Jeremy Elman's Avatar

Jeremy Elman

@jaelman.bsky.social

Alzheimer's & aging researcher at UC San Diego

202 Followers  |  381 Following  |  30 Posts  |  Joined: 26.12.2023  |  2.2036

Latest posts by jaelman.bsky.social on Bluesky

This world series should have come with a health warning.

02.11.2025 04:04 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I have a very clear memory of being a kid and seeing these at the county fair. My friend and I started giggling and the vendor yells at us, "What, you ain't never seen a mustard udder ya *explitive* *slur*!?"

I had never seen one before or since, but I think of them often.

22.10.2025 16:16 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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HAPPENING NOW: A MASSIVE crowd of protesters flood the streets of San Diego for a โ€œNo Kings Dayโ€ rally showing their love for America and standing up against the corrupt fascist Trump administration. look how huge it is

18.10.2025 18:34 โ€” ๐Ÿ‘ 4946    ๐Ÿ” 1350    ๐Ÿ’ฌ 66    ๐Ÿ“Œ 96

The best thing about skate videos is that just about every time I watch one, there's a moment where I think to myself "that's the coolest trick I've ever seen". Definitely held on this one

11.10.2025 22:18 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Check out our data! Please reach out if you're interested, we're happy to provide more info and we may have useful datasets (e.g., with extra cleaning or composite variables) to address specific questions. Raw and derived MRI data also available upon request for ~1/2 the cohort.

26.09.2025 15:28 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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two men are sitting next to each other and one of them says i 'm such an idiot ! ALT: two men are sitting next to each other and one of them says i 'm such an idiot !

I need a little bit less praise from Claude and a little more self-flagellation

18.09.2025 03:03 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Age of menopause and dementia risk in 10,832 women from the Swedish Twin Registry INTRODUCTION An earlier age of menopause (AOM) is hypothesized to increase vulnerability to the neuropathological processes of dementia, which begin in midlife. METHODS We tested this hypothesis i.....

New paper out from the lab, demonstrating a robust non-linear relationship between age at menopause and dementia risk. Fantastic work by post-doc Dr. Ursula Saelzler. alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

08.08.2025 03:48 โ€” ๐Ÿ‘ 2    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

If belief is trust in the absence of evidence, you could argue no team believes in their catchers more than the Padres

01.08.2025 04:21 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
This figure shows a higher rate of mild cognitive impairment among people with moderate to severe chronic pain versus mild or no chronic pain.

This figure shows a higher rate of mild cognitive impairment among people with moderate to severe chronic pain versus mild or no chronic pain.

Excited to share my new study with the
VETSA team (vetsa.bsky.social) with jaelman.bsky.social and matthewpanizzon.bsky.social published in #JINS showing that moderate-to-severe chronic pain and opioid use are independently related to risk of mild cognitive impairment. tinyurl.com/y88k5z4j

22.07.2025 23:08 โ€” ๐Ÿ‘ 2    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Multisite chronic pain: association with cognitive decline and post-mortem Alzheimerโ€™s biomarkers Bell et al. report that multisite chronic pain in older adults is linked to faster cognitive decline and increased Alzheimerโ€™s disease pathology, particula

Excited to share my new K01 work to understand chronic pain as an AD risk factor - a collaboration of the VETSA team (vetsa.bsky.social) with jaelman.bsky.social and matthewpanizzon.bsky.social and Rush Medical University using the ROSMAP data. academic.oup.com/braincomms/a...

22.07.2025 23:11 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Testing the causal impact of plasma amyloid on total Tau using a genetically informative sample of adult male twins The amyloid cascade hypothesis predicts that amyloid-beta (Aฮฒ) aggregation drives tau tangle accumulation. We tested competing causal and non-causal hโ€ฆ

Study from Nathan Gillespie testing causal associations of plasma amyloid on total tau using #VETSA twin data.
www.sciencedirect.com/science/arti...

22.07.2025 23:05 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Associations of history of traumatic brain injury with markers of brain health among older men in the Vietnam Era Twin Study of Aging Traumatic brain injury (TBI) is associated with increased risk of dementia, but it is unclear how earlier life TBI is related to brain health in olderโ€ฆ

Study by Alex Posis finding that TBI is associated with altered microstructure of certain WM tracts that may persist at least 4 decades after the injury.

www.sciencedirect.com/science/arti...

22.07.2025 22:56 โ€” ๐Ÿ‘ 0    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Happy to share a new published study link.springer.com/article/10.1...
on subjective memory concern, negative affect, and cortical microstructure using @vetsa.bsky.social dataset and supported by a K01 grant from the NIA!

22.07.2025 22:49 โ€” ๐Ÿ‘ 4    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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โ€ผ๏ธNEW PREPRINTโ€ผ๏ธ

What if you could take a normal 3T T1w MRI and make it look like it was acquired from a 7T scanner?

That's exactly what we do using AI in our new preprint!

Link: arxiv.org/abs/2507.13782

#neuroskyence #neurosky #compneuro #AI #datascience #neurology #mrisky #neuroimaging

22.07.2025 03:34 โ€” ๐Ÿ‘ 46    ๐Ÿ” 18    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 3

Incredibly excited for this new work from our lab. We test the potential of AI-based neurodegenerative disease diagnostics using plasma proteomics data from n>17,000 people, led by the brilliant and indefatigable @anlijuncn.bsky.social Check it out!๐Ÿ‘‡

17.07.2025 05:51 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

It must be so hard for him in the tech world where, based on his griping, I assume he's usually the only white guy in the room.

12.07.2025 14:16 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Trump administration freezes $50 million in San Diego County public school funding A federal education grant funding freeze is affecting many school districts across San Diego County. Millions of dollars of public school funding are in limbo.

Tell me again how immigrants are to blame for lack of school funding
www.kpbs.org/news/educati...

11.07.2025 19:41 โ€” ๐Ÿ‘ 6    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
GitHub - jelman/TreeForge: A modern web-based application for creating, editing, and visualizing folder structures with drag-and-drop functionality A modern web-based application for creating, editing, and visualizing folder structures with drag-and-drop functionality - jelman/TreeForge

Big caveat: Although it does what I need it to, this is essentially 100% AI created so YMMV. Github repo below if you'd like to modify or build a local app. Hope it's useful!

github.com/jelman/TreeF...

09.07.2025 21:12 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

With TreeForge you can:
1. Drag and drop folders/files in a visual editor
2. Toggle between markdown (for easier editing) and ASCII (for better visualization) in a text editor
3. Edits sync across windows
3. Import/export JSON and ASCII files to send to others and for data documentation.

09.07.2025 21:12 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Screenshot of the TreeForge web app with visual editor on the left and text editor on the right

Screenshot of the TreeForge web app with visual editor on the left and text editor on the right

Trying to create directory tree for a new project or storage location? I did, but couldn't find an app that did exactly what I wanted, so I had GitHub Copilot + Claude create an app for me.

Link to the web app: jelman.github.io/TreeForge/

09.07.2025 21:12 โ€” ๐Ÿ‘ 0    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

The onslaught of 2025 can be so isolating. Today was a really great reminder that we're a community, and a large one at that.

14.06.2025 23:26 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I'm so sorry Heidi, that is truly awful news. The work you and your colleagues do is necessary and important, and we are all worse off for this. If there is anything I can do, please reach out.

02.06.2025 20:04 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Blood-brain barrier permeability varies by brain region and APOE4 status and correlates with brain microstructure among high-AD risk groups Although strong evidence exists for bloodโ€“brain barrier (BBB) disruption in Alzheimerโ€™s disease (AD), substantial uncertainty remains regarding its roโ€ฆ

New work from our postdoc Seraphina Solders shows patterns of blood-brain barrier leakage in cognitively normal APOE4 carriers. BBB breakdown correlated with microstructural brain injury only in groups with high Alzheimer's disease risk (APOE4+, amyloid+, women) www.sciencedirect.com/science/arti...

02.06.2025 01:27 โ€” ๐Ÿ‘ 7    ๐Ÿ” 5    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Everything about this was intended to provoke a response. They wouldn't have brought that show of force to that restaurant on that corner on a Friday evening if they didn't want to attract attention.

01.06.2025 02:39 โ€” ๐Ÿ‘ 31    ๐Ÿ” 2    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1

This is a popular neighborhood restaurant on a corner with a lot of foot traffic. Rolling in like this on a Friday evening could only have been meant to send a message. It was guaranteed to be packed with folks from the neighborhood, including kids. No wonder they cover their faces.

31.05.2025 16:48 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Federal cuts to National Institutes of Health could threaten medical progress Former National Institutes of Health Director Dr. Francis Collins, who abruptly left his NIH research lab in February, fears aggressive downsizing could impact Americansโ€™ health.

Thank you @60minutes.bsky.social for giving the NIH freezes, termination, and proposed budget cuts the attention they deserve. ALL Americans, regardless of party, will feel this impact to their health far beyond one administration. www.cbsnews.com/video/nih-cu...

28.04.2025 12:15 โ€” ๐Ÿ‘ 14    ๐Ÿ” 9    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Although I suppose he would also consider this to be the desired outcome...

13.04.2025 02:07 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Is he unaware that, at least in schools of medicine, there has been a huge shift towards soft money positions? This is presumably the type of move he would support, even though we are seeing right now how this type of system leaves people vulnerable to the whims of the Executive branch.

13.04.2025 02:04 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

This Passover Iโ€™m thinking hard about the holidayโ€™s history of resistance to tyrannical leaders, and the imperative for Jewish people to stand with all oppressed peoples of the world.

13.04.2025 00:53 โ€” ๐Ÿ‘ 4343    ๐Ÿ” 608    ๐Ÿ’ฌ 58    ๐Ÿ“Œ 31
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Revealed: NIH research grants still frozen despite lawsuits challenging Trump order The Trump administration is exploiting a loophole to keep a funding freeze in place, leaving researchers in limbo.

NEW: The Trump administration is exploiting a loophole to keep funding frozen at the NIH - a move that some legal scholars say is illegal.

Federal Register notices are blocked, so no grant-review sessions can be scheduled.

All the gritty details here, and a short ๐Ÿงต:
www.nature.com/articles/d41...

20.02.2025 20:27 โ€” ๐Ÿ‘ 161    ๐Ÿ” 121    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 25

@jaelman is following 20 prominent accounts