Igor Brodsky's Avatar

Igor Brodsky

@brodskyigorlab.bsky.social

Innate immunity/host-pathogen interactions. Husband, father, former Soviet immigrant. Opinions my own.

4,564 Followers  |  1,311 Following  |  431 Posts  |  Joined: 31.10.2023
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Posts by Igor Brodsky (@brodskyigorlab.bsky.social)

This is what authoritarians are never gonna understand: average, everyday citizens do not like watching paramilitary thugs brutalize children. All the vaporware memes in the world can't fix that for them

14.02.2026 15:53 β€” πŸ‘ 3225    πŸ” 833    πŸ’¬ 32    πŸ“Œ 20

Plants use cell-surface and intracellular receptors that collaborate to detect pathogens🦠. We discovered that a key #ubiquitin recognition event recruits both receptor types into an unexpected dual receptor complex that boost the translation of defence proteins and establishes robust #PlantImmunityπŸ‘‡πŸΎ

09.02.2026 09:57 β€” πŸ‘ 66    πŸ” 44    πŸ’¬ 2    πŸ“Œ 1
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We will never get more than what we celebrate Why allowing the Trump administration to reset our expectations will harm US science

Don’t listen to anyone trying to suggest the FY2026 budget bill saved science.

The bill has some wins (and I am grateful to those you worked with and from within Congress for those wins).

We have a lot of work to do before we rest.

open.substack.com/pub/sciencea...

07.02.2026 17:38 β€” πŸ‘ 28    πŸ” 9    πŸ’¬ 1    πŸ“Œ 0
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Every American needs to watch this:

05.02.2026 20:41 β€” πŸ‘ 20516    πŸ” 10280    πŸ’¬ 579    πŸ“Œ 981

Just a bit…

06.02.2026 04:24 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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The Late Show on Instagram: "Leave it to Shakespeare and @ianmckellen to so eloquently speak of man’s mountainish inhumanity. See Ian McKellen in AN ARK, a new play for mixed reality, at @theshedny ... 503K likes, 13K comments - colbertlateshow on February 4, 2026: "Leave it to Shakespeare and @ianmckellen to so eloquently speak of man’s mountainish inhumanity. See Ian McKellen in AN ARK, a new pl...

Powerful Shakespearian monologue from Ian McKellen on Colbert.

Just a bit applicable to today...

www.instagram.com/reels/DUXMaL...

06.02.2026 00:25 β€” πŸ‘ 33    πŸ” 7    πŸ’¬ 3    πŸ“Œ 1

If you need to find a figure skater to cheer on during the Olympics, here’s a great one from my small town in CT
#TeamUSA

06.02.2026 01:15 β€” πŸ‘ 27    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0

In brief, this maneuver:
- effectively converts employee status to "at-will" (meaning they can be fired for any--or no--reason),
- redirects whistleblower complaints to internal agency counsel,
& takes away these civil servants' rights to appeal adverse personnel actions.

06.02.2026 02:30 β€” πŸ‘ 134    πŸ” 84    πŸ’¬ 2    πŸ“Œ 2

Without the Washington Post health and science team the public would have known far less about what’s been happening at NIH and CDC this year.

Post reporters have done absolutely key reporting, for example a profile on NIH cancer researcher Steve Rosenberg speaking up about damage to his work.

05.02.2026 17:35 β€” πŸ‘ 32    πŸ” 12    πŸ’¬ 2    πŸ“Œ 1
An email from the Internet Archive staff indicating that they have good backups of the NIH Record.

An email from the Internet Archive staff indicating that they have good backups of the NIH Record.

Good news.

I reached out to the Internet Archive folks to let them know about the discontinuation of the NIH Record.

As I have found on numerous occasions over the past year, they are "on in".

A great organization and an increasingly important resource.

03.02.2026 00:16 β€” πŸ‘ 58    πŸ” 9    πŸ’¬ 1    πŸ“Œ 0
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Right now, Democrats have the power to defund and abolish ICE. We should do it. This is about right and wrongβ€”and the murder we are seeing on the streets is just plain wrong. Anyone who supports funding DHS and ICE is supporting the murder of Americans. We can stop this.

28.01.2026 23:48 β€” πŸ‘ 6899    πŸ” 1768    πŸ’¬ 316    πŸ“Œ 317
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β€œWe will not be intimidated into silence.”

β€”Dr. Leonard Bright, AAUP Texas A&M

This fight is bigger than Texas A&Mβ€”it is about whether public universities will serve democracy or fear it.

@tamu-aaup.bsky.social
@texasaft.org
@texasaaup.bsky.social
@movetexas.bsky.social

29.01.2026 23:35 β€” πŸ‘ 94    πŸ” 35    πŸ’¬ 2    πŸ“Œ 0

Just donated on behalf of @sunnyshinlab.bsky.social & myself ✊Let’s goooo!!

29.01.2026 23:51 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Fuel the fight! β€” STAND UP FOR SCIENCE

Ok people!!!

I believe we may be taking March 7th NATIONAL!

This will require financial support. Last year, nationwide, the protests cost $75,000. We need all the help we can get!

Help us fuel the fight here: www.standupforscience.net/donate

@standupforscience.bsky.social
#standupforscience

29.01.2026 21:06 β€” πŸ‘ 17    πŸ” 13    πŸ’¬ 1    πŸ“Œ 2
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U.S. government has lost more than 10,000 STEM Ph.D.s since Trump took office A Science analysis reveals how many were fired, retired, or quit across 14 agencies

Incredible self own for the US. The damage being done to the US scientific enterprise is generational. We will look back on this as a tipping point where the US chose all on its own to stop leading the world in science.

www.science.org/content/arti...

28.01.2026 11:46 β€” πŸ‘ 1496    πŸ” 832    πŸ’¬ 82    πŸ“Œ 54
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US science after a year of Trump: what has been lost and what remains A series of graphics reveals how the Trump administration has sought historic cuts to science and the research workforce.

US science after a year of Trump

A series of graphics reveals how the Trump administration has sought historic cuts to science and the research workforce.

www.nature.com/immer...
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28.01.2026 13:03 β€” πŸ‘ 15    πŸ” 14    πŸ’¬ 1    πŸ“Œ 1
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A prophage-encoded abortive infection protein preserves host and prophage spread - Nature A Gifsy-1 prophage–encoded higher eukaryotes and prokaryotes nucleotide-binding protein, HepS, senses Siphoviridae infection, activates abortive defence by cleaving host transfer RNAs, blocks rival ph...

A prophage-encoded abortive infection protein preserves host and prophage spread www.nature.com/articles/s41...

28.01.2026 19:13 β€” πŸ‘ 42    πŸ” 20    πŸ’¬ 0    πŸ“Œ 2

πŸ˜±πŸ™€

28.01.2026 13:13 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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William H. Foege, Key Figure in the Eradication of Smallpox, Dies at 89 His containment strategy helped wipe out the disease in the 1970s, one of the world’s greatest public health triumphs. He also led the C.D.C. and promoted childhood vaccination worldwide.

William Herbert Foege .... you should know him: one of the foremost persons responsible for eradicating smallpox. He died yesterday, January 24, 2026 ..... the day the USA pulled out of the WHO. It is all so terrible sad and stupid.

www.nytimes.com/2026...
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25.01.2026 16:40 β€” πŸ‘ 81    πŸ” 42    πŸ’¬ 1    πŸ“Œ 1

Today’s retreat is absolutely an attempt to take pressure off of Congress to rein in ICE so that a funding package can get through.

That pressure has been effective. We can celebrate Minneapolis’ win but we need to keep the pressure on. They’re not going to stop forever.

26.01.2026 21:05 β€” πŸ‘ 4741    πŸ” 1326    πŸ’¬ 134    πŸ“Œ 66
Flyer with announcement of the FEBS advanced course in Amsterdam

Flyer with announcement of the FEBS advanced course in Amsterdam

Join us in Amsterdam for a FEBS advanced course on "Functional Imaging of cellular dynamics" from 31st of May - 6th of June 2026
Info: microscopy2026.febsevents.org

27.01.2026 11:06 β€” πŸ‘ 24    πŸ” 16    πŸ’¬ 0    πŸ“Œ 0

β€œInstead, build your reputation on substance. Do good work that matters to you and can be explained to others. The format and funding will change. The value of your genuine contribution won't…the quality of your thinking and your approach will always matter.”

27.01.2026 05:09 β€” πŸ‘ 19    πŸ” 5    πŸ’¬ 1    πŸ“Œ 1

Nearly 15% (over 10,000 people) of the total number of Ph.D.s in science, technology, engineering, and math or health fields employed at the end of 2024 left their jobs in 2025. This is a science extinction event in the US. Rebuilding the lost expertise will take decades

27.01.2026 04:34 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
(next to an image of masked ICE agents) NO KINGS MASS CALL

EYES ON ICE: DOCUMENT AND RECORD

GET THE TOOLS YOU NEED TO EXERCISE YOUR RIGHTS AS FEDERAL AGENTS TERRORIZE OUR COMMUNITIES.

MONDAY, JANUARY 26
8PM EST / 5PM PST
(No Kings logo)

(next to an image of masked ICE agents) NO KINGS MASS CALL EYES ON ICE: DOCUMENT AND RECORD GET THE TOOLS YOU NEED TO EXERCISE YOUR RIGHTS AS FEDERAL AGENTS TERRORIZE OUR COMMUNITIES. MONDAY, JANUARY 26 8PM EST / 5PM PST (No Kings logo)

TONIGHT: Join the mass call on documenting and recording law enforcement encounters. We’ll discuss how you can keep taking action as federal agents terrorize our communities. Using our constitutional right to document and record ICE & CBP is more important than ever: www.mobilize.us/nokings/even...

26.01.2026 13:27 β€” πŸ‘ 1174    πŸ” 612    πŸ’¬ 26    πŸ“Œ 29

This is one of the things that I find is most shocking to people outside Minnesota who don’t realize it yetβ€”the scale at which everyone who isn’t white has been forced into a spectrum of hiding.

Very good article drawing out the Tahrir Square comparison.

26.01.2026 04:01 β€” πŸ‘ 4475    πŸ” 1881    πŸ’¬ 60    πŸ“Œ 67
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William H. Foege, Key Figure in the Eradication of Smallpox, Dies at 89

Bill Foege, a health giant who led the eradication of smallpox and then led the CDC, has died. Bill's commitment to humanity and to selfless leadership contrasts with the fecklessness of today's health leaders who try to undermine vaccines. RIP, Bill. www.nytimes.com/2026/01/24/u...

25.01.2026 14:26 β€” πŸ‘ 57    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0
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January 24, 2026 This morning, on a street in Minneapolis, at least seven federal agents tackled and then shot and killed Alex Jeffrey Pretti, a 37-year-old ICU nurse for the local VA hospital.

January 24, 2026

25.01.2026 06:01 β€” πŸ‘ 2242    πŸ” 803    πŸ’¬ 101    πŸ“Œ 112
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AOC IS πŸ’― CORRECT.......

25.01.2026 08:32 β€” πŸ‘ 1118    πŸ” 527    πŸ’¬ 41    πŸ“Œ 30

Since you may be stuck inside due to the blizzard, today would be a good day to call your senators & tell them how pissed off you are

25.01.2026 13:23 β€” πŸ‘ 114    πŸ” 49    πŸ’¬ 0    πŸ“Œ 3
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TincherSealedWitnessDec012426.PDF

This statement from an eyewitness to the Minnesota murder of Mr. Pretti is gut wrenching, from beginning to end. Please disseminate it as you see fit.
www.documentcloud.org/documents/26...

25.01.2026 11:15 β€” πŸ‘ 1068    πŸ” 618    πŸ’¬ 53    πŸ“Œ 40