Luke Green

Simple Sequence Repeats Mediate Phase Variation of the Mucoid Phenotype in Hypervirulent Klebsiella pneumoniae Hypervirulent Klebsiella pneumoniae (HVKp) express a thick mucoid capsular polysaccharide which is essential for virulence and survival in the bloodstream but inhibits epithelial adhesion and invasion...

🎉 Delighted to share the first pre-print from my lab where we demonstrate that intergenic DNA repeats mediate phase variation of the mucoid phenotype in hypervirulent Klebsiella pneumoniae: www.biorxiv.org/content/10.1... #klebclub

15.09.2025 09:51 — 👍 14    🔁 11    💬 1    📌 1

Well done to Anisha, Luisa and Paige for delivering fantastic talks at the IPNC in Florence.

03.04.2025 14:34 — 👍 5    🔁 2    💬 0    📌 0

Here we go!

30.03.2025 15:15 — 👍 1    🔁 0    💬 0    📌 0

At the pathogenic Neisseria conference in Florence with @neisseriaspanin.bsky.social

30.03.2025 12:09 — 👍 6    🔁 1    💬 1    📌 0

Addressing AMR requires a flexible OH approach that adapts to local contexts. In LMICs, this involves tackling challenges like sanitation and overcrowding, while in high-income countries, the OH model must also integrate environmental factors within healthcare systems.
www.bmj.com/content/386/...

13.01.2025 11:26 — 👍 20    🔁 9    💬 1    📌 0

Quickly followed with a picture of our dog....

22.12.2024 13:41 — 👍 6    🔁 0    💬 0    📌 0

Dynamics of the CD9 interactome during bacterial infection of epithelial cells by proximity labelling proteomics Epithelial colonisation is often a critical first step in bacterial pathogenesis, however, different bacterial species utilise several different receptors at the cell membrane to adhere to cells. We h...

This seems an interesting space....May as well start with a plug of our latest preprint! Amazing hard work from all in our lab. Thanks to Paige, Isabel, Mark and @jonshaw16.bsky.social for all their incredible input. Have a read, ask questions that make my brain hurt! www.biorxiv.org/content/10.1...

22.12.2024 13:40 — 👍 4    🔁 2    💬 0    📌 0