Maggi Skowron

Neues aus der Grundlagenforschung bei den Keimzelltumoren des Hodens und aktualisierte Tumorigenese - Die Urologie Type II testicular germ cell tumors (GCT) are the most common malignant disease in young men, with a steadily increasing incidence. They originate from germ cell neoplasia in situ and are classified i...

Für alle #Urologie / #Onkologie Interessierten - wir haben einen Beitrag in "Die Urologie" zu neuen Erkenntnissen aus der Grundlagenforschung und einer aktualisierten Betrachtung der Entstehung von #Keimzelltumoren verfasst...

@hhu.de
#CIOABCD

link.springer.com/article/10.1...

11.09.2025 11:42 — 👍 3    🔁 1    💬 0    📌 0

Had a great time at the annual meeting of the German Society of Pathology in @stadtleipzig.bsky.social! It was a pleasure to present our data from Düsseldorf together with @dannett1980.bsky.social and Yue Che. We also had a great evening exploring Gondwanaland 🌿

@hhu.de

14.06.2025 09:46 — 👍 1    🔁 0    💬 0    📌 0

A milestone reached, a journey continues 🍾 Thanks to everyone who made this possible!

10.04.2025 17:21 — 👍 1    🔁 0    💬 0    📌 0

Induction of SOX17 with stimulation of WNT, TGF‐beta, and FGF signaling drives embryonal carcinomas into the yolk‐sac tumor lineage resulting in increased cisplatin resistance Yolk-sac tumor formation has been suggested to be an escape mechanism during therapy in patients with relapsing germ cell tumors. The molecular mechanisms inducing yolk-sac tumor development from ste...

In our recent article, we demonstrate that the orchestrated activation of #SOX17 and #WNT, #TGF-beta and #FGF signaling drives embryonal carcinomas into the yolk-sac tumor lineage, which is accompanied by acquisition of cisplatin resistance…

onlinelibrary.wiley.com/doi/full/10....

03.03.2025 18:16 — 👍 2    🔁 1    💬 1    📌 0

Herzlichen Glückwunsch 🥂🎓💯

02.02.2025 00:42 — 👍 0    🔁 0    💬 0    📌 0