Always exciting to see physical–organic sulfur chemistry in @ChemBioChem – isolable cysteine sulfenyl iodide in a “molecular cradle” as a hyper-electrophilic sulfenic-acid sibling and Cys–Trp gateway, reshaping ideas about halogen-mediated Cys oxidation.
🔗 doi.org/10.1002/cbic...
19.11.2025 14:06 — 👍 0 🔁 0 💬 0 📌 0
Always great to see rigorous mechanistic work in sulfur probe chemistry from @mdpluth.bsky.social.
This study clarifies that thiophene-ester probes respond to thiols & esterases—not H₂S—helping sharpen design principles across the redox probe field.
🔗 doi.org/10.1021/acsc...
12.11.2025 10:14 — 👍 1 🔁 0 💬 0 📌 0
A thoughtful contribution from the Xian Lab.
Phthalimide-based sulfur transfer reagents that install trisulfides on biothiols and proteins under mild, biologically relevant conditions.
doi.org/10.1039/d5ob...

10.11.2025 14:20 — 👍 1 🔁 0 💬 0 📌 0