Find in @narjournal.bsky.social our latest kPPA-CART, a new effective framework for your multi-omics analysis.
πhttps://academic.oup.com/nar/article/doi/10.1093/nar/gkaf844/8257763?utm_source=authortollfreelink&utm_campaign=nar&utm_medium=email&guestAccessKey=44031ac6-ca6c-47a7-bea5-f5a13e8e45e3
23.09.2025 18:48 β π 0 π 1 π¬ 0 π 0
Proof?
β’ Improved breast cancer subtyping vs PAM50
β’ Links to survival + tumor mutational burden
β’ Free R package + web app for the community
π www.karakachlab.org/software/int...
21.09.2025 17:23 β π 3 π 1 π¬ 0 π 0
The solution: kPPA-CART
It digs into those low-signal regions, integrates transcriptomics, proteomics & methylation data, and finds real biological meaning others miss.
21.09.2025 17:23 β π 0 π 1 π¬ 0 π 0
Whatβs the problem? π€
Most computational tools in bioinformatics only detect strong, obvious signals. Subtle, low-intensity features (the ones that really matter for biology) get lost in the noise.
21.09.2025 17:22 β π 1 π 1 π¬ 0 π 0
Like Dj Khalid, another one from the KarakachLab!
We just dropped kPPA-CART in @narjournal.bsky.social, a new machine learning method that finds hidden signals in messy multi-omics data. From kidney aging 𧬠to breast cancer ποΈ, it uncovers patterns others miss.
doi.org/10.1093/nar/...
21.09.2025 17:19 β π 2 π 1 π¬ 0 π 1
Scientist interested in RNA and gene regulation. My passions are paraspeckles, RNA therapeutics for cancer and everything hiking/nature/community.
Epigenetic Inheritance, Neuroscience & anything biology-related
https://www.odedrechavilab.com/
https://www.qedscience.com
Organizer of βThe Woodstock of Biologyβ
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Huberman Lab Podcast: https://youtu.be/CDUetQMKM6g
noncoding RNA, chromatin and cancer researcher
Director of DNA and RNA Medicine Division @CIMA_unav
Pamplona, Spain
ERC awardee. Music lover (bad violin player) and mother
Assistant Professor @IRCM, @McGill Center for RNA Sciences, @UdeM.
RNA Biology, lncRNA, RNA Therapy, Genome Regulation sauvageaulab.org
Molecular biologist interested in non-coding RNAs, nuclear organization, and gene regulation. Professor at Caltech
Associate Professor, Weizmann Institute of Science. RNA biologist, interested in what (long) RNA molecules do and how. Father of 4.
RNA and cancer biologist (opinions, usually strong, are mine)
https://gbiomed.kuleuven.be/english/research/50488876/54502087/research
https://gbiomed.kuleuven.be/english/research/50488876/54502087/Trace
Assistant Professor; Scientist; Stoic; Humanist;
Neither an unreasonable conservative idiot nor a liberal freak.
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