A Naqvi's Avatar

A Naqvi

@anaqvi.bsky.social

New York ripened, Philly hardened. First gen. Principal Bfx Scientist (PhD) at @ChildrensPhila and http://d3b.center. Human rights. Cancer genomics. Tweets are my own. #openscience

635 Followers  |  288 Following  |  36 Posts  |  Joined: 24.09.2023
Posts Following

Posts by A Naqvi (@anaqvi.bsky.social)

Post image

For January, the editors of AACR’s 10 peer-reviewed journals highlighted studies about better understanding the naked mole rat’s cancer resistance, the importance of using tissue and liquid biopsy in concordance, and more Read on the #AACRBlog: buff.ly/vi2eP6h

02.02.2026 14:35 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 2
Preview
The Companies Behind ICE Sludge built an interactive map of every ICE contractor working with the Trump administration.

The Companies Behind Ice: Mapped

readsludge.com/2026/01/16/t...

02.02.2026 22:45 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1
Frest fruit and vegetables with hands forming a heart

Frest fruit and vegetables with hands forming a heart

We understand that the government shutdown is impacting vital support of SNAP and WIC effective 11/1 for our families and community members. Access to healthy food is crucial. If you need assistance, check out local resources here: ms.spr.ly/63328tEcIm.

31.10.2025 17:21 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
Preview
Why the next generation of mRNA vaccines is set to be even better

Scientists are designing mRNA vaccines to produce virus-like nanoparticles, which should lead to a more robust immune response with even fewer side effects than either of these immunisation approaches on their own

22.10.2025 03:26 β€” πŸ‘ 22    πŸ” 5    πŸ’¬ 0    πŸ“Œ 1

I try really hard to not gate keep data, but if you don’t understand basic formats and conversions, I’m sorry that is on you πŸ™ƒ

07.10.2025 14:33 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

New hope for kids with brain tumors! Read about the latest #CBTN breakthrough. https://monkeylink.co/628011 #BrainTumorResearch

19.08.2025 16:06 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Preview
What you need to know about mRNA vaccines in light of RFK's claims

The US health secretary is cutting funding for mRNA vaccines because he claims they are less effective than other types – but that is not what the evidence shows

11.08.2025 19:26 β€” πŸ‘ 8    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1
Preview
NRCAM variant defined by microexon skipping is a targetable cell surface proteoform in high-grade gliomas Aberrant splicing of microexons yields non-canonical surface receptors, such as the neuronal cell adhesion molecule (NRCAM) lacking amino acids encoded by exons 5 and 19. Sehgal et al. show that Ξ”ex5Ξ”...

Our paper is finally out there! And yes, we discovered the role of microexons in immunotherapy targeting in high-grade gliomas! www.cell.com/cell-reports...

08.08.2025 15:02 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Cancelling $500 million in vaccine research is exactly what a virus would do if it ran the Department of Health and Human Services.

06.08.2025 17:22 β€” πŸ‘ 1253    πŸ” 409    πŸ’¬ 72    πŸ“Œ 24

We'll have to do a "March for mRNA" πŸ€¦β€β™‚οΈ

06.08.2025 00:53 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1

Wow!!The normalization of Islamophobia across our society and institutions is everywhere, really unavoidable and on full display, as we start the process to elect NYC’s first Muslim mayor.

27.06.2025 12:34 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

let’s go!

12.06.2025 06:02 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Connor’s strength was eternal, and his love for life knew no bounds. He and #RCDFoundation show what true fortitude looks like. Connor had strengthβ€”now we honor it.
#ThisIsWhy #BrainTumorAwarenessMonth

23.05.2025 15:50 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Video thumbnail

CHOP & @pennmedicine.bsky.social have delivered the first-ever personalized gene editing therapy for a patient with CPS1 deficiency, marking a major milestone in the application of CRISPR-based treatments.

Learn more about KJ & the future of personalized medicine: www.chop.edu/news/worlds-....

15.05.2025 17:04 β€” πŸ‘ 99    πŸ” 18    πŸ’¬ 3    πŸ“Œ 14
Preview
How dark energy findings may inspire a new generation of physics nerds The discovery of the cosmic acceleration problem truly inspired me as a teenage physics nerd. Recent, related revelations about dark energy will hopefully capture the interest of today’s young science geeks, says Chanda Prescod-Weinstein

The discovery of the cosmic acceleration problem truly inspired me as a teenage physics nerd. Recent, related revelations about dark energy will hopefully capture the interest of today’s young science geeks, says Chanda Prescod-Weinstein

15.05.2025 18:58 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Preview
Science is a Pandora's box – but we should open it anyway We are often warned of the consequences of knowing too much, but even when scientific ideas have the potential to be harmful we should still seek to understand them

We are often warned of the consequences of knowing too much, but even when scientific ideas have the potential to be harmful we should still seek to understand them

11.05.2025 16:39 β€” πŸ‘ 9    πŸ” 3    πŸ’¬ 2    πŸ“Œ 1
Preview
Trump budget draft proposes NIH consolidation and 40% spending cut Draft Trump budget proposes a $20 billion NIH budget cut in 2026 and a sweeping consolidation

Draft Trump budget proposes a $20 billion NIH budget cut in 2026 and a sweeping consolidation

17.04.2025 02:45 β€” πŸ‘ 17    πŸ” 16    πŸ’¬ 0    πŸ“Œ 0
Preview
Beyond the Gene in Genetics: How Isoform-Resolved Analysis Empowers the Study of Both Common and Rare Genetic Variation Genetics is rapidly deepening our understanding of human health and disease by investigating common and rare genetic variants and their influence on gene expression1,2. Alternative splicing is a molec...

The Genetics research community has a problem. Most recent articles do not consider #splicing/isoforms.

Here, we analyze how important this opportunity gap is - and spoiler warning - we find it is essential for both analysis of common and rare variants

More infoπŸ‘‡

www.medrxiv.org/content/10.1...

02.04.2025 07:45 β€” πŸ‘ 29    πŸ” 10    πŸ’¬ 3    πŸ“Œ 0

It's not just COVID. mRNA vaccines tech is yielding incredible early results for treating cancer. We need more, not less science!

"...six out of eight who responded to the vaccine in the first study did not have their cancer return more than 3 years later"

www.sciencefriday.com/segments/pan...

17.03.2025 20:49 β€” πŸ‘ 45    πŸ” 12    πŸ’¬ 0    πŸ“Œ 2
Post image

Bsky vs Twitter engagement difference now 50-fold...

11.03.2025 16:18 β€” πŸ‘ 234    πŸ” 33    πŸ’¬ 6    πŸ“Œ 7
Preview
Trump 2.0: an assault on science anywhere is an assault on science everywhere US President Donald Trump is taking a wrecking ball to science and to international institutions. The global research community must take a stand against these attacks.

Inexplicably, US administration has launched an unprecedented assault on science, on research institutions & on vital international organizations & initiatives.

An assault on science anywhere is an assault on science everywhere; the global community must unite
πŸ§ͺ
www.nature.com/articles/d41...

25.02.2025 19:48 β€” πŸ‘ 366    πŸ” 196    πŸ’¬ 13    πŸ“Œ 15
Preview
Critics say Trump’s executive orders to reshape the NIH β€˜will kill’ Americans Executive orders’ impact on premier medical research agency has resulted in delayed projects and frozen funding

Guardian article on NIH

www.theguardian.com/us-news/2025...

22.02.2025 12:36 β€” πŸ‘ 84    πŸ” 44    πŸ’¬ 3    πŸ“Œ 5

Honest question: is something β€œreproducible” if it requires exorbitant amount of $$$ to reproduce (ie inaccessible)?

19.02.2025 15:30 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

umm… β€œβ€¦ filed provisional patents for the bioinformatics pipeline and the targets discovered in the paper”

13.02.2025 05:11 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image Post image Post image Post image

We did it! Go Birds πŸ¦…πŸ¦…πŸ¦…

10.02.2025 18:27 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
22 states sue to block Trump administration cuts to NIH research payments Attorneys general sued the Trump administration to block a NIH decision that would slash grant payments for research overhead

#BREAKING - 22 states sue to block Trump administration cuts to NIH research payments

10.02.2025 17:26 β€” πŸ‘ 128    πŸ” 55    πŸ’¬ 2    πŸ“Œ 6

Re-posting given recent adds
go.bsky.app/9asWtuD

15.12.2024 15:01 β€” πŸ‘ 72    πŸ” 16    πŸ’¬ 1    πŸ“Œ 2
Preview
Neuronal cell adhesion molecule (NRCAM) variant defined by microexon skipping is an essential, antigenically distinct, and targetable surface proteoform in high-grade glioma To overcome the paucity of known tumor-specific surface antigens in pediatric high-grade glioma (pHGG), we contrasted splicing patterns in pHGGs and normal brain samples. Among alternative splicing ev...

The preprint is finally out! Microexons to the rescue, and potentially targetable in deadly high-grade gliomas. www.biorxiv.org/content/10.1...

23.01.2025 21:37 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0