Daniela Robles-Espinoza

Gracias a Alejandro López y a @elpaismexico.bsky.social por cubrir nuestro último estudio en #melanoma #acral, realizado estudiando pacientes mexicanos 🇲🇽

Con @pbasurto.bsky.social y @christianmolinaag.bsky.social en portada, investigadores clave en este estudio 🤓💻🧬🧫

Thank you :D

Gracias Mari! Abrazos!! 🍀

Actuación especial de @pbasurto.bsky.social

La UNAM, que no tiene perfil aquí en Bluesky (hay que presionar!) con su equipo de TV UNAM Global hicieron un pequeño video para contextualizar los resultados de nuestro estudio. Se los dejo por si le quieren echar un ojo, dura 2 minutos :p #HistoriasUNAM

youtu.be/WYwBzb2LN6s?...

Ancestry and somatic profile indicate acral melanoma origin and prognosis - Nature Analysis of the somatic and transcriptomic profile of 123 acral melanoma samples from Mexican patients helps understand tumour origins and prognosis, and highlights the importance of including samples from diverse ancestries in cancer genomics studies.

Nature research paper: Ancestry and somatic profile indicate acral melanoma origin and prognosis

go.nature.com/3OmsGVT

Thanks so much Peter, so nice to hear from you! I hope you have been doing well, and I hope we are able to meet again soon!!

Sometimes it's the only option 😂 hope you have been well!!! And to see you soon ☺️

Thank you Itai!! It took so so long 😅😅

Thanks for the kindness in review! I saw your name below.. 😊

We are also incredibly thankful to our editors and reviewers, who treated us with kindness and respect, and made this long journey interesting and enjoyable!

..and others. Finally, most importantly, really really thankful to patients and their families for accepting to form part of this study. We hope this helps lead to better treatments in the future!!

Alethia Alvarez and Dorian Ortega, from INCan, who helped us interpret these results clinically. And to all co-authors, thank you so much. Our wonderful funders @wellcometrust.bsky.social, @melanomaresearch.bsky.social, the Mexican government, our University, the Academy of Medical Sciences 🇬🇧 ...

And @christianmolinaag.bsky.social, who supported these studies since the beginning in a crucial way, @patriciapossik.bsky.social & @davidjadams.bsky.social, the eternal #LA #melanoma team, and Rob Judson-Torres and Rich White, who helped us interpret our results. Massive thanks to Hector Martinez..

We also find different gene expression and somatic profiles associated to patient survival. We believe this work illustrates the value of studying diverse populations in cancer research. Massive thanks to first author @pbasurto.bsky.social, who made it all happen, @estefvazquez.bsky.social ...

Here, we study #acral #melanoma tumours from Mexican patients. We find a correlation between BRAF mutation rate and European ancestry, and a potential different cell of origin (c-mel melanocytes) for BRAF-activated tumours compared to a v-mel cell of origin for non-BRAF mutated tumours.

Ancestry and somatic profile indicate acral melanoma origin and prognosis - Nature Analysis of the somatic and transcriptomic profile of 123 acral melanoma samples from Mexican patients helps understand tumour origins and prognosis, and highlights the importance of including samples...

We are very happy to see our study finally appear online @nature.com! This has been work of nearly 10 years in collaboration with the National Institute of Genome Medicine 🇲🇽, the National Cancer Institute 🇲🇽, the @sangerinstitute.bsky.social and others ⬇️

www.nature.com/articles/s41...

Somatic mutational signatures describe where mutations come from 🧬. But do they shape how proteins function? In our new preprint, we show that mutational processes can systematically rewire cellular signaling networks by altering short linear motifs (SLiMs). Preprint: www.biorxiv.org/content/10.6...

From twitter, I miss being able to see what people were talking about with #trends

Wow Theo this is so cool! Again :D amazing

Bluesky Map Interactive map of 3.4 million Bluesky users, visualised by their follower pattern.

I made a map of 3.4 million Bluesky users - see if you can find yourself!

bluesky-map.theo.io

I've seen some similar projects, but IMO this seems to better capture some of the fine-grained detail

Ahora, Evelia Coss nos cuenta sobre los #vieRnes de #bioinformatica que coordina en el @liigh-unam.bsky.social, que buscan fomentar la formación y crecimiento de la bioinformática por medio de cursos gratuitos #DiasAcademicos2026

Únete: viernes bioinformatica.github.io/

Finalmente, la última sesión científica la cierra Laura Figueroa, investigadora postdoctoral en el grupo de @delvecchyo.bsky.social, quien nos está platicando sobre una reconstrucción palaeogenómica del desierto chihuahuense #DiasAcademicos2026 @liigh-unam.bsky.social

La siguiente charla fue impartida por @aleconadeasombrosa.bsky.social, del grupo de @delvecchyo.bsky.social, quien nos habló sobre las señales de una posible relajación del impacto de la selección natural en los últimos 10,000 años #DiasAcademicos2026 @liigh-unam.bsky.social

Ahora estamos escuchando el último bloque de charlas, a cargo del grupo de @delvecchyo.bsky.social! Primero, Vale Cabrera, estudiante de la @lcgej.bsky.social, nos habla de selección direccional y su impacto en la variación fenotipica #DiasAcademicos2026 @liigh-unam.bsky.social

Ahora escuchamos a Andrea Zermeño, del grupo de @surh.bsky.social, quien nos cuenta un proyecto muy interesante sobre interacciones entre microorganismos en el océano 🌊 #DiasAcademicos2026 @liigh-unam.bsky.social

Ahora es el turno del grupo de @surh.bsky.social! Comenzamos con una charla de la estudiante de maestría Yetel Ramírez, quien nos contó de su plan de estudiar el microbioma en pacientes con #lupus #DiasAcademicos2026 @liigh-unam.bsky.social

Una excelente y muy activa sesión de posters en los #DiasAcademicos2026 @liigh-unam.bsky.social

Escuchamos a Renata Sandoval, estudiante de la @lcgej.bsky.social en el lab de @lumoralesr.bsky.social, quien nos contó sobre la dinámica de las frecuencias alelicas en los metagenomas de la fermentación de agave 🇲🇽🌱 #DiasAcademicos2026 @liigh-unam.bsky.social

También, escuchamos a Diego Morales, quien estudia en la Universidad Anáhuac y está trabajando en el grupo de @crisvanhout.bsky.social, hablarnos de factores demográficos y de estilo de vida que influencian el índice de masa corporal 🇲🇽 #DiasAcademicos2026 @liigh-unam.bsky.social