are all the same, prepare to be surprised. Led by @lucafusarbassini.bsky.social with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution.
www.biorxiv.org/cgi/content/...

Fwd: Fwd: “I hope this email finds you well”

Forme sanguine de Trypanosoma brucei, parasite flagellé responsable de la maladie du sommeil en l'Afrique Centrale. Microscopie électronique à balayage. Crédit : Institut Pasteur/Thierry Blisnick, unité Biologie cellulaire des Trypanosomes. Acquisition à la Plate-Forme de Microscopie Ultrastructurale

SHERLOCK4HAT: a CRISPR-RNA test rapidly spots animal trypanosomes, boosting sleeping-sickness surveillance and protecting herds. Led by Institut Pasteur & partners, study in eLife.

Details: www.pasteur.fr/en/home/rese...

#PressRelease 🗞️ The oldest workshop for making shell jewellery has been unearthed at the Palaeolithic site of La Roche-à-Pierrot. 🐚

👉 www.cnrs.fr/en/press/old...

“WHERE IS THE SOUL” by Aline Zalko, a set of paintings by a fantastic Parisian painter and illustrator, and a product of some hours of discussion about the brain, mind, soul, brain borders, determinism and so much more. Now displayed @pasteur.fr

Some thoughts on meningeal mast cells inspired by Xinzhong Dong and @jonykipnis.bsky.social recent (and AWESOME) papers. Lead: @fakesamir.bsky.social

www.cell.com/trends/immun...

Keep your neutrophils close, but your mast cells closer Immune activity at the cerebrospinal fluid (CSF)–dura–brain interface regulates key functions of brain physiology. In two back-to-back papers, Mamuladze et al. and Kothari et al. show that dural mast cells (MCs) are strategically positioned to coordinate this regulation, controlling CSF flow dynamics and immune cell trafficking in allergy, meningitis, and stroke.

Keep your neutrophils close, but your mast cells closer #immunology

Really interesting study showing learning of tool use in carrion crows! www.cell.com/current-biol...

🍽️🧬 How do diet and gut microbes shape fertility across generations? 🪱🔬 Our Laboratory at #InstitutPasteur is recruiting a PhD student to study epigenetic inheritance of fertility using C. elegans. Fully funded via the International PPU program. Apply now! 🌍 #PhDposition #Epigenetics #Inheritance

Sensory neurons shape local macrophage identity via TGF-β signaling Specialized macrophages are known to persist within tissue niches, but the molecular mechanisms guiding their sustained functional adaptation remain unclear. Kolter and Döring et al. show that local interactions between sensory nerves and macrophages activate TGF-β, which imprints and maintains nerve-associated macrophages that contribute to regeneration after tissue injury.

Another great paper adding to our understanding of macrophage-neuron interactions shaping myeloid and nerve identity (here via TGFb signalling). Led by @philipp359.bsky.social from Freiburg. Out now open access in @cp-immunity.bsky.social:

The last gift: How bodies donated for research may help find a cure for HIV Pioneering project uses “rapid autopsies” to find virus hideouts in infected people

I started research for this story, which came out today, more than a year ago. Thanks to all who stuck with me, and shared their thoughts. www.science.org/content/arti...

Childhood eczema linked to mother’s stress during pregnancy The causes of early-life eczema have been unclear, but evidence indicates that changes to fetal immune cells and sensory neurons during pregnancy play a key part.

The causes of early-life eczema have been unclear, but evidence indicates that changes to fetal immune cells and sensory neurons during pregnancy play a key part

go.nature.com/45Y9aUQ

So what I though was another catalog of antibodies was actually an issue of NRI with a cover inspired by our article!

Summer 2025: early emergence of chikungunya in mainland France An unprecedented situation has arisen this summer, with the first locally acquired cases of chikungunya detected as early as June, notably affecting the Grand Est region for the very first time. Chiku...

France faces unprecedented chikungunya outbreak with first locally acquired cases detected in June - earliest on record. #chikungunya ↘️

Which mosquitoes pose a risk? Species, main diseases and high-risk regions From the tiger mosquito, now well established in Europe, to endemic species in the tropics or Pacific region, these insects have colonized vast areas of the planet and play a key role in local ecosyst...

🦟 From tropical islands to urban Europe, mosquitoes are adapting - and spreading diseases. Of 3,500 species, only ~100 bite humans, but some, like Aedes albopictus, can transmit dengue, chikungunya or Zika. Understanding vector competence is key to stopping outbreaks. ↘️

the destiny spoke - this summer at @aleksdelab.bsky.social we are preparing some awesome manuscripts! can’t wait to share the data in the fall 😎

The innovation trade-off: how following superstars shapes academic novelty - Humanities and Social Sciences Communications Humanities and Social Sciences Communications - The innovation trade-off: how following superstars shapes academic novelty

"our results indicate that academia pays a price by focusing attention and resources on superstars"

Nice to see this supported by data analysis, now.

H/T: @cxdig.bsky.social

www.nature.com/articles/s41...

There is much enthusiasm, in principle, for adversarial collaborations (ACs), a scientific conflict resolution technique that encourages investigators with clashing models to collaborate in designing studies that test competing predictions. Adversarial collaborations offer the promise of breaking deadlocked debates, resolving disputes, and providing a deeper, more comprehensive understanding of a research domain. In practice, however, adversarial collaborations are more the exception than the rule, and there is almost no evidence on how scholars who have ventured into ACs assess the experience. To understand these perspectives, we surveyed and interviewed 29 scholars who participated in 13 AC projects. The data revealed that interpersonal conflicts were generally minor, that these projects required more upfront effort than typical collaborations, but benefited from high-quality results and more thoughtful post-publication debates. Rather than producing a clear “winner,” the most common outcome was a deeper understanding of the problem space through the integration of opposing perspectives. Although the generalizability of these findings is limited by a sample consisting only of scholars who completed an AC, they nonetheless highlight the value of ACs as a tool for advancing scientific inquiry and offer practical guidance for scholars and journals exploring this approach.

29 scholars reflect on their participation in adversarial collaborations:

“Rather than producing a clear 'winner,' the most common outcome was a deeper understanding of the problem space through the integration of opposing perspectives”

Open Access: doi.org/10.1007/s111...

#MetaSci #Methodology 🧪

A timely, argument on why we still animal research now when AI can write songs:

YouTube video by European Commission From Ancient Bones to Modern Insights: Argentinian Scientist Uncovering History of Disease in Paris

www.youtube.com/watch?v=hMH1...

I am very thankful to the @ec.europa.eu for highlighting my research at @institutpasteur.bsky.social . It is a privilege for me to have the opportunity of developing my professional life here.

We were there too! @aleksdelab.bsky.social

4 research institute march together hand in hand for diversity and inclusion in science © Franck Aubry

© Franck Aubry

© Franck Aubry

🌈 United for diversity in science 🌈
Researchers from Institut Pasteur joined the 2025 Pride March alongside @institutcurie.bsky.social, Les Cordeliers Research Center, @institutcochin.bsky.social @institutimagine.bsky.social

👩‍🔬 Because diverse labs make better science.
#DiversityInScience

Can You pls add me too?

How innate immunity starts? Early embryos eliminate bacterial infections by epithelial phagocytosis, a conserved process from zebrafish to human embryos. Check our story:
www.cell.com/cell-host-mi...

🧬 L'Institut Pasteur fait peau neuve !

Nouvelle plateforme de marque, nouvelle identité visuelle, nouvelle signature : "Pour chaque vie, la science agit" 💙

#InstitutPasteur

What a rich life! Very sorry for Your loss, Ardem…

🚨 Get EXCITED — We are just *ONE WEEK* away from #PNIRS2025!!! 👏🏼🤩

Are you ready to bookmark our final #highlights?

📌 Member-Sponsored Symposia 5 & 6
🗓️ Thu, Jun 12 8:30–10 AM

For Details >> 🧵

Spread 👏🏼 the 👏🏼 word 👏🏼

#PNIRS #PNI #Psychoneuroimmunology #Science #France #Bordeaux 🇫🇷

📌Symposium 5
Neuroimmune Signaling at the Borders of the Nervous System: Implications for Physiology and Pathology
🎙️ Peter Grace, Aleksandra Deczkowska, Antoine Louveau

@adeczkowska.bsky.social

#PNIRS2025 #PNIRS

Had the pleasure of listening to @ardemp.bskyverified.social’s lecture yesterday at @pasteur.fr - and seeing a live demonstration of the Piezo tattoo !

How can immune cells shape the brain remotely? Aleksandra Deczkowska @aleksdelab.bsky.social taking us through a wealth of new data exploring Body-brain communication at the choroid plexus
#neurogen25
@nereokalebic.bsky.social @harschnitz.bsky.social @humantechnopole.bsky.social
@r3rt0.bsky.social