Phil Corlett

Optical illusion of a woman bent over some papers. Her sunglasses are pushed up and she is wearing a hair band so the top of her head looks exactly like a Muppet face

Sorry I know the world is in a terrible fix but I've been laughing at this for ten minutes now

Honey Monster

Threading the needle: Practical considerations for merging theory-driven computational psychiatry with data-driven analytics to enhance precision health at scale The rapidly evolving field of computational psychiatry enables quantification of specific cognitive processes, and their underlying mechanisms, in a translational and potentially scalable manner, usin...

Excited to share our latest paper in which we discuss merging theory-and data- driven computational psychiatry in a large transdiagnostic cohort study (N=2400)

www.biologicalpsychiatrycnni.org/article/S245...

Christopher Pittenger, Godfrey Pearlson @annierhcheng.bsky.social @sobp-org.bsky.social

Regional cerebellar volumetrics in obsessive-compulsive disorder: An ENIGMA-OCD study Although subtle differences in cortico-striato-thalamo-cortical (CTSC) circuit structure and function are critical to the current understanding of the neurocircuitry in obsessive-compulsive disorder…

Adults with OCD exhibit significantly smaller volumes of the corpus medullare, left VIIb, and right VIIb compared to healthy controls, and these differences are mediated by medication status.

A drawing on the cover of the journal Neuron. Each section of the fan has a drawing of a mouse. Each mouse has a slightly different pose. The tassel of the fan resembles a neuron.

My first cover of 2026
"Spontaneous behavior is a succession of self-directed tasks"
www.cell.com/neuron/fullt...
#sciArt #Scicom #illustration #neuroskyence

Warm congratulations to The Brain Prize winners 2026, Professor David Ginty and Professor Patrik Ernfors, for their pioneering work on how the nervous system detects and processes touch and pain.

Karolinska Institutet
HHMI

#Neuroscience #BrainPrize2026

So cool to have @melaniemitchell.bsky.social with us as our @wutsaiyale.bsky.social Inspiring Speaker!

How does the brain generalize past experiences without confusing memories? 🧠

Our lab's newest preprint reveals a fundamental division of labor between the cortex and cerebellum that solves this problem. (Check out the cortex-cerebellum video below! 👇) 🧵

First preprint from the lab! Using intracellular recordings & analysis of 2-photon imaging data, we show that spiking & neuromodulatory input during experience drive a reorganization of visuomotor inputs in V1 layer 2/3 neurons, consistent with enhanced visuomotor cancellation - bioRxiv link below.

Topographically segregated mediodorsal-prefrontal loops exhibit distinct cue dynamics during learning and extinction https://www.biorxiv.org/content/10.64898/2026.03.02.709125v1

🚨Preprint! “Bayesian surprise tracks the strength of perceptual insight” - Work with @lindedomingo.bsky.social & @gonzalezgarcia.bsky.social

Ever wondered what factors influence the subjective experience of suddenly understanding a previously unclear input?

Click below:
doi.org/10.64898/202...

@jorge-morales.bsky.social giving our BSTP talk at Yale Psychiatry today. Perception is within and without. What a treat!

Orbitofrontal cortex drives predictive filtering of sensory responses - Nature Neuroscience Top-down projections from the orbitofrontal cortex carry predictive signals that grow with sound experience and suppress the auditory cortex via inhibitory circuits, revealing a predictive mechanism f...

Orbitofrontal cortex drives predictive filtering of sensory responses

www.nature.com/articles/s41...

#neuroskyence

Do You Agree? Do You Strongly Agree? The Effect of the Number of Response Categories on Response Processes and Verification of Substantive Hypotheses Abstract. This study investigates how the number and labeling of response categories in survey scales affect respondent behavior, psychometric properties,

This is consistent with earlier psychometric work that suggests 5-7 is the best response scale options, but good to see that the finding holds up in contemporary research. Also, good to see that labeling scales whether anchored or not has little impact on findings. academic.oup.com/ijpor/articl...

The inferred value of unchosen options spreads to related items in memory Counterfactual thinking — considering what could have come of choosing the other path — can facilitate inference. Previous studies have demonstrated t…

📢New paper out today in @cognitionjournal.bsky.social!

Does the value of an unchosen option — inferred through counterfactual reasoning — spread to related items in memory, similar to how the value of a chosen option — acquired through direct experience — does?

In short, yes!

Event segmentation during speech listening: The relative contributions of thematic structure and prosody: https://osf.io/x47cm

i gotta give credit where he's due when the dude goes to bat for the right thing he's great at it

Happy 14th Anniversary to one of the greatest moments in sports history

philosophy.

Deciding for others alters metacognition leading to responsibility aversion Making decisions on behalf of other people reduces decision confidence, which leads to responsibility aversion.

When we have to make a decision that affects other individuals—parents making decisions for children, for instance—our confidence in our decisions declines, making us averse to the responsibility.

Learn more in #ScienceAdvances: https://scim.ag/4cMK5ky

I do have a brand :-)

Want to use the word cromulent when, as a reviewer, authors send in replies that address my concerns, but don't assuage them.

"I found the author's response cromulent"

It means adequate, but it doesn't sound like that's what it means.

So excited about this preprint: Bottom-up and generative computations uniquely explain neural responses across the social brain

www.biorxiv.org/content/10.6...

An amazing colab led by @manasimalik.bsky.social with Minjae Kim, @tianminshu.bsky.social and @shariliu.bsky.social

Manasi's thread 👇

This is a robust response. I particularly liked this figure - clarifying why the original critique showed what it did, and what was missing @foxmdphd.bsky.social

Do our social interactions influence what we become aware of?

In our❗new preprint❗@danieljamesyon.bsky.social and I delve into this question: asking whether joint decision making in a detection task can bias awareness reports.

osf.io/preprints/ps...

🧵

Another excellent paper from benjyb.bsky.social showing how we align our perceptual judgements with others. Read and love it, and I trust you are already aware of this.

Why are tactile sensations suppressed during movements? In our new preprint, we explain this as optimal integration of sensory signals with an internal model.

Work led by @fatatai.bsky.social with Dimitris Voudouris, Katja Fiehler and @c-rothkopf.bsky.social

www.biorxiv.org/content/10.6...

The Journal of Neuroscience: 46 (8)

Very excited to share a Special Collection at the Journal of Neuroscience (@sfnjournals.bsky.social) - Central Questions for Social Neuroscience Research. This issue includes some of the latest perspectives on social neuroscience research. Please check it out!👇

www.jneurosci.org/content/46/8

A recent paper in @natureportfolio.nature.com raised concerns about the lesion network mapping method. Our team of 16 coauthors analyzed >1000 lesions and 34 symptoms and found that "The methodological foundations of lesion network mapping remain sound" www.biorxiv.org/content/10.6...

Compact deep neural network models of the visual cortex Nature - Parsimonious deep neural network models can be used for prediction of visual neuron responses.

DNN models of the brain are getting bigger. Are we replacing one complicated system in vivo with another in silico?

In new work, we seek the *smallest* DNN models of visual cortex, balancing prediction with parsimony.

It turns out these compact models are surprisingly small!

rdcu.be/e5H8G