IntFOLD

Highlights of Model Quality Assessment in CASP16 Model quality assessment (MQA) remains a critical component of structural bioinformatics for both structure predictors and experimentalists seeking to use predictions for downstream applications. In ...

Our paper on the performance of ModFOLDdock2 at #CASP16 onlinelibrary.wiley.com/doi/10.1002/...

05.09.2025 08:41 — 👍 1    🔁 1    💬 0    📌 0

Inter-platelet communication driving thrombus formation is regulated by extracellular calpain-1 cleavage of connexin 62 | Haematologica

We used IntFOLD, and MultiFOLD to model interactions between Cx62 and calpain-1: "Inter-platelet communication driving thrombus formation is regulated by extracellular calpain-1 cleavage of connexin 62" | Haematologica haematologica.org/article/view...

05.08.2025 08:41 — 👍 1    🔁 1    💬 0    📌 0

Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers Abstract. Understanding the structures of protein complexes is pivotal for breakthroughs in health, agriculture, bioengineering, and beyond. MultiFOLD2 and

Our new paper has been published: Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers url: academic.oup.com/nar/article/...

09.07.2025 08:36 — 👍 3    🔁 1    💬 0    📌 0

Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers Abstract. Understanding the structures of protein complexes is pivotal for breakthroughs in health, agriculture, bioengineering, and beyond. MultiFOLD2 and

Our new paper is out: Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers
academic.oup.com/nar/advance-...

28.04.2025 08:54 — 👍 2    🔁 2    💬 0    📌 0

Inter-platelet communication driving thrombus formation is regulated by extracellular calpain-1 cleavage of connexin 62 - PubMed Connexin (Cx) gap junction proteins are expressed by a multitude of cells and function as plasma membrane hemichannels or dock to form intercellular communication tunnels. Whilst Cx43 has garnered con...

Pleased to share that our latest study has been published in Hematologica!

@rdgplateletlabs.bsky.social

pubmed.ncbi.nlm.nih.gov/40045892/

07.03.2025 16:09 — 👍 11    🔁 5    💬 0    📌 0

Bioinformatics Web Servers - University of Reading

The main link for IntFOLD server:

reading.ac.uk/bioinf/IntFO...

18.02.2025 13:48 — 👍 0    🔁 0    💬 0    📌 0

Yesterday at #CASP16 I presented our new ModFOLDdock2 servers for the quality assessment of multimer models. It's great to see progress in the field but there are still many challenges ahead!

03.12.2024 13:43 — 👍 2    🔁 2    💬 0    📌 0

My group members, Shaima and @recep44.bsky.social, presented their posters on MultiFOLD2 for multimer modelling and FunFOLD5 for predicting protein-ligand interactions at #CASP16. Lots of interest and positive feedback!

03.12.2024 13:47 — 👍 7    🔁 3    💬 0    📌 0

ModFOLDdock2 is the top ranked method for predicting the interface accuracy of modelled protein complexes #CASP16. The server is available here: www.reading.ac.uk/bioinf/ModFO...

03.12.2024 15:37 — 👍 12    🔁 4    💬 1    📌 0

The ModFOLDdock2 server is now online and freely available to all. The ModFOLDdock2 variants ranked within the top few groups at #CASP16 in QMODE1/2 metrics. ModFOLDdock2 is the best method for predicting the interface accuracy of modelled protein complexes.
www.reading.ac.uk/bioinf/ModFO...

11.12.2024 16:01 — 👍 2    🔁 1    💬 1    📌 0

Our MultiFOLD2 server is also now freely available to all. It's the top-ranked server on the hardest domain targets in #CASP16 by GDT_TS. With integrated stoichiometry prediction it outperforms AF3 on common multimer subsets in CAMEO. www.reading.ac.uk/bioinf/Multi...

12.12.2024 16:55 — 👍 12    🔁 6    💬 1    📌 0