bioRxiv Genomics

Imputed transcriptional patterns in ancient genomes reveal molecular targets of selection https://www.biorxiv.org/content/10.1101/2025.11.21.689732v1

A chromosome-level genome assembly of the South African indigenous, Kolbroek pig, Sus scrofa domesticus https://www.biorxiv.org/content/10.1101/2025.11.20.689645v1

Reconstructing the network of horizontal gene exchange in bacteria to differentiate direct and indirect transfers https://www.biorxiv.org/content/10.1101/2025.11.20.689518v1

Dynamic Epigenetic Changes During Antidepressant Pharmacotherapy in Major Depressive Disorder https://www.biorxiv.org/content/10.1101/2025.11.20.688229v1

Widespread loss of Y expression in the absence of transcriptional dosage compensation in Rumex hastatulus https://www.biorxiv.org/content/10.1101/2025.11.20.689509v1

Dissecting sequence determinants of DNA methylation and in silico perturbation https://www.biorxiv.org/content/10.1101/2025.11.20.689274v1

Hidden in Plain Sight. How Ks histogram dynamics can reveal and obscure ancient whole genome duplications. https://www.biorxiv.org/content/10.1101/2025.11.19.689290v1

Integrating morphology and gene expression of neural cells in unpaired single-cell data using GeoAdvAE https://www.biorxiv.org/content/10.1101/2025.11.19.689368v1

A simple library preparation modification significantly reduces barcode crosstalk in ONT multiplexed sequencing https://www.biorxiv.org/content/10.1101/2025.11.19.689316v1

A Near Telomere-to-Telomere Reference Genome for Drakensberger Cattle Achieved Through Trio-Binned Long-Read Sequencing https://www.biorxiv.org/content/10.1101/2025.11.19.689200v1

From deserts to forests: sequencing of the giant forest hog completes the genomic history of the African Suids https://www.biorxiv.org/content/10.1101/2025.11.19.689022v1

Single-nucleotide resolution mapping of m6A of zebrafish mRNAs in early embryonic development links m6A modifications to the maternal-to-zygotic transition https://www.biorxiv.org/content/10.1101/2025.11.19.688951v1

Epigenomic and transcriptomic germ-free ageing atlas reveals sterile inflammation as an intrinsic ageing feature https://www.biorxiv.org/content/10.1101/2025.11.19.689100v1

De novo assembly of complete Plasmodium falciparum isolate genomes using PacBio HiFi sequencing technology https://www.biorxiv.org/content/10.1101/2025.11.19.689036v1

Widespread low-affinity motifs enhance chromatin accessibility and regulatory potential in mESCs https://www.biorxiv.org/content/10.1101/2025.11.18.685822v1

A deep learning framework for building INDEL mutation rate maps https://www.biorxiv.org/content/10.1101/2025.11.18.689146v1

Pan-cancer analysis reveals mtDNA copy number as a key determinant of mutational load and disease progression in cancer https://www.biorxiv.org/content/10.1101/2025.11.18.689019v1

PETRA: Prime editing of transcribed regulatory elements to assay expression https://www.biorxiv.org/content/10.1101/2025.11.18.689114v1

The 9p21.3 Coronary Artery Disease Risk Locus Modulates Vascular Cell-State Transitions via Enhancer-Driven Regulation of MTAP https://www.biorxiv.org/content/10.1101/2025.11.18.689066v1

Uncovering the genetic basis of fruit volatiles in Fragaria vesca through GWAS reveals FvJMT2 as a methyl benzoate biosynthesis gene with insect-repellent function https://www.biorxiv.org/content/10.1101/2025.11.18.689018v1

Neighboring codon adjacent nucleotides have a conserved influence on mRNA decay https://www.biorxiv.org/content/10.1101/2025.11.17.688958v1

Comparative genomic analyses shed light on the introduction routes of rice-pathogenic Burkholderia gladioli strains into Bangladesh https://www.biorxiv.org/content/10.1101/2025.11.17.688954v1

Frequent Whole-Genome Duplication Events Drive the Genomic Evolution of Triple-Negative Breast Cancer During Neoadjuvant Chemotherapy https://www.biorxiv.org/content/10.1101/2025.11.17.688693v1

Understanding epigenetic regulation in non-model plants: Transcriptomic responses to seed demethylation in leaves and roots of the annual herb Erodium cicutarium (Geraniaceae) https://www.biorxiv.org/content/10.1101/2025.11.17.688907v1

DNA methylation landscapes in human cells and their chromatin determinants https://www.biorxiv.org/content/10.1101/2025.11.17.688913v1

10,239 whole genomes with multiomic and clinical health information as the Korean population multiomic reference dataset https://www.biorxiv.org/content/10.1101/2025.11.17.688763v1

Telomere-to-Telomere Accurate and Gapless Korean Standard Reference Genome https://www.biorxiv.org/content/10.1101/2025.11.17.688257v1

Unraveling Genomic Signatures of lncRNA Expression in Zebrafish Caudal Fin Regeneration: Bridging Regenerative Potential and Positional Memory. https://www.biorxiv.org/content/10.1101/2025.11.17.688827v1

New genomic resources for an invasive mite pest help guide the development of KASP markers for pesticide resistance screening https://www.biorxiv.org/content/10.1101/2025.11.17.688773v1

Genomic Evidence for a Novel Introduction and Intra-host Diversity of DENV-2 in Dar es Salaam, Tanzania https://www.biorxiv.org/content/10.1101/2025.11.17.688789v1