Brenton Graveley's Avatar

Brenton Graveley

@graveley.bsky.social

Scientist, Husband, Father, Potter, Athlete, bengal cat lover, Great Dane addict, dungeons and dragons fanatic. Hartford, CT Professor and Chair, Department of Genetics and Genome Sciences, Associate Director Institute for Systems Genomics, UConn Health

770 Followers  |  937 Following  |  96 Posts  |  Joined: 15.10.2023
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Posts by Brenton Graveley (@graveley.bsky.social)

Giant nope. I don’t have polite words for this guy especially as he treats children. I don’t care how “nice and caring” his wife says he is. That may be but his ideas are more than misguided and his proposal is unethical

26.01.2026 14:10 — 👍 4    🔁 4    💬 0    📌 0
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Had the opportunity to listen to Pete Buttigieg last night. Lent some sanity to an insane world

25.01.2026 13:30 — 👍 10    🔁 2    💬 1    📌 0
This line graph illustrates the percentage change in agency staff levels from the previous year for nine major U.S. federal scientific and health organizations between the fiscal years 2016 and 2025. The agencies tracked include the CDC, Department of Energy, EPA, FDA, NASA, NIH, NIST, NOAA, and NSF. For the majority of the timeline between 2016 and 2023, the agencies show relatively stable fluctuations, generally staying within a range of +5% to -5% change per year. However, there is a dramatic and uniform plummet starting in the 2024–25 period. Every agency depicted shows a sharp downward trajectory, with staffing losses ranging from approximately -15% to over -25%. The Environmental Protection Agency (EPA) shows the most significant decline, dropping to roughly -26%, while the National Institute of Standards and Technology (NIST) shows the least severe but still substantial drop at approximately -15%.

This line graph illustrates the percentage change in agency staff levels from the previous year for nine major U.S. federal scientific and health organizations between the fiscal years 2016 and 2025. The agencies tracked include the CDC, Department of Energy, EPA, FDA, NASA, NIH, NIST, NOAA, and NSF. For the majority of the timeline between 2016 and 2023, the agencies show relatively stable fluctuations, generally staying within a range of +5% to -5% change per year. However, there is a dramatic and uniform plummet starting in the 2024–25 period. Every agency depicted shows a sharp downward trajectory, with staffing losses ranging from approximately -15% to over -25%. The Environmental Protection Agency (EPA) shows the most significant decline, dropping to roughly -26%, while the National Institute of Standards and Technology (NIST) shows the least severe but still substantial drop at approximately -15%.

This is the most astonishing graph of what the Trump regime has done to US science. They have destroyed the federal science workforce across the board. The negative impacts on Americans will be felt for generations, and the US might never be the same again.

www.nature.com/immersive/d4...

20.01.2026 22:53 — 👍 14451    🔁 8318    💬 90    📌 765
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5-year-old boy among four students detained by ICE, according to school leaders School district leaders argue ICE agents are following students and their parents while driving to and from school.

This comes just after the president publicly demanded that ICE should start showing the public how terrible the people are who they're grabbing and arresting.

In this case, his name is Liam. He's five years old.

www.kare11.com/article/news...

22.01.2026 02:40 — 👍 4516    🔁 1974    💬 247    📌 109
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Progress and challenges in profiling protein-RNA and protein-associated RNA-RNA interactions - PubMed RNA binding proteins (RBPs) play essential roles in post-transcriptional gene regulation by interacting with a wide range of RNA targets. In addition to regulating RNA processing via individual RBP-RNA interactions, there is a growing appreciation of the regulatory impact of protein-associated RNA-R …

Happy to share Joey (Zhuoyi)'s review on technologies to map RBP:RNA and (especially) RBP-associated RNA:RNA interactions is now up at RNA! pubmed.ncbi.nlm.nih.gov/41535089

18.01.2026 03:29 — 👍 24    🔁 8    💬 1    📌 2
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24 members of Congress are 80 or older. More than half are running for re-election. While older members of leadership in the House and the Senate are retiring, some from the Silent Generation say their seniority is still a boon for their districts.

We need age limits...
24 members of Congress are 80 or older, and more than half are running for re-election. Thirteen of the 24 have decided to run again in 2026, according to an NBC News review.
www.nbcnews.com/politics/con...

17.01.2026 02:38 — 👍 288    🔁 142    💬 52    📌 13
A line grant showing non-competitive renewal awards made by NIH is fiscal year 2026 compared to 2021-2025. The line for fiscal year 2026 shows a lag due to the government shutdown in October and November and then follows the other curves but the lags due to the delay remains.

A line grant showing non-competitive renewal awards made by NIH is fiscal year 2026 compared to 2021-2025. The line for fiscal year 2026 shows a lag due to the government shutdown in October and November and then follows the other curves but the lags due to the delay remains.

Non-competitive renewal awards.

On a more or less normal curve but not catching up from the government shutdown-related delay.

All ICs except for NIAAA and NCCIH have made some awards with NIAID having made the most at 579.

2/2

16.01.2026 14:37 — 👍 20    🔁 13    💬 1    📌 0
A line grant showing new and competitive renewal awards made by NIH is fiscal year 2026 compared to 2021-2025. The line for fiscal year 2026 is very close to zero.

A line grant showing new and competitive renewal awards made by NIH is fiscal year 2026 compared to 2021-2025. The line for fiscal year 2026 is very close to zero.

My (now) weekly update on 2026 NIH funding.

New and competitive renewal awards.

3 new awards (compared to ~100 expected based on recent years).

No new ICs... still just NIA, NINDS, NIDCD, and NIDCR.

1/2

16.01.2026 14:37 — 👍 95    🔁 55    💬 9    📌 5
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In remembrance of Peer Bork  | EMBL EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.

very sad news. Peer Bork was one of the leaders of our field, a wonderful scientist, and he's much too young to be gone. www.embl.org/news/embl-an...

16.01.2026 18:33 — 👍 144    🔁 82    💬 10    📌 7
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When Everything Changes at Once: Making Sense of Institutional Overload NIH Office of Extramural Research is Implementing a Plan for “Administrative Burden Reduction”

Latest post from Dr. Ginexi on NOFO guidance, "reductions in burden," and subsequent confusion at #NIH.

14.01.2026 15:15 — 👍 25    🔁 15    💬 0    📌 2

Multi year funding will be a disaster and must not happen

14.01.2026 22:09 — 👍 1    🔁 0    💬 0    📌 0
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Genome-wide profiling of RNA 2'-O-methylation in neurons and identification of orphan snoRNA targets We have compared genome-wide patterns of RNA 2'-O-methylation (Nm) between two isogenic pairs of neurons. Each pair includes one line harboring a small deletion of orphan box C/D snoRNAs (SNORD116s) f...

Latest paper from the lab in collaboration with Gordon Carmichael, JD Beaudoin, and Chris Holley’s labs. www.biorxiv.org/content/10.6...

19.12.2025 03:16 — 👍 5    🔁 1    💬 0    📌 0

Zero chance Trump wins the peace prize tomorrow.

10.10.2025 02:23 — 👍 3    🔁 1    💬 0    📌 0

Wouldn’t even have to change dialog at all

10.10.2025 02:20 — 👍 2    🔁 0    💬 0    📌 0

The President of the United States just stood in front of top military leaders and declared that there’s a “domestic enemy” days after he said he was “authorizing full force” against an American city. This entire country should be outraged, not apathetic because it’s Trump.

30.09.2025 16:20 — 👍 311    🔁 95    💬 13    📌 0

I said what I said.

23.09.2025 02:34 — 👍 1644    🔁 356    💬 81    📌 30
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RFK Jr: “Research on vaccines and autism has been suppressed.”

PubMed: “Here’s over 1200 research papers on vaccines and autism…

…including this first one which is a meta-analysis showing that vaccines are not associated with autism.”

23.09.2025 01:58 — 👍 399    🔁 144    💬 18    📌 2

“The law doesn’t matter anymore” is obeying in advance.

19.09.2025 02:21 — 👍 6227    🔁 1503    💬 188    📌 37
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The union representing the musicians from Jimmy Kimmel’s band releases a statement calling the FCC’s pressure on Disney “state censorship.”

18.09.2025 01:59 — 👍 30069    🔁 10002    💬 611    📌 419

They are literally canceling culture

18.09.2025 00:26 — 👍 22528    🔁 4200    💬 412    📌 93
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RFK Jr.’s damage to the CDC is ‘past the point of no return,’ Dr. Demetre Daskalakis warns “The CDC you knew is over,” the infectious diseases doctor told The Advocate. “Unless someone takes radical action, there is nothing there that can be salvaged.”

there is no question in my mind that rfk jr is the most dangerous person in this administration and that his eugenicist ideology threatens the lives of millions of people www.advocate.com/politics/dem...

29.08.2025 20:53 — 👍 28126    🔁 8850    💬 478    📌 463
O’Neill, unlike Monarez, has no training in medicine or infectious disease science. He is a former speechwriter for the health department, during the Bush years, who went on to work for the tech investor and conservative megadonor Peter Thiel.

During the Covid pandemic, O’Neill voiced public support for unproven treatments that were not supported by scientific evidence, including ivermectin and hydroxychloroquine, as well as vitamin D as a supposed “prophylaxis”.

He also posted a number of conspiratorial theories on social media, including the baseless claim that “the name #COVID was chosen to conceal the origin of the virus. This name made it harder to study and probably slowed the response.”

O’Neill, unlike Monarez, has no training in medicine or infectious disease science. He is a former speechwriter for the health department, during the Bush years, who went on to work for the tech investor and conservative megadonor Peter Thiel. During the Covid pandemic, O’Neill voiced public support for unproven treatments that were not supported by scientific evidence, including ivermectin and hydroxychloroquine, as well as vitamin D as a supposed “prophylaxis”. He also posted a number of conspiratorial theories on social media, including the baseless claim that “the name #COVID was chosen to conceal the origin of the virus. This name made it harder to study and probably slowed the response.”

On the new acting CDC director. www.theguardian.com/us-news/2025...

29.08.2025 01:59 — 👍 1690    🔁 765    💬 83    📌 123
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Pay attention. Your family’s safety is on the line.

28.08.2025 22:47 — 👍 12351    🔁 4891    💬 456    📌 210

🧪That’s not how it works.

Science doesn’t care about your feelings.

So essentially if the people don’t like science we should ignore the potential it has.

In his op ed in the WaPo, JB has proven that he should not be taken seriously. He’s DEFINITELY not a real scientist.

13.08.2025 02:53 — 👍 102    🔁 29    💬 7    📌 1

If the Supreme Court rules for the Trump administration in this case, biomedical research is finished in this country.

13.08.2025 00:26 — 👍 128    🔁 59    💬 0    📌 2
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‘It’s a nightmare.’ U.S. funding cuts threaten academic science jobs at all levels “There is a lot of pressure to essentially leave the country or not pursue research,” one Ph.D. student says

I can't stress enough how close U.S. science is to the cliff.

"Numbers released in May by the National Science Foundation (NSF) indicate that if Congress approves the cuts to the agency proposed by the White House, the number of early-career researchers it supports could fall by 78%" (@science.org)

08.07.2025 15:36 — 👍 1463    🔁 839    💬 44    📌 72
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Franklin W. Stahl, 95, Dies; Helped Create a ‘Beautiful’ DNA Experiment

Franklin W. Stahl, 95, Dies; Helped Create a ‘Beautiful’ DNA Experiment. Gift article:
www.nytimes.com/2025/07/07/s...

09.07.2025 02:24 — 👍 62    🔁 12    💬 4    📌 2
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CNN chief data analyst Harry Enten:

“American people don’t see this as a big, beautiful bill. They see it as a big, bad bill. They hate it, hate it, hate it! They think it’s awful, awful, awful!”

30.06.2025 23:08 — 👍 5430    🔁 1594    💬 244    📌 86

Absolutely this 👇

10.06.2025 09:33 — 👍 84    🔁 21    💬 1    📌 0
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US science is being wrecked, and its leadership is fighting the last war Facing an extreme budget, the National Academies hosted an event that ignored it.

US science is being wrecked, and its leadership is fighting the last war arstechnica.com/science/2025...

05.06.2025 12:07 — 👍 134    🔁 51    💬 1    📌 8