Catalina Cuellar-Gempeler

AI Keeps Failing at Microbiome Prediction Why simple models keep winning, where deep learning still shines, and where the field is headed

AI has huge promise for genomics -- but it has consistently failed at microbiome-based prediction.

My new post on why simple models keep winning, where deep learning actually earns its place, and where the field is headed

blekhman.substack.com/p/ai-keeps-f...

I fucking hate proline so fucking much it's the worst amino acid it's so fucking stupid it's incapable of being fucking normal so it forms an ugly ass ring with itself with its own fucking nitrogen cuz it's a loser fucking amino acid I hate it so much I'd rather cut off my right tit than have to ever draw a mechanism with proline ever again

Remember that everyone you meet is fighting their own battle, sometimes with amino acids

Slime mold may be among the best part of my feed right now. Dont we live in a beautiful planet? 🐵🙈🙉🙊

So somebody forgot the cultures and 28 years later they turn it into an opportunity and a paper? 😇

In case you missed it: our review titled "Spatial structure: shaping the ecology and evolution of microbial communities" is out! 🚨

Let me hit you with some highlights on why spatial structure matters. (and why you should care!)

Sharing is appreciated 🙏 🧵👇

doi.org/10.1093/fems...

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Phage-microbe interactions may contribute to the population structure and dynamics of hydrothermal vent symbionts Abstract. Deep-sea hydrothermal vent ecosystems are sustained by chemoautotrophic bacteria that symbiotically provide organic matter to their animal hosts

Excited to share that @michelle-hauer.bsky.social's paper with @katiekliermicrobe.bsky.social @maggielangwig.bsky.social @karthik-a.bsky.social on phage interactions with chemosynthetic symbionts was published today. #NSF and @schmidtocean.bsky.social supported. academic.oup.com/ismecommun/a...

Differential Contributions From Chemo‐ and Photoautotrophy to Winter Primary Production in a North Temperate Freshwater System Changing winter conditions influence snow and ice accumulation in inland waterbodies Diverse communities of primary producers are responsible for the fixation of inorganic carbon year-round Guil...

Love this new paper from @tjvmajors.bsky.social and colleagues - looking at contributions of chemosynthetic contributions to net primary productivity with a focus on interesting winter dynamics! agupubs.onlinelibrary.wiley.com/doi/10.1029/...

There is no hierarchy, I repeat, there is no hierarchy.

No animal alive today is ‘primitive’ – why are so many still labeled that way? All species alive today, from chimpanzees to bacteria, are cousins that each have equally long lineages, rather than ancestors or descendants of one another.

The idea that humans sit atop an evolutionary hierarchy dates back to 1866, when a scientist drew the first tree of life with "Man" at the top. This inaccurate view still shapes how we think of the animal world, despite decades of genomic evidence proving evolution has no hierarchy.

buff.ly/055hdSo

Oxygen metabolism in descendants of the archaeal-eukaryotic ancestor - Nature Sequencing of marine sediments finds 136 newly identified Heimdallarchaeia and several novel lineages, and indicates that Heimdallarchaeia evolved distinct metabolic capabilities from other Asgardarchaeota, in conditions that may have given rise to early eukaryotes.

Nature research paper: Oxygen metabolism in descendants of the archaeal-eukaryotic ancestor

go.nature.com/4rSfRRw

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Photo of three Cladonia podetia that look like a bouquet of red flowers.

A bouquet of Cladonia #lichen.
#Newfoundland, Canada
#fungi #fungifriends
The lichens are approx 3cm high.

It's the small things in life... Alder Goblets (Ciboria caucus), a tiny cup fungus that appears this time of year on very wet fallen alder catkins. #fungifriends #mycology #naturephotography #fungiphotography

Personally, Im a fan of Frau Hesse. The number of discoveries her agar has made possible are incalculable. Well, actually calculable if people would give her credit …

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Photo of a sketch on a green cloth with 5 pens around it. The sketch depicts a green forest with, in the middle, a little tree and a little house. Somewhere are a samurai and a cat. Indian ink and technical pens on a4 paper.

Daily sketch 🏚🪾🥷🐈‍⬛️

Can you spot the cat ? What about the samurai ?

Below is a zoomed version of it :)

#art #artsky #ink #sketch

So what you really need is a snorkel!!!

Im in the good jacket AND umbrella camp. But I live in Humboldt so the precipitation regime is quite something else. ☔️🌧️🧥

Alright friends, I've been tasked with making Women in Science stickers for an event and I'm trying to expand both the racial and national diversity of the women who appear. So drop me your favorite women in science (loosely defined here) and, if possible, a symbol you'd use to exemplify their work

❤️❤️❤️

We don't have to choose between the economy and the planet.
The UN reports that nature-based solutions (restoring forests, sustainable agriculture) can provide 37% of the climate mitigation needed by 2030.
Investing in green jobs isn't charity,it’s the most intelligent long-term investment.

🚨important announcement🚨

Especially in your poo, you are cool too

😳🫣😵‍💫

Thread of available #sciart paintings at artologica.etsy.com

I want!

Oh to be a little Tardigrade walking around a microscopic volvox algae colony. 🫧🐻🧪

If somewhere, everywhere, and nowhere are words, then somewhen, everywhen, and nowhen also get to be words.

Insanely weird white bugs that look kind of like they've been created with a piping bag.

Hey, check out some cotton cushion scale bugs!