Lauren Jones

Intestinal macrophages modulate synucleinopathy along the gut–brain axis - Nature Muscularis macrophages, housekeepers of enteric nervous system integrity and intestinal homeostasis, modulate α-synuclein pathology and neurodegeneration in models of Parkinson’s disease, and understanding the accompanying mechanisms could pave the way for early-stage biomarkers.

Nature research paper: Intestinal macrophages modulate synucleinopathy along the gut–brain axis

go.nature.com/4rg6DOI

04.02.2026 07:48 — 👍 28    🔁 9    💬 0    📌 1

Postdoc job alert!

Come work with me on my MRC-funded fellowship on stress and appetite 🧠🌭 at @warwicklifesci.bsky.social

5 years of behaviour, circuit manipulations, neuroanatomy, electrophysiology and transcriptomics👨‍🔬🤓

Oh and Warwick is beautiful😍

Info here: tinyurl.com/yzmf24r3
Please share.

05.01.2026 11:54 — 👍 8    🔁 7    💬 1    📌 0

Brain-Derived GLP-1—Understanding the Physiological Function and Anti-obesity Potential of Preproglucagon Neurons Abstract. Glucagon-like peptide-1 (GLP-1) is produced within the central nervous system (CNS) by preproglucagon (PPG) neurons. This brain-derived GLP-1, ra

Our latest thoughts on brain-derived GLP-1 are out in Endocrinology now.

academic.oup.com/endo/article...

24.11.2025 16:04 — 👍 5    🔁 3    💬 0    📌 0

Thank you so much Dan, and @bsneuroendo.bsky.social for giving me the opportunity to share our latest work!
I had the best time meeting new and old friends!

05.09.2025 10:37 — 👍 5    🔁 0    💬 0    📌 0

Thrilled to see our review published, focusing on GLP-1 in eating and as an obesity treatment.

Grateful for the opportunity and guidance @drdanbrierley.bsky.social

22.01.2025 16:15 — 👍 4    🔁 0    💬 0    📌 0