Phylogenetic and dating analysis of ancient and modern sheeppox virus. A. Maximum-likelihood phylogeny of ancient and modern SPPV genomes with ≥5× coverage, rooted using LSDV and GTPV. Nodes with bootstrap support of 100 are indicated by blue circles; other bootstrap values are shown at the corresponding nodes. Clades composed exclusively of modern genomes are collapsed and shown as triangles, and branches corresponding to ancient genomes are highlighted in pink. The grey box delineates the SPPV clade. B. Maximum-likelihood phylogeny of SPPV genomes with placement of low-coverage ancient samples using PathPhynder (Martiniano et al., 2022). For clarity, only the SPPV portion of the phylogeny is shown. Samples are coloured by material type, and low-coverage genomes (<5×) placed using PathPhynder are indicated by red triangles. Nodes with bootstrap support of 100 are marked with blue circles; other values are shown at the corresponding nodes. Tip labels indicate sampling location and calibrated historical date. Host species, sequencing coverage, and sample age are shown as a heatmap adjacent to the tips. C. Time-calibrated Bayesian phylogeny of the SPPV clade, with samples coloured according to material type.
Biopathocodicology?? 🦠🧬🐑 (1/4)
Check out this groundbreaking new #aDNA #pathology paper by @louis-lhote.bsky.social @gingerhowley.bsky.social and colleagues!
www.biorxiv.org/content/10.6...
11.07.2025 18:11 —
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