Vicki Metzis

I am absolutely delighted to share the invited speakers for our upcoming @bsdb.bsky.social "Molecules to Morphogenesis" meeting!

Registration and abstract submission is now open - join us!

bsdb.org/meetings/

March 23-26, 2026 - UK

Many thanks James - pleased to share this publication and to see it highlighted in the current issue @cp-devcell.bsky.social

Application deadline for up to 5 @mrc-lms.bsky.social postdoc positions in developmental epigenetics closes soon - don’t miss out! Positions across both experimental and computational projects. Come and join our fantastic team science community!

MRC Postdoctoral Research Scientists x 5 - MRC Laboratory of Medical Sciences Applications are now open for up to five postdoctoral positions in the area of developmental epigenetics.

Interested in developmental epigenetics? So are we! Apply now to join us for your postdoc!

Multiple positions across multiple groups @mrc-lms.bsky.social

Projects spanning germline demethylation, gene regulation, genome architecture in development & disease 👇👇

lms.mrc.ac.uk/work/vacanci...

My team @ebi.embl.org is open to hosting #ARISE2 fellows!

We‘re especially interested in projects that improve access to single-cell & spatial transcriptomics data (e.g. browsers, standards), or enhance AI-readiness.

Happy to chat if you are applying!

www.embl.org/training/ari...

Congratulations to my colleague Will Scott @mrc-lms.bsky.social on his latest work resolving the molecular changes in fat tissue that emerge following weight loss www.nature.com/articles/s41...

Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes - Nature Genetics Activation of an LTR retrotransposon inserted upstream of the Fgf8 gene produces viral-like particles in the mouse developing limb, triggering apoptosis and causing limb malformation. This phenotype c...

Finally out! 🥳 Our paper showing how a transposable element (TE) insertion can cause developmental phenotypes is now published @natgenet.nature.com 🧬🦠🐁
Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5

Very nice Juliane, great to see it out!

Science Technology Graduate Programme - MRC Laboratory of Medical Sciences Bioinformatics Facility - Dr George Young and Electron Microscopy Facility - Dr Ricardo Aramayo

Are you a recent UK graduate without an MSc, eager to launch your career in biomedical research?

Apply now for our two-year Science Technology Graduate Programme!

You'll gain hands-on experience in state-of-the-art research facilities, build technical expertise and earn a competitive salary.

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature Communications Redox signalling is emerging as an important regulator of metabolism and physiology, which is dysregulated in ageing and disease. Here, the authors show that redox regulation of a key redox sensitive ...

🎉Excited to share our latest paper, published in Nature Communications!🎉

"Enhancing autophagy by redox regulation extends lifespan in Drosophila"

#redox #metabolism #ageing #Drosophila

@natcomms.nature.com @mrc-lms.bsky.social

doi.org/10.1038/s414...

Range extender mediates long-distance enhancer activity - Nature The REX element is associated with long-range enhancer–promoter interactions.

Our paper describing the Range Extender element which is required and sufficient for long-range enhancer activation at the Shh locus is now available at @nature.com. Congrats to @gracebower.bsky.social who led the study. Below is a brief summary of the main findings www.nature.com/articles/s41... 1/

Thanks a lot Joaquina!

Many thanks Silvia!

Thanks a lot Juliane!

Thanks a lot Kristina!

Genetic “Dimmer Switch” Offers Precise Gene Expression Control The duration of expression of the gene Cdx2 is tightly regulated by a newly identified DNA sequence element called an “attenuator.”

Many thanks to @drsingleman.bsky.social for interviewing us about our latest work @imperialmed.bsky.social @mrc-lms.bsky.social - here’s her news story in GEN

www.genengnews.com/topics/genom...

Thanks very much!

I am happy and extremely proud to be able to contribute to this work with Irène Amblard and @vmetzis.bsky.social, where by changing one motif we completely rewired the function of a regulatory element!🔬🧬 Now out in Developmental Cell!

Many thanks Nitzan!

Many thanks Marta!

Thank you Marco!

Thanks a lot Teresa!

Many thanks Maxim!

Thank you Antoine!

Thanks a lot Rob!

Thank you Alexandre! Finally :)

Thank you Anestis!

Thank you Aydan!

So glad you enjoyed it ! And thanks for the fabulous Elmo!

Thank you Marta!