Arnaud Kengmo Tchoupa

Excited for this new preprint from former postdoc @caitlinkowa.bsky.social identifying unexpected functions for the bacterial stringent response in antimicrobial fatty acid susceptibility in S. aureus #microsky

Excited to announce the upcoming 2026 Microbial Toxins and Pathogenicity GRC and GRS meeting taking place July 12 - 17, 2026 at Waterville Valley in New Hampshire. This meeting will be chaired by yours truly and co-chaired by
@sunnyshinlab.bsky.social www.grc.org/microbial-to...

The @dmf-unil.bsky.social is supporting the application of a candidate for the SNSF/ERC Starting Grant (deadline 5th of May). Reach out to me if you are interested. We are collecting CV’s until the 8th of Feb. We can offer a stimulating scientific environment and help with the application/interview.

Fabian was quicker :) But yes, we have an open postdoc position in bacterial bioenergetics and membrane biology, using on B. subtilis as the model. Come join us! @cbcb-newcastle.bsky.social is a great place to work, and we are a friendly, international lab. Visa+IHS fees covered. #microsky

The staphylococcal type VII secretion system protein EsxC impacts daptomycin sensitivity through controlling bacterial cell envelope integrity | Journal of Bacteriology Type VII secretion system (T7SS) has a range of functions in bacteria, including specific roles in bacterial physiology, including DNA uptake, membrane integrity, and bacterial development. In S. aure...

Final paper from my postdoc with @meeraunnikri.bsky.social. Happy me!
journals.asm.org/doi/10.1128/...

I am delighted to announce that in January 2026 I will be starting a new permanent position @uniofgalway.bsky.social as a Lecturer/Assistant Professor in Microbiology!

#ZedenLab #Microbiology #AMR #Academia #Tenured #CareerMilestone #NewJob #Galway

We are hiring a postdoctoral researcher in our team at the @unistra @ibmc.bsky.social - 3 year ANR project in collaboration with the @dumenillab.bsky.social at @pasteur.fr focused on the survival of pathogenic bacteria upon plasma exposure
Apply here :
emploi.cnrs.fr/Gestion/Offr...

Postdoctoral Research Scientist - Newark, New Jersey (US) job with Dr Tania Wong | 12848863 Rutgers is currently seeking a Postdoc Research Scientist to join the Center for Immunity and Inflammation (CII) at the New Jersey Medical School.

🚀 We’re hiring a Postdoc!
Seeking expertise in spatial metabolite imaging and/or mass spectrometry to study how host metabolism shapes immune responses. If you're creative, collegial, and excited to push boundaries, we’d love to hear from you. Please share!

🔗 www.nature.com/naturecareer...

Proteoglycofili are glycosaminoglycan-containing fibrillar components released by neutrophils to neutralize bacteria Alternative to the formation of NETs, André et al. describe here that viable neutrophils may release a fibrillar component named proteoglycofili or PGF upon stimulation. PGF formation is associated wi...

Thrilled to share that neutrophils produce extra long fibrillar components named proteoglycofili or PGF. PGF are released by living neutrophils and do not contain DNA. They might look like NETs but are not NETs…

www.cell.com/cell-reports...

Description Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

We're advertising for a bacteriology technician and a post-doc to work on AI-guided antibiotic development as part of a large multidisciplinary Fleming Initiative project:
www.imperial.ac.uk/jobs/search-...

www.imperial.ac.uk/jobs/search-...

Now properly published at @natcomms.nature.com with few additional experiments incl. demonstration of Daptomycin's ability to depolarise non-growing cells.
See the original preprint-thread for a summary of our findings.
www.nature.com/articles/s41...
#microsky

Inhibition of fusidic acid resistance through restricting conformational flexibility in domain III of EF-G | PNAS Fusidic acid (FA) is one of few remaining antibiotics active against Methicillin-resistant Staphylococcus aureus. FusB confers resistance to FA by ...

Happy to see work I contributed to during my MSc at @bioscienceleeds.bsky.social with Jennifer Tomlinson’s lab out in @pnas.org! Everyone Bluesky-less except @antoncalabrese.bsky.social

www.pnas.org/doi/10.1073/...

#AMR #MRSA #NMR

Competitive fitness of Staphylococcus aureus against nasal commensals depends on biotin biosynthesis and acquisition Abstract. The human nasal microbiome can serve as a reservoir for pathogens. In particular, the opportunistic pathogen Staphylococcus aureus can be a membe

Really happy to see the final version of this published in @isme-microbes.bsky.social. We show that production of and competition for biotin shapes S. aureus fitness in the context of nasal commensals doi.org/10.1093/isme...
Work lead by the amazing Kevser Bilici!

EASTBIO How do transporters promote the fitness of Staphylococcus aureus in different host-species ? at University of Edinburgh on FindAPhD.com PhD Project - EASTBIO How do transporters promote the fitness of Staphylococcus aureus in different host-species ? at University of Edinburgh, listed on FindAPhD.com

PhD position on bacterial (Staph aureus) transporters and host-adaptation in my group @roslininstitute.bsky.social @edinburgh-uni.bsky.social

www.findaphd.com/phds/project...

Molecular dissection of Staphylococcus aureus in Atopic Dermatitis Using a Human Skin Organoid model at University of Edinburgh on FindAPhD.com PhD Project - Molecular dissection of Staphylococcus aureus in Atopic Dermatitis Using a Human Skin Organoid model at University of Edinburgh, listed on FindAPhD.com

PhD fellowship position in my group @roslininstitute.bsky.social
@edinburgh-uni.bsky.social on Staph aureus host-pathogen interactions in atopic dermatitis using human skin organoids in collaboration with the brilliant Sara Brown.
www.findaphd.com/phds/project...

Fluorescein-based dyes are not valid reporters of oxidative stress in bacteria, and conclusions based on their use must be reconsidered | PNAS Dihydrodichlorofluorescein derivatives have been employed as reporters of intracellular reactive oxygen species (ROS) in innumerable studies. Their...

Hmmm
This work has so many implications on literature 😳😬

Fluorescein-based dyes are not valid reporters of oxidative stress in bacteria, and conclusions based on their use must be reconsidered | PNAS www.pnas.org/doi/10.1073/...

Let me use this as an opportunity to talk about Jordi et al's very cool paper, now out in PNAS 🧪:

pmc.ncbi.nlm.nih.gov/articles/PMC...

You can read our news and views here: www.pnas.org/doi/10.1073/...

📣New preprint alert! We report the alarming finding that stringent response mutations found in clinical isolates increase the frequency of donation of multiresistance plasmids in S. aureus 😱 Great team effort @microclaire.bsky.social @paulrjohnston.bsky.social

www.biorxiv.org/content/10.1...

📢 Postdoc position: Biochemistry & Bacterial cell biology

in our group at Marburg University, Germany, funded by the ERC Advanced Grant "C-SWITCH"

🔗More information at shorturl.at/OlvlL
📅Deadline: Nov 30, 2025

Please repost. #Postdoc

Exciting Opportunity: Biomolecular Science Fellowship Day The School of Biology at the University of St Andrews is inviting applications from outstanding visionary Research Fellow and Future Leader candidates to attend the Biomolecular Science (BMS) Fello…

📣 Calling all senior microbiology postdocs! The University of St Andrews is inviting applications from outstanding visionary Research Fellow and Future Leader candidates to attend a Biomolecular Science Fellowship Day. Applications due by 12th Dec, see link for full details: tinyurl.com/4n3na8vn

📢 Postdoc position: Cell Biology of Cyanobacteria

in my group, as part of the Excellence Cluster "Microbes for Climate" (M4C) in Marburg, Germany.

More information at shorturl.at/wNnDT (see Project 2)

🔗Apply at shorturl.at/VsEDl
📅Deadline: Nov 16, 2025

Please repost. #Postdoc

MRC DiMeN Doctoral Training Partnership: Resensitisation of antibiotic-tolerant Staphylococcus aureus small colony variants at Newcastle University on FindAPhD.com PhD Project - MRC DiMeN Doctoral Training Partnership: Resensitisation of antibiotic-tolerant Staphylococcus aureus small colony variants at Newcastle University, listed on FindAPhD.com

Looking for an AMR-themed PhD project? Join us to investigate antibiotic tolerance in Staphylococcus aureus through a fully funded MRC DTP PhD studentship starting in September 2026.

This project is close collaboration with @kateduncan.bsky.social and @mycobacterium-ncl.bsky.social.

Please RT. Post-doc opportunity alert! 💥 closing 10th December.. Come join our team (www.thelowlab.org) at Imperial, London, working on the structure and mechanism of bacterial secretion systems.

For more details and to apply please see

www.imperial.ac.uk/jobs/search-...

Isolation, engineering and ecology of temperate phages from the human gut - Nature Human host-associated cellular products may act as induction agents for bacteriophages.

Very excited to share the latest work from our lab, which was published today in Nature!
nature.com/articles/s41...

PhD graduate and now post-doc Sofia Dahlman, along with co-senior author Sam Forster from The Hudson and other researchers from our lab and others.

New review - thanks to Markus Weingarth for the invitation! www.nature.com/articles/s41...

E15 Groups The Helmholtz Institute for RNA-based Infection Researchopens a call for

Looking to start your own lab? 🧬🧪 The Helmholtz Institute Würzburg (HIRI) is offering group leader positions in RNA biology, RNA medicine & RNA technology. Apply by October 31 at www.helmholtz-hiri.de/en/jobs-tale...

Strain-resolved CRISPRi-Seq reveals conserved antibiotic vulnerabilities in Staphylococcus aureus https://www.biorxiv.org/content/10.1101/2025.10.13.682098v1

A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics - Nature Microbiology The authors developed a screen to find compounds that modulate intracellular Staphylococcus aureus metabolism and discovered KL1, which sensitizes persisters to antibiotics by reversing host-induced tolerance.

Delighted to share our latest paper - A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics. Excellently led by Dr. Kuan-Yi Lu. We think it's a great proof-of-concept that altering immune cell behavior can make antibiotics work better www.nature.com/articles/s41...

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.

Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.

Apply now ➡️ www.crick.ac.uk/careers-stud...

Pre- and postantibiotic epoch: The historical spread of antimicrobial resistance Plasmids are now the primary vectors of antimicrobial resistance, but our understanding of how human industrialisation of antibiotics influenced their evolution is limited by a paucity of data predati...

Imagine we could travel back in time ⏪⌛️to explore the world of bacterial pathogens before humans discovered and industrialised antibiotics

We just did that to study the history of #AMR spread @science.org
doi.org/10.1126/scie...

If you like time travel & biology, this 🧵is for you👇