Mac Shine

𝗔 𝗡𝗘𝗨𝗥𝗢𝗘𝗖𝗢𝗟𝗢𝗚𝗜𝗖𝗔𝗟 𝗣𝗘𝗥𝗦𝗣𝗘𝗖𝗧𝗜𝗩𝗘 𝗢𝗡 𝗧𝗛𝗘 𝗣𝗥𝗘𝗙𝗥𝗢𝗡𝗧𝗔𝗟 𝗖𝗢𝗥𝗧𝗘𝗫
By Mars and Passingham
"Understanding anthropoid foraging challenges may thus contribute to our understanding of human cognition"
Going to the top of the reading list!
doi.org/10.1016/j.ne...
#neuroskyence

Would love to revisit this idea if ppl are still keen. Was a fun project to work on.

Thanks Deb!

update - i found a copy. thanks all for boosting!

random neuroimaging question: does anyone in bluesky-land have access to the loadings for neurosynth topics in schaefer 400 (yeo7) space? #neuroskyence @misicbata.bsky.social @richardfbetzel.bsky.social @borismontreal.bsky.social @sofievalk.bsky.social

Granularity of thalamic head direction cells Head direction signaling is fundamental for spatial orientation and navigation. The anterodorsal nucleus of the thalamus (ADn) contains a high density of head direction (HD) cells that process sensori...

*New preprint from the lab* – “Granularity of thalamic head direction cells”
doi.org/10.1101/2025...
🧠📈 🧪
1/11

There's lots of opportunities in the brain for closures of these kinds, though I fear that this ultimately raises another set of even-more challenging questions: namely, how do our brains decipher between different circuit closures if they differ in their constraints? Fun to think about...

The short answer is yes, but we were quite limited in writing that paper to keep the text short and the references mostly to the last few years. I'm certainly not an expert on circular causality/constraint closure, but I do very much like the implications of the ideas

What changes and what stays the same as you scale from single neurons up to local populations of neurons up to whole brains?

Michael and Mac @macshine.bsky.social on the systems approach to study brains across scales.

braininspired.co/podcast/220/

Compositional neural dynamics during reaching The complex mechanics of the arm make the neural control of reaching inherently posture dependent. Because previous reaching studies confound reach direction with final posture, it remains unknown how...

Excited to share my latest work with @jonathanamichaels.bsky.social @diedrichsenjorn.bsky.social & @andpru.bsky.social!
We asked: How does the motor cortex account for arm posture when generating movement?
Paper 👉 www.biorxiv.org/content/10.1...
1/10

Adaptive learning is coordinated across behaviour, time and neurobiology (from synapses and dendrites, to astrocytes and the systems level).

If you’ve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this: www.cell.com/trends/cogni...

great episode! covered lots of cool territory -- great to see the concept of affordances coming back into the spotlight

Theoretical neuroscience has room to grow — a Comment article by Ann Kennedy

@antihebbiann.bsky.social

#neuroscience #neuroskyence

www.nature.com/articles/s41...

Massive congratulations Annie! Thoroughly well-deserved!!

Should have guessed that you would know the precise quote ;)

Neurophysiologist and philosopher Walter Freeman dies at 89 - Berkeley News Pioneering neuroscientist focused on how the brain generates our perception of the world

Haha yep. The son of the lobotomist... news.berkeley.edu/2016/04/27/n...

a cartoon of a man with braces on his teeth says i think we have a winner ALT: a cartoon of a man with braces on his teeth says i think we have a winner

thanks mate! much appreciated

@dryohanjohn.bsky.social @drbreaky.bsky.social @christopherjwhyte.bsky.social

I need some help from the #neuroskyence Bluesky-verse. Anyone know the source of this ~quote from Walter J. Freeman Jr.: "the secrets of the brain are hidden by two of God’s own firewalls: neurobiology and non-linear dynamics". I read it yrs ago but can't seem to find my way back to the source.

Serotonin drives choice-independent reconfiguration of distributed neural activity Serotonin (5-HT) is a central neuromodulator which is implicated in, amongst other functions, cognitive flexibility. 5-HT is released from the dorsal raphe nucleus (DRN) throughout nearly the entire f...

🚨Pre-print alert🚨

We stimulated serotonin with optogenetics while doing large-scale Neuropixel recordings across the mouse brain. We found strong widespread modulation of neural activity, but no effect on the choices of the mouse 🐭

How is this possible? Strap in! (1/9) 👇🧵

doi.org/10.1101/2025...

🚨 California and Hawaii under tsunami watch after 8.7M quake in Eastern Russia.

Tsunami Warning

Tsunami Warning – 7/30, 9:40am
The Tsunami Advisory has been upgraded to a Tsunami Warning. Waves of up to 3m are expected. Those near coastal areas, rivers, or lakes should evacuate to higher ground immediately. #tsunami

Evolutionary trade-off between vocal tract and testes dimensions in howler monkeys - PubMed Males often face a trade-off between investments in precopulatory and postcopulatory traits [1], particularly when male-male contest competition determines access to mates [2]. To date, studies of pre...

The point is, the monkeys making the loudest noise have the smallest balls.
pubmed.ncbi.nlm.nih.gov/26592343/

Dem leadership should appoint an official Alt Press Secretary to give briefings after every one that Karoline Leavett does and just break them down lie by lie

maybe THAT’S the job we give Colbert 😂

An exciting collaboration is underway. @thetransmitter.bsky.social is partnering with @neuromatch.bsky.social to serve the computational neuroscience community and help connect neuroscientists across all career stages.
www.thetransmitter.org/neuromatch-p...

#neuroskyence

“the kindest person in the room is often the smartest.” JB Pritzker is a mensch.

Prefrontal axons going to lots of places!
doi.org/10.1016/j.ce...
#neuroskyence

Cooperative thalamocortical circuit mechanism for sensory prediction errors - Nature Experiments in mice show that a cortico-thalamic circuit generates prediction-error signals in primary visual cortex that amplify visual input that deviates from animals’ expectations.

Pairs well with www.nature.com/articles/s41...

“Our results indicate that individual V1 neurons do not signal how the actual visual input deviates from the animal’s predictions, as postulated within the predictive coding framework”

Thrilling to see a major theory get tested!

GLP-1 and the Neurobiology of Eating Control: Recent Advances Abstract. Obesity is now considered a chronic relapsing progressive disease, associated with increased all-cause mortality that scales with body weight, af

Really proud to start the year by sharing our new review in @endosocjournals.bsky.social on the roles of GLP-1 in eating and obesity treatment, led by superstar postdoc @laurenjonesucl.bsky.social!

academic.oup.com/endo/article...

🧪🧠📈 #neuroscience #neuroskyence #GLP-1 #obesity #wegovy #ozempic