Alex Bisson

HALOPHILES YESSSSSSSS

Can't miss this amazing study on the ribosome structure of the Haloferax archaeon 👏🏼👏🏼👏🏼!! Congrats to my good friend @diorgeps.bsky.social and all the other ppl involved!!

Diorge's thread is great, but I am the most impressed how, thanks to many labs (including Davis-MIT), cryo pipelines became streamlined that one can perturb cells and screen for complex sub-populations.

So much cell (structural) biology will come out from Diorge's future lab!

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Another paper on a topic we never worked on before: a new ribosomal hibernation!

Under the leadership of the super-postdoc Diorge, Davis Lab (ribo-cryoEM master), and @vikramalva.bsky.social (protein-evo whisperer), we identified AHA (not the song, but archaeal hibernation AMPKγ factor).

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Very cool work led by @diorgeps.bsky.social from the labs of @archaeon-alex.bsky.social & Joey Davis (MIT)!

They solved the Haloferax volcanii ribosome and characterize AHA, a conserved archaeal hibernation factor.

With several recent related preprints, it’s an exciting moment for the field!

Excited to share this new Preprint from our lab led by PhD Candidate Carl Stone (defending Tuesday).

Here we present a framework for longitudinal rbTn-Seq and apply it to the Microbial extended growth curve to resolve the fitness seascape through growth, death, and long-term stationary phase!

Lowering the temperature allows transitions from the ‘sol-sol’ to the ‘sol-gel’ region, which manifest with a jump in the total volume fraction of the protein-rich phase.

The interplay between biomolecular assembly and phase separation.

🔗 buff.ly/lvTQhIM

Over the moon for being on the 4th. Everyone is beyond above the curve there.

I can't blame you. Yes, I'll have to go to CH and get a bit of your awesomeness.

Congrats on the new (yet another) breathtaking paper. You're a machine. ❤️

Thank you, Jen. I've been very lucky in my life, and this is indeed huge for me and my lab.

Thanks, Ariane! Maybe we should connect and see if there is anything we can collaborate. We are always happy to image new bugs and have tons of questions perfect for cell-struct Approaches!

Thanks, Duygu! Now that we're close enough, maybe we can organize a joint lab retreat!

Deep Learning for Microscopy Image Analysis Topics The following will be covered extensively during lectures, exercises, and project work: Image denoising and restoration (fully supervised and self-supervised) Image translation (e.g.,

🚨 Alarm!!! 🚨
AI/ML course for microscopy image analysis!!! 🧐
In 2026 at Janelia (@hhmijanelia.bsky.social), no tuition, housing and meals provided! Isn’t that borderline unbelievable?!?

20 students, ~14 TAs and lecturers
🗓️ June 4-18 2026

✍️ Jan 15 2026 ✍️

🔁 pls!!

www.janelia.org/you-janelia/...

Thanks, Michael! I hope you can come visit and give a talk here. Both Micro and Evo-Sys folks would love your science

Thanks, Omaya! I hope to convince you to come visit us.

Thanks, Geo!

Another #notTHECover unfortunately.

But this gorgeous, Tron-like vibe, drawn by the amazing @munafomarzia.bsky.social for our recent #ExM work with @gautamdey.bsky.social & @centriolelab.bsky.social will still be printed out in the lab.

Read here: www.cell.com/cell/fulltex...

Obrigado, Júlia! Eu estava pensando em você no outro dia. Espero que esteja bem! Mande notícias!

Thanks, Mark! Midwest is the best. I am happy we are a but closer now. I hope we can bump into each other more frequently now!

Thanks, Mark!

I love Bloomington! Feels amazing to be here.

Obrigado, Dirk!

funny you say it, my future lab space is next to the fly kitchen. I can't escape them.

but model organisms is too démodé. Non-models are the next thing ;)

midwest rules!

Tks Thibaut. Looking forward to having you visiting us in Bloomington!

Thanks, Alejandro! Looking forward to see you in 2026 in salt lake!

I would not be here if it wasn't for Brandeis University. They believed in me and that I would make a research program out of a couple of crazy ideas. I leave friends and active collaborators there. I will literally carry Brandeis motto “Truth, Even Unto Its Innermost Parts” with me forever.

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I also want to thank the Bisson Lab members (past and present) for the past 6 years of personal, professional, and intellectual growth. They taught me new fields and how to become a better manager (work in progress). They shared their passion for science and allowed me to share mine.

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We’ll continue to focus on archaeal cell mechanobiology and tool-building to study microbial life.

I am deeply grateful to everyone at IU-Bio. It is a privilege to join a department with a foundational legacy in microbiology, shaped by figures such as Salvador Luria and Giuseppe Bertani

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I am beyond excited to announce that the Bisson Lab has a new home!!! Starting January 2026, I will join the Biology Department at Indiana University Bloomington as Associate Professor with tenure.

I am actively recruiting scientists across all levels. More in our website: bissonlab.com/join

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