Gretchen Diehl Lab

YouTube video by MicrobeTV Immune 100: Immune turns 100

Immune 100: Immune turns 100! 🎉🎉🎉 Filmed live at The Incubator, Gretchen Diehl and Shruti Naik join the Immune team and an audience in NYC to celebrate!

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Intestinal epithelial TLR5 signaling promotes barrier-supportive macrophages Colonic stem cell TLR5 sensing of microbes promotes macrophage recruitment and maturation to support intestinal barrier repair.

Researchers from the lab of MSK immunologist Dr. Gretchen Diehl are shedding new light on how intestinal stem cells sense microbes and protect the gut. Read their new study, just out in @science.org #ScienceImmunology.

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Intestinal epithelial TLR5 signaling promotes barrier-supportive macrophages Colonic stem cell TLR5 sensing of microbes promotes macrophage recruitment and maturation to support intestinal barrier repair.

Huge congrats to Ming-Ting Tsai on publishing his thesis work in Science Immunology! Ming-Ting dissects a mechanism of E. coli-driven intestinal barrier repair, highlighting TLR5 as a key receptor for recruiting CCR2+ macrophages to the colonic lamina propria. 🎉
www.science.org/doi/10.1126/...