Silvia Surinova

a spongebob squarepants scene with a mailbox and a flower ALT: a spongebob squarepants scene with a mailbox and a flower

Hey @asms.org peeps. I’m running for VP for programs and I’d like your vote. Check out the asms web site for details and you will see an email with voting instructions in the near future. I approach this position with lots of experience organizing scientific conferences & I ❤️ asms. Please re-sky.

Join us for the 73rd London Biological Mass Spectrometry Discussion Group meeting - 23rd Sept at University of Westminister.

Attendance is free thanks sponsorship by @sciex.bsky.social

See our website for the agenda: lbmsdg.org

Registration is via eventbrite: www.eventbrite.co.uk/e/73rd-londo...

Thio-NHS esters are non-innocent protein acylating reagents - Nature Communications N-Hydroxysuccinimide (NHS)-ester derivatives are one of the most widely used acylating agents. In this work, the authors report that ring-opening reaction of the succinimide to afford N-succinamide de...

We (with @bendavisgroup.bsky.social) were using NHS chemistry for some protein conjugation when we noticed some odd prominent side products. It turns out thio-nhs reagents (a major class of reagents) has some notable side reactions that happen all the time.

www.nature.com/articles/s41...

Portal Biotech Raises $35 Million Series A, Leveraging AI to Deliver the World’s First Full-Length Single-Molecule Protein Sequencer Portal Biotech Raises $35 Million Series A, Leveraging AI to Deliver the World’s First Full-Length Single-Molecule Protein Sequencer...

www.globenewswire.com/news-release...

That is a *serious* Series A for a hardware proteomics tech! I think Alamar was something like $14M, Seer was $6M, nautilus $27M, so this is hefty. I'm itching to get some demo samples done and get quote estimates.

Multiplexed phosphoproteomics of low cell numbers using SPARCE Communications Biology - Streamlined Phosphoproteomic Analysis of Rare CElls (SPARCE) enables robust quantification of proteomes and phosphoproteomes from just 1,000 FACS-sorted cells, advancing...

SPARCE is out!🎉 A new workflow for Multiplexed phosphoproteomics of low cell numbers rdcu.be/ejrte, co-led by @emgaiz.bsky.social and Xiuyuan Chen. Also see Behind the Paper go.nature.com/3RYwsDz for main take aways. Thanks to @uclmedsci.bsky.social and @cruk-cityoflondon.bsky.social for support.

Addressing NHS chemistry: Efficient quenching of excess TMT reagent and reversing TMT-over labelling in proteomic samples by methylamine N-Hydroxysuccinimide (NHS) ester chemistry is used extensively across proteomics sample preparation. One of its increasingly prevalent applications is in isobaric reagent-based quantitation such as iT...

A basic solution to a very common problem.

collab with @kusterlab.bsky.social and @bendavisgroup.bsky.social

www.mcponline.org/article/S153...

I am delighted to have been gifted this beautiful necklace with a hand-drawn orbitrap from @emgaiz.bsky.social. I could not have wished for a better student or gift! Thank you Dr Emily 🤗

Come and work with us at UCL!

We are looking for a Computational Scientist for #proteomics to characterise the regulatory phosphoproteome by integrating multiomic data layers.

#TeamMassSpec

Congratulations to Dr Gaizley @emgaiz.bsky.social on passing her viva 👩🏼‍🎓 Emily was co-supervised by Prof Tariq Enver and developed #proteomics technologies for the study of quiescence. Big thanks to her examiners Prof Jesper Olsen @jespervolsen.bsky.social and Prof Bart Vanhaesebroek!

#TeamMassSpec

PhosX is out! doi.org/10.1093/bioi... Leveraging the latest kinase specificity maps by the Cantley, Yaffe, and Turk labs and a rank sum statistic we created PhosX so now we can predict activities for nearly all kinases in your phosphodata, including the understudied ones. Check it out!

Few quick notes for new followers 🦋 Please add some bio ✍️ before starting to follow. I still have time to go through new followers and skip those without bio just as a precaution. If you add it later, I (and others) may not return to follow back and I would hate to miss out on great scientists👩‍🔬🧑‍🔬!

UCL – University College London UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

Exciting opportunity to come and work with us at UCL Cancer Institute. We are looking for a Computational Scientist for #proteomics to characterise the regulatory phosphoproteome and apply data integration with other multiomics approaches. #TeamMassSpec

Details:
www.ucl.ac.uk/work-at-ucl/...

the man is wearing a suit and tie and clapping his hands . ALT: the man is wearing a suit and tie and clapping his hands .

@emgaiz.bsky.social gave a beautiful talk at the recent HUPO conference in Dresden. She had a done a lot of work and made some nice insights.