Schematic overview of NEP analysis steps (Neighborhood definition, Quantification and NEP score) and the systematic method performance comparison using simulated data for cohort distinction.
1/
Ever wondered how to best quantify cell-cell neighbor preferences in tissues?
We compared 9+ neighbor preference (NEP) methods for analysing spatial omics data and propose a novel approach that combines the most relevant analysis features which we call COZI π¬β¨
Read more: doi.org/10.1101/2025...
15.04.2025 15:50 β π 36 π 12 π¬ 1 π 2
The first version of NetworkCommons is now published in Bioinformatics. Next, weβll focus on involving more of the network biology community.
academic.oup.com/bioinformati...
In parallel, weβll continue expanding benchmarks and developing new applications.
Interested in contributing? Reach out! β¬οΈ
20.02.2025 16:30 β π 44 π 20 π¬ 0 π 1
We are very happy to present our work on N-glycoproteomics!π¬ Our method enables the selective enrichment and precise quantification of intact N-glycopeptides to explore the dynamics of glycosylation microheterogeneity.
www.nature.com/articles/s41...
10.02.2025 10:20 β π 40 π 19 π¬ 1 π 3
Lol
16.01.2025 08:23 β π 3 π 0 π¬ 0 π 0
GRETA graphical abstract
We present Gene Regulatory nETwork Analsyis (GRETA), a framework to infer, compare and evaluate gene regulatory networks #GRNs. With it, we have benchmarked multimodal and unimodal GRN inference methods. Check the results here π
Paper: doi.org/10.1101/2024.12.20.629764
Code: github.com/saezlab/greta
23.12.2024 08:43 β π 126 π 46 π¬ 2 π 5
1/11 - With Karin Mitosch and ClΓ©ment Potel + colleagues in Savitski lab and @typaslab.bsky.social @embl.org, Iβm very happy to share our discovery of a hyper-promiscuous phage protein kinase (T7K) which broadly deactivates bacterial defenses! π¦
www.biorxiv.org/content/10.1...
23.12.2024 07:29 β π 37 π 16 π¬ 1 π 2
MOFA
Multi-Omics Factor Analysis
Multi-Omics Factor Analysis (MOFA) has become pretty widely used as a first-line tool to look at multi-modal (omics) data from multiple samples.
The method's algorithm is clearly valuable, but I'm starting to realize that for many users, just as valuable is ... (1/2)
biofam.github.io/MOFA2/
18.12.2024 13:01 β π 16 π 2 π¬ 1 π 0
A meme of TinTin speaking to Captain.
Captain, looking defeated, says "2020 has been a hell of a year"
TinTin replies "Captain, it's almost 2025β
13.12.2024 20:33 β π 25302 π 4107 π¬ 192 π 175
π¨π¦ π§¬Less than one month to register with an Early Birth rate!! Join us next year to discuss all things ancient pathogen genomics in beautiful QuerΓ©taro πͺ
π²π½
liigh.unam.mx/apg
03.12.2024 11:55 β π 6 π 3 π¬ 0 π 1
We have created a starterpack to make it easier to follow current members and alumni from our lab, check it out π (DM us if we forgot about you)
Also juliosaezrod.bsky.social has recently joined Bluesky
go.bsky.app/5ZtPHPz
20.11.2024 13:10 β π 29 π 12 π¬ 1 π 2
Hi everyone!
Here's a starter pack of genomics scientists trained in Mexico π²π½ including from #LCG-UNAM #LCG-EJ-UNAM undergrads, #RMB / #NNB-UNAM / @cdsbmexico.bsky.social workshops, and more
It's in an early stage and I'm trying to get more to join us here at #AcademicSky
go.bsky.app/5bWBN5V
08.11.2024 18:55 β π 39 π 23 π¬ 2 π 1
Biostatistician @IDEXX formerly at harvardmed, @BIDMChealth, @nasa. Big data, clinical trials, and medical diagnostics. Mainer. Opinions are my own. he/him
Postdoc @broadinstitute.org @harvard.edu #MGH - Immunogenomics - PhD in Genomics𧬠@cam.ac.uk @sangerinstitute.bsky.socialπ¬ #LCG-UNAM
Visualisation and graphics @posit.co
Classic Generative Art Weirdo using π€ and R: http://thomaslinpedersen.art and http://deca.art/thomasp85
he/him
Professor at ETH Zurich, PI of the Systems Physiology lab, https://bsse.ethz.ch/lsp, captivated by cellular interactions, precision medicine, spatial biology, and the tumor microenvironment.
Experimental ecology and evolution | microbes | evolution of metabolic interactions | cooperation | bacterial multicellularity.
The AI-powered developer platform to build, scale, and deliver secure software.
Computing all things single-cell | Postdoc at Genentech @MarioniLab | Steering council at scverse.org
Group leader at the Centre for Genomic Regulation (CRG), Barcelona, Spain. Interested in cancer evolution and human population genetics.
A team of creative, unconventional and computational statisticians who develop R mixOmics for the biological community. Omics and microbiome unraveller.
As a joint venture of the University of Basel and the University Hospitals Basel, the Department of Biomedicine (DBM) brings together basic and clinical scientists to advance our understanding of health and disease.
π€ AlternativeTo is the ultimate hub for discovering new and exciting software, no matter what platform you're on! Whether you're looking for apps for Windows, Mac, Linux, online services or mobile devices, we've got you covered!
The Netherlands Cancer Institute (NKI): at the international forefront of cancer research and treatment for over 100 years.
Oncode Institute is an independent institute dedicated to understanding cancer and translating research into practice more efficiently. Learn more about Oncode Institute: https://oncodeinstitute.nl
Researcher at Heidelberg University @saezlab.bsky.social | #ML and AI in #single-cell and #spatial #omics
BSc in Genomic Sciences at UNAM Juriquilla. 𧬠Interested in aDNA, speciaton, conservation & metagenomics.
Student at the Undergraduate Program in Genomic Sciences at CCG, UNAM
Biophysics enthusiast!
The funder-researcher collaboration and open-access publisher for research in the life and biomedical sciences.
Follow @eLifeCommunity.bsky.social