Elaine Emmerson

Great to see #ECRs chairing sessions at @britsocimm.bsky.social #BSI25! Here’s our postdoc @lizihegarty.bsky.social excellently co-chairing the #neuroimmunology session alongside Jessica Teeling.

Tissue resident colonic macrophages persist through acute inflammation and adapt to aid tissue repair in this work from @lizihegarty.bsky.social, @bainlab.bsky.social, and colleagues: www.mucosalimmunology.org/article/S193...

Tripotent Lgr5 stem cells in the posterior tongue generate lingual, taste, and salivary gland lineages - Nature Communications Here, the authors show that a single Lgr5 stem cell population in the posterior tongue produces taste buds, salivary glands, and epithelium, representing unified chemosensory units.

A common LGR5+ cell gives rise to the #tongue epithelium, the #tastebuds and the von Ebner #salivaryglands. A lovely study from @hansclevers.bsky.social and colleagues.

www.nature.com/articles/s41...

If you work with #scRNAseq, #salivary, #thyroid or #mammary gland #organoids, or are interested in #irradiation and #Notch signaling, you might find this exciting! Our latest paper is now available in @embojournal.org! Check it out! Link below ✨

doi.org/10.1038/s443...

IFN-I signaling enhances salivary gland stem and progenitor cell activity after irradiation Regenerative responses in salivary gland organoids after irradiation are mediated by IFN-I signaling.

Extremely excited to see this out in @science.org Signaling! In this study, we explored the molecular differences between #photon and #proton irradiation and uncovered how #salivary gland stem cells respond to the resulting #inflammatory cues.

www.science.org/doi/10.1126/...

Intestinal blood vessel-associated macrophages and gut-vascular barrier dysfunction in cirrhosis Background Bacterial translocation in cirrhosis can trigger infection and hepatic decompensation, leading to systemic inflammation, organ failure and increased mortality. These infections often origin...

Delighted to share this! We identify gut #macrophages as key players in preventing dissemination of intestinal microbes in liver cirrhosis. Best collab with my partner in crime @lenasmets.bsky.social, featuring some stunning live imaging with @colindascheele.bsky.social
👇
gut.bmj.com/content/earl...

Tissue resident colonic macrophages persist through acute inflammation and adapt to aid tissue repair Macrophages are crucial for the maintenance of intestinal homeostasis, are considered key proinflammatory effector cells during intestinal inflammatio…

Thrilled for our wonderful postdoc @lizihegarty.bsky.social whose #PhD work on colonic #macrophages and #colitis with @bainlab.bsky.social @edinuni-irr.bsky.social has been accepted for publication in @mucosalimmunol.bsky.social 🔬

www.sciencedirect.com/science/arti...

Conserved signals control self-organization and symmetry breaking of murine bilayered epithelia during development and regeneration Journot et al. explore fate specification during embryonic development and regeneration of bilayered glandular epithelia. They uncover conserved molecular mechanisms linking tissue architecture with c...

A beautiful study describing cell fate acquisition in bilayered #epithelia, inc. my fave #salivarygland, published in @cp-devcell.bsky.social

Conserved signals control self-organization & symmetry breaking of murine bilayered epithelia during development & regeneration

www.cell.com/developmenta...

CCR2-driven monocyte recruitment is protective against radiotherapy-induced intestinal toxicity Radiotherapy (RT) is essential in treating abdominal and pelvic cancers but often damages the healthy tissues, particularly the intestines, leading to…

Wonderful to see this lovely data out in @mucosalimmunol.bsky.social! Congratulations to @nabinapun.bsky.social, @douglaspdyer.bsky.social & colleagues of @lydiabeckeriii.bsky.social & @mcrcellmatrix.bsky.social! 👏
#monocyte #radiotherapy #intestinal #toxicity
www.sciencedirect.com/science/arti...

A young man standing in front of Old College, Edinburgh University.

A young man standing next to a banner with the words “Advocating for parents and carers in STEMM” written on it.

Nice to spend the morning in the magnificent Playfair Library at @edinburgh-uni.bsky.social discussing how to better support #carers in #STEMM, organised by @carersinstemm.bsky.social, and with my very own dependent alongside me as it’s half term!

Frontiers | Salivary gland macrophages in health and disease: heterogeneity, niche crosstalk, and therapeutic avenues Salivary glands (SGs) produce saliva essential for digestion, mucosal immunity, and as a source of non-invasive biomarkers. The health and pathology of SGs h...

📖 A very comprehensive review of the heterogeneity, crosstalk and therapeutic potential of #salivarygland #macrophages including reference to several papers from @emmersonlab-irr.bsky.social
📚 #immunosky
www.frontiersin.org/journals/imm...

Sensory neurons shape local macrophage identity via TGF-β signaling Specialized macrophages are known to persist within tissue niches, but the molecular mechanisms guiding their sustained functional adaptation remain unclear. Kolter and Döring et al. show that local i...

TGFb mediates #macrophage specialisation and crosstalk with sensory #nerves in the #skin after injury. A beautiful study by Julia Kolter, Philipp Henneke and colleagues published in @cp-immunity.bsky.social #immunosky

www.cell.com/immunity/ful...

John Gurdon John Gurdon is at the Wellcome Trust/Cancer Research UK Institute of Cancer and Developmental Biology in Cambridge. Educated at Eton and Christ Church, Oxford, he changed from classics to zoology. Dur...

“For Gurdon to continue in biology would be a complete waste of time both for him and for those who would have to teach him”

He proved them wrong! RIP John Gurdon

www.cell.com/current-biol...

Great to see this out for all to see after a lot of hard work by @lizihegarty.bsky.social and @bainlab.bsky.social. Colonic #macrophages persist but are transcriptionally altered post- #inflammation in a mouse model of #colitis.

Absolutely delighted that our superstar #postdoc @lizihegarty.bsky.social was awarded the @cmvm-edinburghuni.bsky.social Student Support & Supervision Award for #PAW 2025. Thoroughly deserved for everything she does for @emmersonlab-irr.bsky.social, @bainlab.bsky.social & @edinuni-irr.bsky.social

A cracking meal complete with piper & Ceilidh to round off the second day of #EMDS2025 in #Edinburgh

#EMDS2025 attendees - if anyone is looking for a postdoc position and likes what they see of #Edinburgh, please come and speak to me or @lizihegarty.bsky.social (poster 71) or @erinwatson.bsky.social (poster 35).

After a year of planning, we are ready.

Registration opens at 8am. Excited for 2.5days of great science and a bit of fun.

See you soon

For anyone wanting to know more about this #postdoc position, I’ll be at @emds2025.bsky.social this week. Alternatively, you’ll find @emmersonlab-irr.bsky.social members @lizihegarty.bsky.social & @erinwatson.bsky.social at posters 71 & 35 #academicjobs

I am advertising for a #postdoc for a 3 year BBSRC-funded project exploring the role of macrophages in salivary gland development. The successful candidate will be based at @edinuni-irr.bsky.social at @uni-of-edinburgh.bsky.social. Closing date: 9th Oct. elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

Official advert coming soon! #postdoc #macrophages @britsocimm.bsky.social @emds2025.bsky.social
@edinuni-irr.bsky.social

Lovely @emmersonlab-irr.bsky.social outing with @lizihegarty.bsky.social and & @erinwatson.bsky.social to celebrate @abelsoto.bsky.social joining the lab for the summer and welcome incoming PhD student Natalie

I'll soon be advertising for a 3 year postdoc to join our lab at @edinuni-irr.bsky.social exploring #macrophages in salivary gland #development. Candidates should have a strong background in immunology/macrophage biology and/or developmental biology & key skills as below. Informal enquiries welcome!

Congratulations Naomi and team, lovely work!

👩🏻‍🔬👨🏼‍🔬 John McKendrick, Sonia Elder, Cecilia Rocchi, @erinwatson.bsky.social, @lizihegarty.bsky.social
👨🏻‍🎓🧑🏽‍🎓 @bainlab.bsky.social, Rebecca Gentek, Asier Unciti-Broceta, Anthony Callanan, Burkhard Becher
🏠 @edinuni-irr.bsky.social
And a special thank you to @swimberly.bsky.social for being my champion 💪🏻

I am extremely honoured to say that I have been named as the @iadr.bsky.social Salivary Researcher of the Year 2025 🏆 This is testament to my incredible team & wonderful collaborators over the last 8 yrs & my superb postdoc training at @ucsanfrancisco.bsky.social #salivarygland #salivary #research

As a postdoc I found that mimicking #nerve signals could help cell replenishment in #salivarygland. When I joined @edinuni-irr.bsky.social we teamed up with the incredible Unciti-Broceta lab from @uoe-igc.bsky.social to explore a novel #drugdelivery system: 📖 ➡️ www.researchsquare.com/article/rs-6...

A beautiful study out now in @cp-devcell.bsky.social showing that tissue architecture drives cell fate in branched #epithelial organs during #development.

Well done to @erinwatson.bsky.social for writing this wonderful review of what is known about macrophage crosstalk with peripheral nerves in a whole range of different tissues! @edinuni-irr.bsky.social #macrophage #nerve #neuroimmunology #immunosky

Doctor concern over fall in young people taking anti-cancer jab The HPV vaccine programme, which started in 2008, has been hugely successful across Scotland.

Building confidence in the #HPV #vaccine is so important to protect young people going forward. Massive 👏🏻 to our very own Dom Cairns-Gibson for leading the discussions with local Castlebrae students #vaccination @edinuni-irr.bsky.social @tcf-foundation.bsky.social
www.bbc.com/news/article...