San Antonio Breast Cancer Symposium

#SABCS25 e-posters are available to meeting registrants for viewing through Tuesday, March 31. Learn more:
buff.ly/Z5orepv

#SABCS25 e-posters are available to meeting registrants for viewing through Tuesday, March 31. Learn more:
buff.ly/Z5orepv

#SABCS25 e-posters are available to meeting registrants for viewing through Tuesday, March 31. Learn more:
buff.ly/Z5orepv

#SABCS25 recap: Panelists examined the latest knowledge about the connections between breast cancer and lifestyle factors. Learn more in SABCS Meeting News:
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#SABCSSnippets: Marcela Mazo talked with Marjolein Smidt at #SABCS25 about the results of the Phase III BOOG 2013-08 trial, which indicate that sentinel lymph node biopsy may be safely omitted in some patients with early-stage breast cancer.
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#SABCSSnippets: Saba Shaikh talked with Sonia Pernas at #SABCS25 about the Phase II SUMIT-BC trial, which showed that the CDK7 inhibitor samuraciclib + fulvestrant showed efficacy in HR+ metastatic breast cancer patients previously treated with a CDK4/6 inhibitor. buff.ly/gkjdRPf

Ruth O'Regan summarizes the 2025 FDA approvals for HR+ metastatic breast cancer, including datopotamab deruxtecan, trastuzumab deruxtecan, and imlunestrant. Watch now in the Best of #SABCS25:
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#SABCSSnippets: Rahul Gosain of the Oncology Brothers talked with Marleen Kok at #SABCS25 about how lobular carcinoma—which comprises 10-15% of all invasive breast cancers—differs from ductal carcinoma.
buff.ly/r4mA3Vx @marleenkok.bsky.social @oncbrothers.bsky.social

Hope Rugo reviews biomarker subgroup results from the evERA phase III trial, updated EMBER-3 efficacy of imlunestrant in advanced breast cancer, and WISDOM 1.0 findings on risk-based screening. Watch now in the Best of #SABCS25: buff.ly/vDfAHmH @hoperugo.bsky.social

Hope Rugo shares the first positive results for an oral SERD (giredestrant) in the adjuvant setting and key findings from the phase III lidERA trial in ER+, HER2− early breast cancer. Watch now in the Best of #SABCS25:
https//buff.ly/fUHtwnq @hoperugo.bsky.social

#SABCSSnippets at #SABCS25: Julie Nangia and @ErikaHamilton9 discussed HER2CLIMB-05, which showed that adding tucatinib to 1st-line maintenance therapy with trastuzumab and pertuzumab delayed progression in patients with HER2+ metastatic breast cancer.
buff.ly/YIwYQEh @erikahamilton9.bsky.social

Janice Tsang reviews a year in metastatic breast cancer, highlighting key trial updates in TNBC, HER2+ and HR+/HER2− disease—including ASCENT, DESTINY-Breast, HER2CLIMB, EMBER-3 and SERENA-6. Watch now in the Best of #SABCS25: buff.ly/vDfAHmH

William Gradishar reviews key #SABCS25 findings in early breast cancer, including neoadjuvant trials TBCRC056 and OlympiA exploring PARP inhibitors and immunotherapy in BRCA-mutated disease. Watch now in the Best of SABCS®:
buff.ly/vDfAHmH

#SABCSSnippets: Virginia Kaklamani talked with Hope Rugo at #SABCS25 about the field of endocrine therapy, including data from the Phase III evERA Breast Cancer Study and from the Phase II ELEVATE Study.
buff.ly/Bw3mSWW @vkaklamani.bsky.social @hoperugo.bsky.social

#SABCSSnippets: Virginia Kaklamani talked with Laura Esserman about the results of the WISDOM 1.0 study, which demonstrated that risk-based breast cancer screening is safe, preferred by women, and identifies the highest risk individuals.
buff.ly/DFByGvB @vkaklamani.bsky.social

Close out #SABCS25 with the Year in Review and View from the Trenches sessions on Friday afternoon.

More details in SABCS Meeting News: buff.ly/NMwi7Nk

Experts will explore whether all patients with early-stage breast cancer need axillary staging during an #SABCS25 debate on Friday afternoon.

Learn more: buff.ly/dsX3CkF

Sara M. Tolaney, MD, MPH, AACR Outstanding Investigator Award for Breast Cancer Research recipient, will present an award lecture on Friday afternoon at #SABCS25.

Read more: buff.ly/Dnsf4Rd

Friday's Poster Spotlight Sessions at #SABCS25 covered a wide range of topics, including the application of AI to pathology and risk stratification, locoregional challenges, and CNS metastases.

#SABCS25 Patient Advocacy Spotlight: Marcela Mazo Canola, MD, and Laurel Pointer reflect on their relationship as physician and patient.

Read now in SABCS Meeting News: buff.ly/84wgwzX

Real Impact with Artificial Intelligence:
Johan Hartman, Tufia Haddad, Amrita Basu, and advocate Carole L Baas explored this topic in an #SABCS25 educational session moderated by Frederick M Howard.

Elie Rassy, Gustavo Werutsky, Sara Tolaney, and advocate Janice Cowden discussed "How to Treat TNBC" in an #SABCS25 educational session moderated by Marleen Kok.

Patients are at the heart of the SABCS mission. We thank our patient advocate attendees for their enthusiastic participation in the Symposium and for their critical contributions to the #SABCS25 program.

Targeting the Non-T Cell Microenvironment: Fatima Mechta-Grigoriou, Kelly Kersten, George Plitas, and advocate Cheryl Jernigan addressed this topic in an #SABCS25 State of the Art session moderated by Christos Sotiriou.

Management of the Axilla in Multidisciplinary Care: Giacomo Montagna, Lori Pierce, Sherry Shen, and advocate N. Beth Emery addressed this topic in an #SABCS25 Clinical Controversies session moderated by Tari A. King.
@sherryshenmd.bsky.social

Patient advocate Marissa Thomas, CEO of The Breast of Us, will speak during a Friday afternoon session at #SABCS25 on body image, hair loss, and skin health after cancer treatment.

Learn more in SABCS Meeting News: buff.ly/kVLAcSv

Wendy Woodward and François-Clément Bidard moderated today's General Session at #SABCS25. The clinical trials featured in the session included TBCRC-053, Alliance A011104/ACRIN 6694, and BOOG 2013-08.
@ibcradiation.bsky.social

Partnership for Progress:
#AACRFellows Dennis Slamon joined Debra A. Patt and Barbara Segarra-Vazquez to discuss the role of advocacy in breast cancer research and treatment during a special plenary lecture this morning at #SABCS25.

Another day of great science—including sessions on optimizing cardiac outcomes and treatment of triple-negative breast cancer, and the @theaacr.bsky.social Distinguished Lecture in Breast Cancer Research—will begin soon at #SABCS25.

Representatives from more than 25 patient advocacy organizations discussed their work with #SABCS25 attendees in the Patient Advocacy Pavilion during the exhibit show on Wednesday. The Pavilion remains open through Friday during exhibit hours.