Aleksandra Obrępalska-Stęplowska's Avatar

Aleksandra Obrępalska-Stęplowska

@stepelka.bsky.social

scientist, assoc. professor, molecular biology, plant-microbe-insect interactions, virology, microbiome coffee lover ☕

516 Followers  |  202 Following  |  51 Posts  |  Joined: 11.11.2024  |  1.8945

Latest posts by stepelka.bsky.social on Bluesky

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SALICYLIC ACID SENSOR1 reveals the propagation of an SA hormone surge during plant pathogen advance Salicylic acid (SA) is a key phytohormone that orchestrates immune responses against pathogens, including Pseudomonas syringae bacteria. The timing and extent of SA accumulation are tightly controlled...

SALICYLIC ACID SENSOR1 reveals the propagation of an SA hormone surge during plant pathogen advance | Science www.science.org/doi/10.1126/...

11.10.2025 08:58 — 👍 4    🔁 2    💬 0    📌 0
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Stenotrophomonas maltophilia impedes Bacillus biocontrol of tomato wilt disease by degrading its lipopeptide antibiotics Abstract. Harnessing antibiotic-producing microorganisms that antagonize pathogens represents a sustainable approach for plant disease management. However,

Stenotrophomonas maltophilia impedes Bacillus biocontrol of tomato wilt disease by degrading its lipopeptide antibiotics

-in #ISMEJournal

academic.oup.com/ismej/advanc...

24.09.2025 13:09 — 👍 5    🔁 3    💬 0    📌 0
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RNA virus infection and host immune responses The India I EMBO Lecture Course on “RNA virus infection and host immune responses” addresses cutting-edge research in emerging and reemerging RNA viruses, with particular emphasis on fundamental infe…

Interested in attending the EMBO Lecture Course, entitled "RNA virus infection and host immune responses," hosted in Faridabad, India, on 11 – 14 February 2026?

sign up here:
meetings.embo.org/event/26-rna...

11.09.2025 05:06 — 👍 1    🔁 1    💬 1    📌 0
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RNAcanvas: interactive drawing and exploration of nucleic acid structures Abstract. Two-dimensional drawing of nucleic acid structures, particularly RNA structures, is fundamental to the communication of nucleic acids research. H

🧪 #RNAsky

If you aren’t using RNAcanvas to draw your RNA structures and explore alternative structures, you are missing out! 56 citations in a year, with multiple ones in top journals like Nature, Science & Cell. Easy to use and packed with unique features! Try it!

academic.oup.com/nar/article/...

28.08.2025 22:33 — 👍 63    🔁 17    💬 1    📌 1
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Divergent viral phosphodiesterases for immune signaling evasion Cyclic dinucleotides (CDNs) and other short oligonucleotides play fundamental roles in immune system activation in organisms ranging from bacteria to humans. In response, viruses use phosphodiesterase...

Excited to share our new preprint co-led by @jnoms.bsky.social!

Here we reveal an exceptional diversity of viral 2H phosphodiesterases (PDEs) that enable immune evasion by selectively degrading oligonucleotide-based messengers. This 2H PDE fold has evolved striking substrate breath & specificity.

22.08.2025 19:02 — 👍 42    🔁 28    💬 2    📌 2
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Ancient hybridization underlies tuberization and radiation of the potato lineage Genomic and functional analyses reveal that the potato lineage originated from a homoploid interspecific hybridization event between the Tomato and Etuberosum lineages 8–9 million years ago. The alter...

So actually potato comes from tomato! 🤯🤯
A cross between a Solanum and a tuberosum derived in the actual potatoes! (Another) Incredible work by the lab of Sanwen Huang and colaborators

www.cell.com/cell/fulltex...

01.08.2025 08:38 — 👍 24    🔁 15    💬 0    📌 0

Out now in its final peer-reviewed form @asm.org's Journal of Virology!

doi.org/10.1128/jvi....

@dome-vienna.bsky.social @erc.europa.eu @amersocvirology.bsky.social

13.06.2025 21:14 — 👍 25    🔁 11    💬 0    📌 0

🚨Microbiologists!

Can you recommend a bacteria collection to deposit a strain type? I’m already working with @westerdijkinst.bsky.social (amazingly efficient), but have contacted others and no luck.

Thank you!

14.05.2025 20:16 — 👍 3    🔁 2    💬 1    📌 0

Registration is now open!
You can spread the word
psepb2025.pl

31.03.2025 08:40 — 👍 0    🔁 1    💬 0    📌 0
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On May 12th, we celebrate International Plant Health Day.
Nothing without them

#PlantHealth #OneHealth

12.05.2025 08:00 — 👍 1    🔁 0    💬 0    📌 0

So nice to see more and more work on visualizing interactions to dive into replication cycles… here with acanthamoeba and giant viruses ! Congrats @willemsenanouk.bsky.social !

11.05.2025 08:54 — 👍 10    🔁 5    💬 0    📌 0
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New "toy" almost ready

23.04.2025 09:26 — 👍 0    🔁 0    💬 0    📌 0
PSEPB2025 » Strona główna

We cordially invite you to the Experimental Plant Biology conference #PSEBP2025 which will be held at the University of Warsaw.

I will chair, together with Magda Krzymowska, a session on Plant Biotic Interactions.
Registration opens in a few days.

#plantsci
psepb2025.pl

20.03.2025 08:57 — 👍 7    🔁 6    💬 0    📌 1

Registration is now open!
You can spread the word
psepb2025.pl

31.03.2025 08:40 — 👍 0    🔁 1    💬 0    📌 0
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Planning and describing a microbiome data analysis - Nature Microbiology We provide guidance on the planning, execution and description of statistical analyses in microbiome studies.

A must-read for any microbiome researcher 🦠📐and a new addition to our #bestpractices series

Planning and describing a microbiome data analysis by @amydwillis.bsky.social and @davidandacat.bsky.social

www.nature.com/articles/s41...

21.02.2025 14:48 — 👍 58    🔁 26    💬 1    📌 1
PSEPB2025 » Strona główna

We cordially invite you to the Experimental Plant Biology conference #PSEBP2025 which will be held at the University of Warsaw.

I will chair, together with Magda Krzymowska, a session on Plant Biotic Interactions.
Registration opens in a few days.

#plantsci
psepb2025.pl

20.03.2025 08:57 — 👍 7    🔁 6    💬 0    📌 1
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How nidoviruses evolved the largest known RNA genomes | PNAS How nidoviruses evolved the largest known RNA genomes

www.pnas.org/doi/10.1073/...

20.03.2025 05:38 — 👍 2    🔁 1    💬 0    📌 0
Drosophila follicle showing retrotransposons (pink & yellow) expressed in somatic cells infecting the oocyte

Drosophila follicle showing retrotransposons (pink & yellow) expressed in somatic cells infecting the oocyte

1/ Transposable elements are often called "jumping genes" because they mobilize within genomes. 🧬
But did you know they can also jump 𝘣𝘦𝘵𝘸𝘦𝘦𝘯 cells? 🤯
Our new study reveals how retrotransposons invade the germline directly from somatic cells.
www.biorxiv.org/content/10.1...
A short thread 🧵👇

17.03.2025 11:56 — 👍 544    🔁 259    💬 11    📌 33
Close up of a raspberry whitefly (Trialeurodes ruborum). It is a flat, shiny black, wrinkly oval with evenly spaced rays of white wax surrounding the body's edge. It's on a purplish red leaf. The insect in life is only a couple millimeters long.

Close up of a raspberry whitefly (Trialeurodes ruborum). It is a flat, shiny black, wrinkly oval with evenly spaced rays of white wax surrounding the body's edge. It's on a purplish red leaf. The insect in life is only a couple millimeters long.

Close up of a whitefly pupa (Parabemisia myricae). It is a flat, shiny translucent green, wrinkly oval with evenly spaced flat rays of white wax surrounding the body's edge. It's on a green leaf. The insect in life is only a couple millimeters long.

Close up of a whitefly pupa (Parabemisia myricae). It is a flat, shiny translucent green, wrinkly oval with evenly spaced flat rays of white wax surrounding the body's edge. It's on a green leaf. The insect in life is only a couple millimeters long.

Close up of a whitefly pupa (Aleurochiton forbesii) from a maple bonsai. It is slightly raised off the leaf surface by wax like a small cake, and is brown and tan mottled with a roughened surface. It's on a greenish gray leaf. The insect in life is only a couple millimeters long.

Close up of a whitefly pupa (Aleurochiton forbesii) from a maple bonsai. It is slightly raised off the leaf surface by wax like a small cake, and is brown and tan mottled with a roughened surface. It's on a greenish gray leaf. The insect in life is only a couple millimeters long.

Close up of a whitefly pupa (Aleuroplatus). It is a flat, shiny black, wrinkly oval obscured by numerous wax plates coming out of the top, looking like white or translucent hard candy ribbons. It's on a green leaf. The insect in life is only a couple millimeters long.

Close up of a whitefly pupa (Aleuroplatus). It is a flat, shiny black, wrinkly oval obscured by numerous wax plates coming out of the top, looking like white or translucent hard candy ribbons. It's on a green leaf. The insect in life is only a couple millimeters long.

What's that? The world is insane, but you need your wonderfully-alien-yet-beautiful critters?

Say. No. More. 😎

Welcome to the microscopic world of #whitefly pupae. Under your nose & on your plants, these tiny bugs are suckin' juices & lookin' snazzy [adults, not so much]

#Hemiptera #Aleyrodidae

12.03.2025 22:44 — 👍 237    🔁 48    💬 5    📌 2
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Individual leaf microbiota tunes a genetic regulatory network to promote leaf growth Custódio et al. reveal a microbiota-driven mechanism that requires the repression of a plant defense genetic circuit. This mechanism modulates the growth-defense trade-off to prioritize leaf growth ov...

Individual leaf microbiota tunes a genetic regulatory network to promote leaf growth

@cp-cellhostmicrobe.bsky.social from Gabriel Castrillo

www.cell.com/cell-host-mi...

01.03.2025 12:57 — 👍 32    🔁 11    💬 0    📌 1
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Co jest największym skarbem naszej Pracowni? Nie zaskoczę - nie sprzęty czy zbiory danych (a trochę mózgów ponagrywaliśmy i poskanowaliśmy), ale ludzie, którzy mimo wszystkich przeciwności dalej chcą robić naukę i dociekać co z tą samotnością.. #SkarbyNaukowców #3procentnanaukę #pokolenieNCN

17.02.2025 14:46 — 👍 8    🔁 1    💬 0    📌 0
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A link between yogurt intake and reduce risk of colon cancer, from cohort of over 130,00 participants, with inverse relationship to Bifidobacterium in gut microbiome
www.tandfonline.com/doi/full/10.... open-access

12.02.2025 18:18 — 👍 444    🔁 94    💬 7    📌 12
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Genetic variability in the 3'UTR RNA1 of tomato torrado virus: implications for virus transmission by whitefly Trialeurodes vaporariorum from plant to plant Tomato torrado virus (ToTV) is a whitefly-transmitted pathogen causing tomato necrosis. ToTV’s genome consists of two positive single-stranded RNAs, w…

Genetic variability in the 3'UTR RNA1 of tomato torrado virus - implications for virus #transmission by whiteflies

The next paper from our lab
with Marta Budziszewska - the lead scientist
🦠🍅

#torradovirus #plantscience #virology #plantpathology

www.sciencedirect.com/science/arti...

07.02.2025 07:26 — 👍 3    🔁 1    💬 0    📌 0

In a satellite meeting at ISMPMI2025, I will talk about mentoring. I would like to know what mentors and mentees want to know. Let me know~

05.02.2025 00:50 — 👍 7    🔁 6    💬 1    📌 1
When the α-latrotoxin binds to the receptor of the presynaptic membrane of the signaling cell, it undergoes a transformation: part of the molecule forms a stalk that penetrates the cell membrane ("membrane insertion," right). As a special feature, this stalk forms a small pore in the membrane that acts as a calcium channel. MD simulations revealed that calcium ions (Ca2+ ions) enter the cell through a lateral selective gate directly above the pore. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-52635-5

When the α-latrotoxin binds to the receptor of the presynaptic membrane of the signaling cell, it undergoes a transformation: part of the molecule forms a stalk that penetrates the cell membrane ("membrane insertion," right). As a special feature, this stalk forms a small pore in the membrane that acts as a calcium channel. MD simulations revealed that calcium ions (Ca2+ ions) enter the cell through a lateral selective gate directly above the pore. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-52635-5

The poison of the black widow #spider acts like a #resistosome. 😲

#PlantScience meets #Arachnology

phys.org/news/2024-10...

08.10.2024 12:33 — 👍 20    🔁 5    💬 1    📌 0
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Welcome at Contrea - Contrea - Consultancy Training Research Welcome at Contrea Hi, my name is Marta. Welcome to my site. Almost 20 years working in academia, healthcare, education and industry sectors and working with colleagues and students from all over the ...

This is the second year since I started working as an independent researcher and lecturer. My full offer is available at contrea.eu

27.01.2025 10:14 — 👍 2    🔁 2    💬 0    📌 1
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RNA molecule rejuvenates ageing mice by restoring old cells Mice injected with a microRNA molecule lived longer and had fewer markers of ageing, but it’s not yet known if the treatment would work in people.

🧪Cool new science showing that delivery of an miRNA appears to affect aging #RNA #RNAsky

www.nature.com/articles/d41...

20.01.2025 21:00 — 👍 46    🔁 11    💬 2    📌 1
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A very interesting day and still a few hours to go 🙂
We have a new team member - Diksha Kumari - welcome to our lab! 👋🙂
Moreover,we started the search for a signal from microcosm, namely from inside of cells in our samples,in cooperation with IBCH.
We hope for interesting results!

17.01.2025 13:37 — 👍 1    🔁 0    💬 0    📌 0
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Coffee drinking timing and mortality in US adults AbstractBackground and Aims. To identify the patterns of coffee drinking timing in the US population and evaluate their associations with all-cause and cau

For coffee lovers:

'Conclusions
Drinking coffee in the morning may be more strongly associated with a lower risk of mortality than drinking coffee later in the day'

academic.oup.com/eurheartj/ad...

12.01.2025 07:46 — 👍 1    🔁 0    💬 0    📌 0
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Biological Reviews: Vol 100, No 1 Click on the title to browse this issue

Our publication on satellite RNAs associated with plant viruses
( onlinelibrary.wiley.com/doi/10.1111/... ) appeared in the first issue of 'Biological Reviews' in 2025, along with a number of very interesting papers.

onlinelibrary.wiley.com/toc/1469185x...

10.01.2025 10:45 — 👍 0    🔁 0    💬 0    📌 0

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