Simon Gates

Free stickers suitable for flag-bearing lampposts. Send a large A4 envelope with a 1st class large stamp to me at Bragg Office, PO Box 6830 Bridport DT6 9BH and I’ll send you a sheet. #ReclaimtheFlag 🏴󠁧󠁢󠁥󠁮󠁧󠁿🏴󠁧󠁢󠁳󠁣󠁴󠁿🏴󠁧󠁢󠁷󠁬󠁳󠁿🇬🇧

IS THAT IT?
Pathetic.

Nathan Gill’s treachery puts him in same league as the “Cambridge Five” Reform’s Russia connections may endanger our security – time for a public inquiry

Reform’s Russia connections are a danger to our national security.

It’s time for a public inquiry.

Flexible Goal-Drive Bayesian Design - video of presentation is now available at www.fharrell.com/talk/gdesign/ #Statistics #StatsSky #bayes #rct

Why randomized controlled trials matter and the procedures that strengthen them Randomized controlled trials are a key tool to study cause and effect. Why do they matter and how do they work?

Read more about RCTs and why they’re so important: ourworldindata.org/randomized-c...

BMJ. 2001 Sep 29;323(7315):711. Separate vaccines could endanger children Zosia Kmietowicz 1 Author information Copyright and License information PMCID: PMC1121280 Experts have declared that the current fad among some parents to give their children single injections against measles, mumps, and rubella rather than the triple MMR vaccine is a “backward step” that could endanger their children's health. There is no evidence that using separate vaccines to immunise children against these childhood diseases is either safe or effective

This is from @bmj.com from 24 years ago, for goodness sake (it was countering Wakefield’s anti-vaxx nonsense)

RFK Jr, Trump and the MDs at the press conference today who are their anti-vaxx lackeys—Drs Oz, Bhattacharya, & Makary—are playing such a dangerous game 😢

Trump channelling Andrew Wakefield.

The Bone & Joint Journal. Extract from article titled 'Clinical trials in Trauma and Orthopaedics: time to think Bayesian?'

The use of Bayesian methods in the design of trials and the analysis of the findings provides several potential benefits, which may be particularly applicable in Trauma & Orthopaedic surgery.

#ClinicalTrials #BayesianStatistics #RCTs #OrthoSky
@docfarrow.bsky.social

ow.ly/xeXm50WRwZN

Join us at #atmc25 as we explore "Better Trials Through Better Methods"
Invited speakers and program details now available - more at www.atmc25.com

Secure your ticket today! Early🐦 must end 26/9

What is executive function? In a recent post about the abilities and personality traits required to complete a PhD program, I mentioned the concept of executive function. From some of the responses I received, I gather that it’s...

I confused some people recently when I talked about executive function, so I wrote an entire post on the topic.
blog.genesmindsmachines.com/p/what-is-ex...

Latest in making it up as you go along

Right side of history 🏴󠁧󠁢󠁳󠁣󠁴󠁿🏴󠁧󠁢󠁳󠁣󠁴󠁿 #ScottishIndependence #StillYes

The Tories also did this if I remember correctly

Please add your name to our open letter urging Ministers to act now lnkd.in/ejJ2nrva 3/3

They’re excluded from Government support that's available for other museums, art galleries and theatres.

The Association of Science and Discovery Centres is calling on the Department for Science, Innovation and Technology (DSIT) to safeguard these vital institutions for the next generation… 2/3

For over 25 years, science and discovery centres have been at the heart of inspiring millions of people to explore, question, and be part of UK science and technology.

But they're seriously under threat… 1/3

Vaccine warning for England as one in five children start school unprotected Experts say country needs ‘wake up call’ with levels far below those needed for herd immunity

Measles, mumps, rubella, diphtheria, polio, tetanus.

Diseases that used to terrorise families, killing children & babies in their thousands.

Now we have vaccines - safe & miraculous life savers.

Please, parents, use them.

Protect your precious children 🩷

www.theguardian.com/society/2025...

An open letter to Nigel Farage - Bishop Steven's Blog Bishop Steven writes an open letter in response to Nigel Farage MP's immigration policy which was launched in Oxford this week.

A courteous but very impressive rebuke to Nigel Farage from the Bishop of Oxford.

"I heard no compassion in what you said...".

"I disagree profoundly with your attempts to ... increase fear of the stranger in our communities".

Do read.
blogs.oxford.anglican.org/an-open-lett...

Thanks - I broadly agree with the methodology hub article but I think they are not nearly forceful enough. Loads of single arm trials get conducted that should have been randomised (or at least that's my impression!).

See also Rishi Sunak

Registration is open for the 2025 Australian Trials Methodology Conference (held on 20th November). For more information please visit:
atmc25.com/home

#atmc25

Yes absolutely.
"Effectiveness"
"Evaluate"
It's just an audit.

Real world data have many strengths - coverage; scale; & ease of access. Proponents suggest they are thus ideal for estimating treatment effects – suggesting results will be more generalisable than those from randomised trials (and avoid the costs/labour of running trials) 2/9

oops typo
posterior

But why do they have to drag "statistical significance" into it? Just report the postrior probabilities.

Happy for people to contact me if you have any queries.

Biostatistician - Cancer Research UK Clinical Trials Unit - 105965 - Grade 7 This post is for a Biostatistician to be the main statistical scientist for a methodological project on improving statistical methods for the design and analysis of clinical trials in paediatric cance...

Job available for a statistician to work on a clinical trials methodology project on improving statistical methods for paediatric cancer ttrials.

Cancer Research UK Clinical Trials Unit, University of Birmingham

Closes 22 September

edzz.fa.em3.oraclecloud.com/hcmUI/Candid...

I think this issue is one of the most appealing aspects of Bayes. With Bayes the posterior distribution is the basis for inference, and it is invariant to the design.

A letter from myself and @jdwilko.bsky.social that expands on this a bit more. Thanks to Fertility and Sterility for the opportunity.

doi.org/10.1016/j.fe...